Cutaneous CD34+ Spindle Cell Neoplasms: Histopathologic Features Distinguish Spindle Cell Lipoma, Solitary Fibrous Tumor, and Dermatofibrosarcoma Protuberans

2010 ◽  
Vol 32 (8) ◽  
pp. 764-768 ◽  
Author(s):  
Lance Wood ◽  
Thomas J Fountaine ◽  
Lorraine Rosamilia ◽  
Klaus F Helm ◽  
Loren E Clarke
Keyword(s):  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Dermatofibrosarcoma Protuberans ◽  
Spindle Cell Lipoma ◽  
Fibrous Tumor ◽  
Histopathologic Features

Fat‐forming variant of solitary fibrous tumor of the pleura, mimicking spindle cell lipoma

2019 ◽  
Vol 69 (5) ◽  
pp. 309-311 ◽  
Author(s):  
Maiko Takeda ◽  
Kensuke Kojima ◽  
Yoshihiko Taniguchi ◽  
Hyung‐Eun Yoon ◽  
Akihide Matsumura ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Fibrous Tumor

scholarly journals Dendritic Myxofibrolipoma: Often Misdiagnosed as Sarcoma

2011 ◽  
Vol 4 (3) ◽  
pp. 171-174 ◽  
Author(s):  
Awatif Y. Al-Maskery ◽  
Salem M. Al-Sidairy ◽  
Aisha S. Al-Hamadani
Keyword(s):  
Soft Tissue Tumor ◽  
Clinical Presentation ◽  
Spindle Cell ◽  
Spindle Cell Lipoma ◽  
Complete Excision ◽  
Lower Lip ◽  
Benign Soft Tissue Tumor ◽  
Proper Diagnosis ◽  
Fibrous Tumor ◽  
Combined Feature

The author describes a benign soft tissue tumor that could be easily mistaken for sarcoma. It represents a combined feature of solitary fibrous tumor and spindle cell lipoma. The clinical presentation, diagnosis, and management of this lesion are discussed. It highlights the importance of proper diagnosis to prevent unnecessary and ineffective treatment by clinicians as the complete excision of this lesion is the treatment of choice and recurrence is very unlikely. It is believed that this case is the first reported case of dendritic myxofibrolipoma occurring in the lower lip mucosa in an Omani patient.

Solitary Fibrous Tumor of the Prostate

2001 ◽  
Vol 125 (2) ◽  
pp. 274-277
Author(s):  
Michael R. Pins ◽  
Steven C. Campbell ◽  
William B. Laskin ◽  
Karen Steinbronn ◽  
Daniel P. Dalton
Keyword(s):  
Mitotic Activity ◽  
Solitary Fibrous Tumor ◽  
Growth Pattern ◽  
Spindle Cell ◽  
Cytologic Atypia ◽  
Diffuse Growth ◽  
High Mitotic Activity ◽  
Spindle Cell Tumors ◽  
Fibrous Tumor

Abstract We report 2 cases of solitary fibrous tumor of the prostate. Histologically, both tumors demonstrated a multipatterned architecture with varying degrees of collagenization and hemangiopericytoma-like foci, and both were composed of CD34-immunopositive spindled cells that insinuated themselves between strips of collagen. The tumor in case 1 was well circumscribed and showed minimal mitotic activity or pleomorphism, whereas the tumor in case 2 was more cellular, less collagenous, had a more diffuse growth pattern, and exhibited cytologic atypia and high mitotic activity. Prostatic solitary fibrous tumor must be distinguished from other spindle cell tumors reported to occur in the prostate. To our knowledge, these cases represent only the fifth and sixth reported cases of prostatic solitary fibrous tumor.

Solitary Fibrous Tumor of the Parapharyngeal Space: A Case Report and Review of the Literature

1996 ◽  
Vol 75 (10) ◽  
pp. 681-684 ◽  
Author(s):  
Kunal Gangopadhyay ◽  
Khalid Taibah ◽  
M. Babu Manohar ◽  
Hala Kfoury
Keyword(s):  
Case Report ◽  
Head And Neck ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Parapharyngeal Space ◽  
English Literature ◽  
Review Of The Literature ◽  
Solitary Fibrous Tumors ◽  
Rare Location ◽  
Fibrous Tumor

Solitary fibrous tumors are uncommon spindle cell neoplasms generally associated with serosal surfaces, especially the pleura. Recently, these tumors have been documented in a number of extrapleural sites including the head and neck. So far only two cases of parapharyngeal solitary fibrous tumor have been reported in the English literature. Rare location of an uncommon lesion often gives rise to difficulty in diagnosis or to misdiagnosis. In both the previously reported cases, as well as in our case, the diagnosis of solitary fibrous tumor was not made until the excised tumor was subjected to histopathology and immunohistochemistry.

