Establishing Clinical Cut-points on the Pediatric PROMIS-pain Interference Scale in Youth with Abdominal Pain

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kaitlyn L. Gamwell ◽  
Constance A. Mara ◽  
Kevin A. Hommel ◽  
Susmita Kashikar-Zuck ◽  
Natoshia R. Cunningham
2021 ◽  
pp. 000486742110446
Author(s):  
Melissa Stieler ◽  
Peter Pockney ◽  
Cassidy Campbell ◽  
Vaisnavi Thirugnanasundralingam ◽  
Lachlan Gan ◽  
...  

Background: Somatic disorders and somatic symptoms are common in primary care populations; however, little is known about the prevalence in surgical populations. Identification of inpatients with high somatic symptom burden and psychological co-morbidity could improve access to effective psychological therapies. Methods: Cross-sectional analysis ( n = 465) from a prospective longitudinal cohort study of consecutive adult admissions with non-traumatic abdominal pain, at a tertiary hospital in New South Wales, Australia. We estimated somatic symptom prevalence with the Patient Health Questionnaire-15 at three cut-points: moderate (⩾10), severe (⩾15) and ‘bothered a lot’ on ⩾3 symptoms; and psychological co-morbidity with the Patient Health Questionnaire-9 and Generalized Anxiety Disorder-7 at standard (⩾10) cut-points. We also examined gender differences for somatic symptoms and psychological co-morbidity. Results: Prevalence was moderate (52%), female predominance (odds ratio = 1.71; 95% confidence interval = [1.18, 2.48]), severe (20%), no gender difference (1.32; [0.83, 2.10]) and ‘bothered a lot’ on ⩾3 symptoms (53%), female predominance (2.07; [1.42, 3.03]). Co-morbidity of depressive, anxiety and somatic symptoms ranged from 8.2% to 15.9% with no gender differences. Conclusion: Somatic symptoms were common and psychological triple co-morbidity occurred in one-sixth of a clinical population admitted for abdominal pain. Co-ordinated surgical and psychological clinical intervention and changes in clinical service organisation may be warranted to provide optimal care.


2021 ◽  
Vol 42 (Supplement_1) ◽  
pp. S48-S49
Author(s):  
Gretchen J Carrougher ◽  
Alyssa M Bamer ◽  
Claudia Baker ◽  
Stephanie A Mason ◽  
Barclay T Stewart ◽  
...  

Abstract Introduction Pain is a common and often debilitating sequelae of a significant burn injury. Clinicians and researchers need clinically valid, reliable pain measures to guide treatment decisions and to provide evidence for study protocol development. Pain rating scores that represent mild, moderate, and severe pain in the burn survivor population have not been established. The aim of this study was to determine the numerical pain intensity rating scores that best represent mild, moderate, and severe pain in adult burn survivors. Methods Average pain intensity visual analog scale (VAS; 0–10) and customized PROMIS pain interference short form was administered to adult burn survivors (age ≥18) treated at a regional burn center at hospital discharge and at 6, 12, and 24-months postburn. To identify the optimal VAS scores for mild, moderate, and severe pain we computed F values and Bayesian Information Criterion (BIC) statistics associated with multiple ANOVA comparisons for mean pain interference scores by various VAS pain intensity cut points. Six possible cut points (CP) were compared: CP 3,6; CP 3,7; CP 4,6; CP 4,7; CP 2,5; and CP 3,5. For example, CP 3,6 refers to pain categorized as mild (0–3), moderate (4–6), and severe (7–10). Optimal cutoffs were those with the highest ANOVA F statistics. Models with similar F statistics were compared using changes in BIC. Results 178 participants (85% white, 65% male, mean age of 46 years) with pain intensity and interference scores at one or more timepoints comprised the study sample. The optimal classification for mild, moderate, and severe pain at baseline and 12-months was CP 2,5. Although CP 3,6 had the highest F value at 6-months, there was not strong evidence to support CP 3,6 over CP 2,5 (BIC difference: 2.9); similarly, CP 3,7 had the highest value at 24-months, but the BIC difference over CP 2,5 was minimal (2.2). Conclusions We recommend that visual analog pain intensity scores for adult burn survivors be categorized as mild (0–2), moderate (3–5), and severe (6–10). These findings advance our understanding regarding the meaning of pain intensity ratings following a burn injury and provide an objective definition for clinical management, quality improvement, and pain research.


VASA ◽  
2011 ◽  
Vol 40 (6) ◽  
pp. 495-498 ◽  
Author(s):  
Rajkovic ◽  
Zelic ◽  
Papes ◽  
Cizmek ◽  
Arslani

We present a case of combined celiac axis and superior mesenteric artery embolism in a 70-year-old patient that was examined in emergency department for atrial fibrillation and diffuse abdominal pain. Standard abdominal x-ray showed air in the portal vein. CT scan with contrast showed air in the lumen of the stomach and small intestine, bowel distension with wall thickening, and a free gallstone in the abdominal cavity. Massive embolism of both celiac axis and superior mesenteric artery was seen after contrast administration. On laparotomy, complete necrosis of the liver, spleen, stomach and small intestine was found. Gallbladder was gangrenous and perforated, and the gallstone had migrated into the abdominal cavity. We found free air that crackled on palpation of the veins of the gastric surface. The patient’s condition was incurable and she died of multiple organ failure a few hours after surgery. Acute visceral thromboembolism should always be excluded first if a combination of atrial fibrillation and abdominal pain exists. Determining the serum levels of d-dimers and lactate, combined with CT scan with contrast administration can, in most cases, confirm the diagnosis and lead to faster surgical intervention. It is crucial to act early on clinical suspicion and not to wait for the development of hard evidence.


Swiss Surgery ◽  
2000 ◽  
Vol 6 (1) ◽  
pp. 32-35 ◽  
Author(s):  
Kilgus ◽  
Largiadèr ◽  
Klotz

Einleitung: Bei der Differentialdiagnose von intraabdominalen Tumoren ist an die mesenterialen Zysten zu denken. Wir möchten mittels Fallbeispiel an diesen seltenen Befund erinnern. Fallbeispiel: Es handelt sich um eine 35-jährige Patientin mit zweiwöchiger Anamnese von progredienten Abdominalschmerzen. Die Abklärung mittels Sonographie und Computertomographie ergab einen 14 x 12 x 3cm grossen zystischen abdominalen Tumor ohne Beziehung zu Uterus, Adnexen oder Oberbauchorganen, worauf die Patientin laparotomiert und die Zyste reseziert wurde. Diskussion: Mesenteriale Zysten sind selten. Die Pathogenese ist unterschiedlich und die klinische wie auch die radiologische Diagnostik schwierig. Die Symptomatik reicht vom akuten Abdomen über unspezifische Abdominalbeschwerden bis hin zum asymptomatischen Zufallsbefund. Mesenteriale Zysten können entlang des gesamten Gastrointestinaltraktes vom Duodenum bis zum Rektum auftreten. Therapie der Wahl ist die Zystenresektion. Schlussfolgerungen: Mesenteriale Zysten sind seltene intraabdominale Befunde. Die definitive Diagnosesicherung und die Therapie besteht in der Resektion.


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