Aim: There are many reports about the efficacy of analgesics in reducing postoperative pain after lumbar decompressive
surgery. This study aimed to investigate the effect of subdermal and intramuscular injection of bupivacaine on the severity
of postoperative pain after lumbar decompression surgery.
Material and Methods: in this randomized double-blind trial, 50 patients who candidate for lumbar decompressive surgery
elective for this them. Bupivacaine (0.25%) in the intervention group and normal saline (40 ml) in the control group were
injected subcutaneously and intramuscularly. Factors of age, size of surgical cutting, number of operating space, duration of
operation, the rate of need to analgesia, and the severity of pain at times of 3,12 and 24 hours after surgery were assessed.
Results: The severity of pain in Bupivacaine group, in hours 3, 12 and 24 after postoperative surgery was less than control
group (P value<0.05). Also There was no significant difference between the two groups in terms of mean pain intensity
using repeated measure design (P value<0.05). But within Bupivacaine group, pain severity significantly decreased during
the 24 hours after surgery. (p<0.05)
Conclusion: Although bupivacaine (0.25%) results in reducing pain after surgery, more studies are recommended to
investigate the effect of bupivacaine in combination with other drugs in cases of lumbar decompressive surgery. Also, it
reduces pain during the 24 hours after surgery is very important.