Solitary Fibrous Tumor of the Kidney. A Propos of a Case

2009 ◽  
Vol 76 (2) ◽  
pp. 112-114 ◽  
Author(s):  
M. Marzi ◽  
M. D'Alpaos ◽  
P. Piras ◽  
A. Paiusco ◽  
M.S. Minervini ◽  
...  
Keyword(s):  
Solitary Fibrous Tumor ◽  
Renal Pelvis ◽  
Spindle Cell ◽  
Left Kidney ◽  
Clinical Behavior ◽  
Spindle Cell Neoplasm ◽  
Solitary Fibrous Tumors ◽  
Genital Apparatus ◽  
Cell Neoplasm ◽  
Fibrous Tumor

Solitary Fibrous Tumors (SFT) are rare spindle cell neoplasm that typically originate from the pleura. However, cases of the SFT are described with origin in other organs, including the urinary and genital apparatus. Within the kidney, except from the renal pelvis, only 19 cases of SFT are described and such rarity of localization makes the histogenesis and the prognosis of the tumor rather unknown. We report the case of a 72-year-old lady who attended our Unit for a mass that was clinically palpable at the level of the left hemiabdomen. The tomodensitographic test indicated a 19cm-diameter mass of likely pertinence of the middle bystender of the left kidney. She had undergone left radical nephrectomy. The histological examination highlighted a solitary fibrous tumor (SFT): the presence of hypercellularity, of cellular pleiomorphism and of a high number of mitosis has led to a histological diagnosis of malignancy for the neoplasm analyzed. The SFT are of rare clinical comparison: this does not allow for a deep knowledge of the lesion histogenesis and prognosis; moreover, the clinical behavior should be more precisely defined.

scholarly journals Solitary Fibrous Tumor of the Kidney: A Case Report

2013 ◽  
Vol 2013 ◽  
pp. 1-4
Author(s):  
Abdullah Demirtaş ◽  
Volkan Sabur ◽  
Hülya Akgün ◽  
Emre Can Akınsal ◽  
Deniz Demirci
Keyword(s):  
Solitary Fibrous Tumor ◽  
Cystic Lesion ◽  
Spindle Cell ◽  
Left Kidney ◽  
Ki 67 ◽  
Spindle Cell Neoplasm ◽  
Cell Neoplasm ◽  
Fibrous Tumor ◽  
Immunohistochemical Studies ◽  
Hmb 45

Solitary fibrous tumor is a spindle cell neoplasm mostly originating from pleura; however, it has also recently been reported to be extrapleural. A 57-year-old man presented with left lumbal pain. Ultrasonography and computed tomography showed a cystic lesion of 14 × 11 cm with solid areas and septations in middle and lower poles of the left kidney. Radical nephrectomy was performed. Immunohistochemical studies showed strong reactions with CD34 and CD99. A nuclear positivity with Ki-67 was observed in less than 1% of cells. Despite repeated stainings with vimentin, no clear tumor evaluation could be made due to artifacts. The tumor was negative with Bcl-2, desmin, HMB-45, S100, FVIII, and CD31. Histopathological and molecular studies made the diagnosis of a solitary fibrous tumor. The patient is now currently free of disease at the 26th month of followup.

scholarly journals Malignant solitary fibrous tumor of the thyroid: a case-report and review of the literature

2014 ◽  
Vol 58 (4) ◽  
pp. 402-406 ◽  
Author(s):  
Wellington Alves Filho ◽  
Renata Regina da Graça Lorencetti Mahmoud ◽  
Daniel Marin Ramos ◽  
Vergilius José Furtado de Araujo-Filho ◽  
Patricia Picciarelli de Lima ◽  
...  
Keyword(s):  
Thyroid Gland ◽  
Solitary Fibrous Tumor ◽  
Spindle Cell ◽  
Spindle Cell Neoplasm ◽  
Cellular Atypia ◽  
Long Term Follow Up ◽  
History Of ◽  
Fibrous Tumor

Solitary fibrous tumor (SFT) is an uncommon spindle-cell neoplasm that most often involves the pleura, rarely occurring in extra-thoracic locations. Twenty-six cases of SFT arising in the thyroid gland have been described. We report a case of a 60-year-old woman presenting an 8-month history of enlargement of the neck associated with dysphagia. The patient underwent a right hemithyroidectomy and SFT of the thyroid was diagnosed. Immunohistochemistry showed positivity for CD34 marker, and the high number of mitoses and the presence of cellular atypia suggested that the tumor was malignant. To our knowledge, this is the second case of malignant SFT of the thyroid gland ever reported. Due to the rarity of these tumors, the indication of adjuvant therapy and prognosis are uncertain. Long-term follow-up after surgical resection seems to be advisable.

scholarly journals Solitary Fibrous Tumor of the Sigmoid Colon Masquerading as an Adnexal Neoplasm

2016 ◽  
Vol 2016 ◽  
pp. 1-4 ◽  
Author(s):  
Laura Bratton ◽  
Rabih Salloum ◽  
Wenqing Cao ◽  
Aaron R. Huber
Keyword(s):  
Sigmoid Colon ◽  
Solitary Fibrous Tumor ◽  
High Power ◽  
Spindle Cell ◽  
Cytologic Atypia ◽  
Spindle Cell Neoplasm ◽  
Solitary Fibrous Tumors ◽  
Cell Neoplasm ◽  
Mitotic Figures ◽  
Fibrous Tumor

Solitary fibrous tumor is a rare, benign spindle cell neoplasm that was first described in the thoracic pleura. This tumor is now known to occur at many extrapleural sites. There are established criteria for the diagnosis of malignant solitary fibrous tumor including ≥4 mitotic figures per 10 high-power fields, increased cellularity, cytologic atypia, infiltrative margins, and/or necrosis. Although all solitary fibrous tumors have the potential to recur or metastasize, those with malignant histologic features tend to behave more aggressively. We report a case of solitary fibrous tumor, with malignant histologic features, in a 21-year-old woman which arose from the serosal surface of the sigmoid colon.

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