What nonpharmacologic strategies help prevent high-altitude pulmonary edema?

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sergey Ivanov
Keyword(s):  
Pulmonary Edema ◽  
High Altitude ◽  
High Altitude Pulmonary Edema

scholarly journals The Oxygen Transport Triad in High-Altitude Pulmonary Edema: A Perspective from the High Andes

2021 ◽  
Vol 18 (14) ◽  
pp. 7619
Author(s):  
Gustavo Zubieta-Calleja ◽  
Natalia Zubieta-DeUrioste
Keyword(s):  
Pulmonary Edema ◽  
High Altitude ◽  
Oxygen Transport ◽  
Acute Mountain Sickness ◽  
Breath Holding ◽  
Acid Base Balance ◽  
Initial Exposure ◽  
High Altitude Pulmonary Edema ◽  
Tolerance To Hypoxia ◽  
Dynamic Pump

Acute high-altitude illnesses are of great concern for physicians and people traveling to high altitude. Our recent article “Acute Mountain Sickness, High-Altitude Pulmonary Edema and High-Altitude Cerebral Edema, a View from the High Andes” was questioned by some sea-level high-altitude experts. As a result of this, we answer some observations and further explain our opinion on these diseases. High-Altitude Pulmonary Edema (HAPE) can be better understood through the Oxygen Transport Triad, which involves the pneumo-dynamic pump (ventilation), the hemo-dynamic pump (heart and circulation), and hemoglobin. The two pumps are the first physiologic response upon initial exposure to hypobaric hypoxia. Hemoglobin is the balancing energy-saving time-evolving equilibrating factor. The acid-base balance must be adequately interpreted using the high-altitude Van Slyke correction factors. Pulse-oximetry measurements during breath-holding at high altitude allow for the evaluation of high altitude diseases. The Tolerance to Hypoxia Formula shows that, paradoxically, the higher the altitude, the more tolerance to hypoxia. In order to survive, all organisms adapt physiologically and optimally to the high-altitude environment, and there cannot be any “loss of adaptation”. A favorable evolution in HAPE and pulmonary hypertension can result from the oxygen treatment along with other measures.

scholarly journals High‐altitude Pulmonary Edema: Review

2014 ◽  
Vol 56 (4) ◽  
pp. 235-243 ◽  
Author(s):  
Shuchi Bhagi ◽  
Swati Srivastava ◽  
Shashi Bala Singh
Keyword(s):  
Pulmonary Edema ◽  
High Altitude ◽  
High Altitude Pulmonary Edema

scholarly journals Hypoxia-Induced Inflammatory Chemokines in Subjects with a History of High-Altitude Pulmonary Edema

2015 ◽  
Vol 31 (1) ◽  
pp. 81-86 ◽  
Author(s):  
K. P. Mishra ◽  
Navita Sharma ◽  
Poonam Soree ◽  
R. K. Gupta ◽  
Lilly Ganju ◽  
...  
Keyword(s):  
Pulmonary Edema ◽  
High Altitude ◽  
High Altitude Pulmonary Edema ◽  
Inflammatory Chemokines ◽  
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