Evaluation of Mandibular Reconstruction With Particulate Cancellous Bone Marrow and Titanium Mesh After Mandibular Resection Due to Tumor Surgery

A particulate cancellous bone and marrow (PCBM) graft combined with titanium (Ti-) mesh tray has become one of the most popular mandibular reconstruction methods. The technique has been applied to the mandibular discontinuity defects after segmental mandibulectomy. To the best of our knowledge, there are no reports on using the technique after hemimandibulectomy, during which a wide mandibular resection, including the condyle, is performed. Here we report firstly a case of mandibular reconstruction after hemimandibulectomy, using a plate and soft-tissue free flap, followed by a Ti-mesh and PCBM harvested from the bilateral posterior ilia, which was successful. This case report first revealed how bone resorption occurred clinically in mandibular reconstruction using PCBM and Ti-mesh tray after hemimandibulectomy. We also revealed the high predictability of the mandibular reconstruction using PCBM and Ti-mesh tray after hemimandibulectomy. Our report also provides a guiding principle to overcome the limitation of mandibular reconstruction using PCBM and Ti-mesh tray after hemimandibulectomy. However, our manuscript has limited evidence being a case report.

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Clinical Usefulness of Mandibular Reconstruction Using Custom-Made Titanium Mesh Tray and Autogenous Particulate Cancellous Bone and Marrow Harvested From Tibia and/or Ilia

Journal of Craniofacial Surgery ◽

10.1097/scs.0000000000002472 ◽

2016 ◽

Vol 27 (3) ◽

pp. 586-592 ◽

Cited By ~ 9

Author(s):

Hiroyuki Yamada ◽

Kazutoshi Nakaoka ◽

Tomoo Sonoyama ◽

Kenichi Kumagai ◽

Tomoko Ikawa ◽

...

Keyword(s):

Cancellous Bone ◽

Mandibular Reconstruction ◽

Clinical Usefulness ◽

Titanium Mesh ◽

Custom Made

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Clinical usefulness of mandibular reconstruction using custom-made titanium mesh tray and autogenous particulate cancellous bone and marrow harvested from tibia and/or ilia

International Journal of Oral and Maxillofacial Surgery ◽

10.1016/j.ijom.2015.08.878 ◽

2015 ◽

Vol 44 ◽

pp. e168-e169

Author(s):

H. Yamada ◽

K. Nakaoka ◽

T. Sonoyama ◽

K. Kumagai ◽

T. Ikawa ◽

...

Keyword(s):

Cancellous Bone ◽

Mandibular Reconstruction ◽

Clinical Usefulness ◽

Titanium Mesh ◽

Custom Made

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Comparison of two β-tricalcium phosphate composite grafts used for reconstruction of mandibular critical size bone defects

Veterinary and Comparative Orthopaedics and Traumatology ◽

10.3415/vcot-08-04-0038 ◽

2009 ◽

Vol 22 (02) ◽

pp. 96-102 ◽

Cited By ~ 12

Author(s):

N.-C. Gellrich ◽

G. Hauschild ◽

M. Fehr ◽

K.-H. Bormann ◽

K. Rohn ◽

...

Keyword(s):

Bone Marrow ◽

Cancellous Bone ◽

Tricalcium Phosphate ◽

Mandibular Reconstruction ◽

Average Weight ◽

Tissue Quality ◽

Promising Alternative ◽

Composite Grafts ◽

Group A ◽

Group B

Summary Objective: The aim was to compare osseointegration of blood perfused β-tricalcium phosphate cylinders (β-TCPB) with similar composites that were additionally loaded with cancellous bone and bone marrow (β-TCPB/BM/CB) for mandibular reconstruction. Methods: Twelve German Black-Headed sheep with an average weight of 72.5 ± 10 kg underwent segmental re-section of the right hemi-mandible. The animals that were assigned to group A (n=6) were reconstructed using β-TCPB while the sheep that were assigned to group B received β-TCPB/BM/CB grafts. Tissue quality was histologically assessed and bone-, scaffold-, cartilage- and fibrous-tissue area were estimated using semiautomated histomorphometrical software. Results: Composite grafts that were loaded with bone marrow and cancellous bone (β-TCPB/BM/CB) exhibited significant (p<0.01) higher amounts of bone formation than β-TCPB. The patients that were assigned to group B achieved defect union and a high grade of bone maturation. Residual ceramic remnants were rare and disconnected. Bone maturity within group A was inferior and none of the specimens showed defect union. The defect centre was still occupied by a ceramic core. Clinical significance: Bone and bone marrow augmented β-tricalcium phosphate composites may qualify as a promising alternative to autograft bone for mandibular reconstruction in human and veterinary medicine.

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