Significance of Extent of Lobular Neoplasia on Breast Core Biopsy

2005 ◽  
Vol 7 (4) ◽  
pp. 150-156 ◽  
Author(s):  
Eva C Gombos ◽  
Juan Godinez ◽  
Robert J Poppiti
Keyword(s):  
Core Biopsy ◽  
Lobular Neoplasia

scholarly journals Classic lobular neoplasia on core biopsy: a clinical and radio-pathologic correlation study with follow-up excision biopsy

2013 ◽  
Vol 26 (6) ◽  
pp. 762-771 ◽  
Author(s):  
Shweta Chaudhary ◽  
Loretta Lawrence ◽  
Geraldine McGinty ◽  
Karen Kostroff ◽  
Tawfiqul Bhuiya
Keyword(s):  
Core Biopsy ◽  
Correlation Study ◽  
Lobular Neoplasia ◽  
Excision Biopsy ◽  
Pathologic Correlation

Should the Extent of Lobular Neoplasia on Core Biopsy Influence the Decision for Excision?

2007 ◽  
Vol 13 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Lisa E. Esserman ◽  
Ladan Lamea ◽  
Silvio Tanev ◽  
Robert Poppiti
Keyword(s):  
Core Biopsy ◽  
Lobular Neoplasia

Invasive Mammary Carcinoma After Immediate and Short-Term Follow-up for Lobular Neoplasia on Core Biopsy

2003 ◽  
Vol 27 (3) ◽  
pp. 325-333 ◽  
Author(s):  
Giovanna Maria Crisi ◽  
Srinivas Mandavilli ◽  
Edward Cronin ◽  
Andrew Ricci,
Keyword(s):  
Mammary Carcinoma ◽  
Core Biopsy ◽  
Lobular Neoplasia ◽  
Short Term ◽  
Invasive Mammary Carcinoma

Lobular neoplasia: does 11 Gauge core biopsy allow to avoid surgical excision? A study of 58 consecutive cases

2006 ◽  
Vol 4 (2) ◽  
pp. 82-83
Author(s):  
M.P. Chauvet ◽  
Ceugnart ◽  
M.C. Baranzelli ◽  
S. Giard ◽  
R. Uzan ◽  
...  
Keyword(s):  
Core Biopsy ◽  
Surgical Excision ◽  
Lobular Neoplasia

Lobular neoplasia on core biopsy: Is excision always indicated?

2011 ◽  
Vol 29 (27_suppl) ◽  
pp. 75-75
Author(s):  
C. A. Makarewich ◽  
K. M. Rosenkranz
Keyword(s):  
Core Biopsy ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Incidental Finding ◽  
Lobular Carcinoma ◽  
Excisional Biopsy ◽  
Invasive Disease ◽  
Lobular Neoplasia ◽  
Occult Malignancy

75 Background: Lobular neoplasia (LN) is a continuum of rare, noninvasive lesions of the breast including lobular carcinoma in situ and atypical lobular hyperplasia. Current management is controversial and often includes excisional biopsy in women diagnosed with LN on percutaneous core biopsy (PCB) to exclude an occult malignancy. This strategy is based on retrospective data in women undergoing selective excisions. We performed routine excision of all lesions diagnosed as LN in our institution in order to ascertain a more accurate assessment of pathologic upgrade. Methods: Retrospective review of all prospectively collected cases of LN treated in a single institution from 2007-2010. Excisional biopsies were performed in all cases of LN excepting one (patient declined). Histologic findings of excisional biopsies were reviewed to assess the rate of pathologic upgrade. Results: Of the 2,289 PCBs performed during the study period, LN was found in 23 cases (1.0%). Twenty two (0.96%) cases proceeded to excisional biopsy. On final pathology, malignancy was found in 4 patients (18%). Two of 22 (9%) women were upgraded to ductal carcinoma in situ (DCIS) (both intermediate grade with foci of <1mm and 4mm) and 2/22 (9%) women were diagnosed with invasive lobular carcinoma. Conclusions: While 18% of women in our series had upgraded pathology at the time of excisional biopsy, we support selective rather than routine excisional biopsy. One of the invasive diagnoses was an incidental finding unrelated to the microcalcifications for which biopsy was initially performed. In the second case of invasive disease, the upgraded lesion was a mass identified on MRI performed for surgical planning in a woman already diagnosed with breast cancer. In both cases of DCIS, the area of malignancy was small (<1mm and 4mm) and of uncertain clinical significance. Based on these findings, we do not recommend routine excision of all LN identified on PCB. Cases in which the lesion is associated with a radiographic mass and/or is identified in a breast with a synchronous malignancy do warrant excisional biopsy. Patients without these high risk features can be counseled on the risks of malignancy and given the option of observation with close follow up.

Lobular neoplasia on core biopsy and risk factors to predict upstaging at surgical excision.

2009 ◽  
Author(s):  
M Alvarado ◽  
A Throckmorton ◽  
C Ewing ◽  
S Hwang ◽  
L Esserman ◽  
...  
Keyword(s):  
Risk Factors ◽  
Core Biopsy ◽  
Surgical Excision ◽  
Lobular Neoplasia
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