scholarly journals Cycle Threshold to Test Positivity in COVID-19 for Return to Work Clearance in Health Care Workers

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Sandra Domeracki ◽  
Robert N. Clapp ◽  
Kristopher Taylor ◽  
Chuanyi M. Lu ◽  
Harry Lampiris ◽  
...  
Author(s):  
Ai Chien ◽  
Sandra Domeracki ◽  
Sandeep Guntur ◽  
Kristopher Taylor ◽  
Chuanyi M. Lu ◽  
...  

Abstract Objective Household SARS-COV-2 contact constitutes a high-risk exposure for health care workers (HCWs). Cycle threshold (Ct) of reverse transcriptase–polymerase chain reaction testing provides an estimate of COVID-19 viral load, which can inform clinical and workplace management. We assessed whether Ct values differed between HCWs with COVID-19 with and without household exposure. Methods We analyzed HCW COVID-19 cases whose Ct data could be compared. We defined low Ct at a cut-point approximating a viral load of 4.6 × 106 copies per ml. Logistic regression tested the association of household exposure and symptoms at diagnosis with a low Ct value. Results Of 77 HCWs with COVID-19, 20 were household exposures cases and 34 were symptomatic at testing (7 were both household-exposed and symptomatic at testing). Among household exposures, 9 of 20 (45%) manifested lower Ct values compared to 14 of 57 (25%) for all others. In a bivariate model, household exposure was not statistically associated with lower Ct (Odds Ratio [OR] 1.20; 95% Confidence Interval [CI] 0.97–1.51). In multivariable modelling both household exposure (OR] 1.3; 95% CI 1.03–1.6) and symptoms at diagnosis (OR 1.4; 95% CI 1.15–1.7) were associated with a low Ct value. Discussion Household exposure in HCWs with newly diagnosed COVID-19 was associated with lower Ct values, consistent with a higher viral load, supporting the hypothesis that contracting COVID-19 in that manner leads to a greater viral inoculum.


2013 ◽  
Vol 70 (Suppl 1) ◽  
pp. A107.3-A107
Author(s):  
C S Serra ◽  
Vargas-Prada ◽  
Mirabent ◽  
Villar ◽  
Ramada ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jaime Villarreal ◽  
Sandra Valeria Nieto ◽  
Fabián Vázquez ◽  
M. Teresa del Campo ◽  
Ignacio Mahillo ◽  
...  

2021 ◽  
Vol 9 (8) ◽  
pp. 368-381
Author(s):  
Dr Juhaina Abdulrahiem ◽  
Marwa Zakaria ◽  
Isalam Mohammad ◽  
Hassan Abdullah ◽  
Hala Amer ◽  
...  

This study about Factors that delay return to work of COVID-19 positive health care workers at King Saud medical city Riyadh Saudi Arabia.2020 Coronaviruses (CoV) are a large family of RNA viruses that cause illnesses ranging from the common cold to more severe diseases such as Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV). The aim of this study is to determine the factors that delay return to return to work among COVID-19 positive HCPs also to study the relationship of the associated risk factors and the delay in return to work among positive COVID-19 HCPs and to minimize the delay in return to work among COVID-19 positive HCPs which will maintain staffing levels to provide adequate care to all patients. Health care professional is defined as all staff in the health care facility involved in the provision of care for a COVID-19 infected patient, including those who have been present in the same area as the patient, as well as those who may not have provided direct care to the patient, but who have had contact with the patient’s body fluids, potentially contaminated items or environmental surfaces. Sampling method: The design of the sampling for this study will be Stratified Random Sampling (StRS) cross section study. This study about Factors that delay return to work of COVID-19 positive health care workers at King Saud medical city Riyadh Saudi Arabia mc.2020 Coronaviruses (CoV) are a large family of RNA viruses that cause illnesses ranging from the common cold to more severe diseases such as Middle East respiratory syndrome (MERS-CoV) and severe acute respiratory syndrome (SARS-CoV). The aim of this study is to determine the factors that delay return to return to work among COVID-19 positive HCPs also to study the relationship of the associated risk factors and the delay in return to work among positive COVID-19 HCPs and to minimize the delay in return to work among COVID-19 positive HCPs which will maintain staffing levels to provide adequate care to all patients. Health care professional is defined as all staff in the health care facility involved in the provision of care for a COVID-19 infected patient, including those who have been present in the same area as the patient, as well as those who may not have provided direct care to the patient, but who have had contact with the patient’s body fluids, potentially contaminated items or environmental surfaces. Sampling method: The design of the sampling for this study will be Stratified Random Sampling (STRS) cross section study will use SPSS to analysis.


2013 ◽  
Author(s):  
Jane Lipscomb ◽  
Jeanne Geiger-Brown ◽  
Katherine McPhaul ◽  
Karen Calabro

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