Intraductal carcinoma of prostate (IDC-P) and high-grade prostatic intraepithelial neoplasia (HGPIN) in prostate biopsy: why we should distinguish one from the other

Pathology ◽  
2013 ◽  
Vol 45 ◽  
pp. S70-S71
Author(s):  
Sureshni I. Jayasinghe ◽  
David Clouston
Keyword(s):  
Prostate Biopsy ◽  
Intraepithelial Neoplasia ◽  
Prostatic Intraepithelial Neoplasia ◽  
The Other ◽  
Intraductal Carcinoma ◽  
High Grade

scholarly journals Significance of Atypical Small Acinar Proliferation and High-Grade Prostatic Intraepithelial Neoplasia in Prostate Biopsy

2011 ◽  
Vol 52 (11) ◽  
pp. 736 ◽  
Author(s):  
Orhan Koca ◽  
Selahattin Çalışkan ◽  
Metin İshak Öztürk ◽  
Mustafa Güneş ◽  
M. Ihsan Karaman
Keyword(s):  
Prostate Biopsy ◽  
Intraepithelial Neoplasia ◽  
Prostatic Intraepithelial Neoplasia ◽  
High Grade ◽  
Atypical Small Acinar Proliferation

Managing high-grade prostatic intraepithelial neoplasia (HGPIN) and atypical glands on prostate biopsy

2017 ◽  
Vol 15 (1) ◽  
pp. 55-66 ◽  
Author(s):  
Jeffrey J. Tosoian ◽  
Ridwan Alam ◽  
Mark W. Ball ◽  
H. Ballentine Carter ◽  
Jonathan I. Epstein
Keyword(s):  
Prostate Biopsy ◽  
Intraepithelial Neoplasia ◽  
Prostatic Intraepithelial Neoplasia ◽  
High Grade

Intraductal Carcinoma of the Prostate Gland With Transmucosal Spread to the Seminal Vesicle: A Lesion Distinct From High-Grade Prostatic Intraepithelial Neoplasia

2007 ◽  
Vol 131 (7) ◽  
pp. 1122-1125 ◽  
Author(s):  
Ronald J. Cohen ◽  
Beverly A. Shannon ◽  
Sydney L. Weinstein
Keyword(s):  
Seminal Vesicle ◽  
Invasive Carcinoma ◽  
Prostate Gland ◽  
Ejaculatory Duct ◽  
Intraepithelial Neoplasia ◽  
Prostatic Intraepithelial Neoplasia ◽  
Intraductal Carcinoma ◽  
High Grade ◽  
Carcinoma Of The Prostate ◽  
High Stage

Abstract Intraductal carcinoma of the prostate (IDC-P) gland represents an intraluminal neoplastic proliferation that is distinct from high-grade prostatic intraepithelial neoplasia (HG-PIN) and almost always coexists with large-volume, high-stage, and high-grade invasive carcinoma. We document an unusual presentation of apparently “early” IDC-P without an aggressive invasive element that, despite being confined to the acinar-ductal system, has gained access to the ejaculatory duct and seminal vesicle by transmucosal spread. This finding confirms that IDC-P, in contrast to HG-PIN, is inherently aggressive and has the ability to spread beyond the prostate gland. In this case, the absence of an aggressive invasive element suggests that IDC-P has most likely evolved within the lumens directly from HG-PIN.

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