Intracranial tumours represent about 2% of all cancers. There are no known risk factors apart from prior irradiation to the skull and brain and a few rare neurogenetic syndromes, e.g. neurofibromatosis, von Hippel–Lindau syndrome, Li–Fraumeni syndrome. They may be intrinsic or extrinsic, which determines potential resectability. Neuroepithelial tumours (predominantly gliomas) account for 50 to 60% of all primary tumours. Recent discovery of ...