scholarly journals MP26-04 ROLE OF ADJUVANT CISPLATIN-BASED CHEMOTHERAPY FOLLOWING RADICAL CYSTECTOMY IN MUSCLE-INVASIVE AND LOCALLY ADVANCED BLADDER CANCER: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED TRIALS

2019 ◽  
Vol 201 (Supplement 4) ◽  
Author(s):  
Do Kyung Kim* ◽  
Joo Yong Lee ◽  
Jae Hung Jung ◽  
Yoon Soo Hah ◽  
Kyo Chul Koo ◽  
...  
Author(s):  
Vikram M. Narayan

This study summarizes a landmark study on the role of neoadjuvant chemotherapy with methotrexate, vinblastine, doxorubicin, and cisplatin (M-VAC) in patients with muscle-invasive bladder cancer. This randomized study of M-VAC plus cystectomy versus cystectomy alone suggested improved overall survival in patients receiving neoadjuvant therapy. Severe granulocytopenia was a common adverse effect in the chemotherapy group, but no deaths were attributed to chemotherapy.


2018 ◽  
Vol 4 (4) ◽  
pp. 558-567 ◽  
Author(s):  
Angelo Naselli ◽  
Rodolfo Hurle ◽  
Stefano Paparella ◽  
Nicolò Maria Buffi ◽  
Giovanni Lughezzani ◽  
...  

Author(s):  
Mieszko Kozikowski ◽  
Rodrigo Suarez-Ibarrola ◽  
Rafał Osiecki ◽  
Konrad Bilski ◽  
Christian Gratzke ◽  
...  

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