scholarly journals Prognostic Value of the Sum of Metabolic Tumor Volume of Primary Tumor and Lymph Nodes Using 18F-FDG PET/CT in Patients With Cervical Cancer

Medicine ◽  
2016 ◽  
Vol 95 (9) ◽  
pp. e2992 ◽  
Author(s):  
Jin Hwa Hong ◽  
Kyung Jin Min ◽  
Jae Kwan Lee ◽  
Kyeong A So ◽  
Un Suk Jung ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Lymph Nodes ◽  
Primary Tumor ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Influence of 18F-FDG-PET/CT on staging of cervical cancer

2019 ◽  
Vol 58 (01) ◽  
pp. 17-22
Author(s):  
Paulina Cegla ◽  
Bartosz Urbanski ◽  
Ewa Burchardt ◽  
Andrzej Roszak ◽  
Witold Cholewinski
Keyword(s):  
Cervical Cancer ◽  
Lymph Nodes ◽  
Primary Tumor ◽  
Fdg Pet ◽  
Treatment Plan ◽  
Radical Change ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Figo Classification

Abstract Aim Cervical cancer is one of the most common cancers of the female reproductive system. The aim of the study was to assess the usefulness of the 18F-FDG-PET/CT study in staging of cervical cancer, with focus on the primary tumor parameters. Material & Methods 105 patients (mean age 56 ± 11y) with newly diagnosed cervical cancer underwent PET/CT examination which was performed 60 min after IV injection of 18F-FDG with a mean activity of 364 ± 75MBq. 68 patients were diagnosed with stage IIIA/IIIB, 19 patients with IIB, 10 patients with IB, 8 patients with stage IVA/IVB. Wilcoxon-Mann-Whitney test and ROC curves were used for statistical analysis. Results In 35 cases 18F-FDG-PET/CT did not show active proliferative process outside the cervix. In 38 cases metastases were found in iliac lymph nodes and in 32 patients scans showed metastases above the aortic bifurcation including lymph nodes and other organs. The largest volumes of primary tumor occurred in patients with distant metastases, while the lowest in patients with disease limited only to cervix. In 63 % of the patients PET/CT result was compatible with FIGO classification, in 20 % patients PET/CT result showed less advanced disease and in 17 % of the patients PET/CT results were higher than FIGO classification. Conclusion PET/CT using 18F-FDG has an important impact on the assessment of the stage of cervical cancer. In over 30 % of patients, this study resulted in a radical change in the treatment plan.

Prognostic value of preoperative metabolic tumor volume measured by 18F-FDG PET/CT and MRI in patients with endometrial cancer

2013 ◽  
Vol 130 (3) ◽  
pp. 446-451 ◽  
Author(s):  
Hyun Hoon Chung ◽  
Inki Lee ◽  
Hee Seung Kim ◽  
Jae Weon Kim ◽  
Noh-Hyun Park ◽  
...  
Keyword(s):  
Endometrial Cancer ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Ct And Mri

Prognostic value of metabolic tumor volume measured by FDG-PET/CT in patients with cervical cancer

2011 ◽  
Vol 120 (2) ◽  
pp. 270-274 ◽  
Author(s):  
Hyun Hoon Chung ◽  
Jae Weon Kim ◽  
Kyung Hee Han ◽  
Jae Seon Eo ◽  
Keon Wook Kang ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Pet Ct ◽  
Fdg Pet Ct

scholarly journals Prognostic Value of Metabolic Tumor Volume Measured by 18F-FDG PET/CT in Esophageal Cancer Patients

2014 ◽  
Vol 23 (1) ◽  
pp. 12-15 ◽  
Author(s):  
Çiğdem Soydal ◽  
Cabir Büte Yüksel ◽  
Özlem N. Küçük ◽  
İlker Ökten ◽  
Elgin Özkan ◽  
...  
Keyword(s):  
Esophageal Cancer ◽  
Cancer Patients ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Prognostic value of metabolic tumor volume and total lesion glycolysis assessed by 18F-FDG PET/CT in endometrial cancer

2019 ◽  
Vol 40 (11) ◽  
pp. 1099-1104
Author(s):  
Mehmet Erdogan ◽  
Evrim Erdemoglu ◽  
Şehnaz Evrimler ◽  
Candost Hanedan ◽  
Sevim S. Şengül
Keyword(s):  
Endometrial Cancer ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Metabolic Tumor Volume ◽  
Total Lesion Glycolysis ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Use of 18F-FDG PET/CT Imaging for Radiotherapy Target Volume Delineation after Induction Chemotherapy and for Prognosis of Locally Advanced Squamous Cell Carcinoma of the Head and Neck

Medicina ◽  
2018 ◽  
Vol 54 (6) ◽  
pp. 107
Author(s):  
Viktoras Rudžianskas ◽  
Erika Korobeinikova ◽  
Milda Rudžianskienė ◽  
Evelina Jaselskė ◽  
Diana Adlienė ◽  
...  
Keyword(s):  
Primary Tumor ◽  
Fdg Pet ◽  
Prognostic Value ◽  
Tumor Volume ◽  
Locally Advanced ◽  
Advanced Squamous Cell Carcinoma ◽  
Percentage Decrease ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Background and objectives: Induction chemotherapy (ICT) before definitive chemoradiation (CRT) gives high response rates in locally advanced squamous cell carcinoma of the head and neck (LA-SCCHN). However, pre-ICT gross tumor volume (GTV) for radiotherapy (RT) planning is still recommended. As 18F-FDG PET/CT has an advantage of biological tumor information comparing to standard imaging methods, we aimed to evaluate the feasibility of 18F-FDG PET/CT-based post-ICT GTV delineation for RT planning in LA-SCCHN and to assess the prognostic value of PET parameters: maximum standardized uptake value (SUVmax), metabolic tumor volume (MTV) and total lesion glycolysis (TLG). Methods: 47 LA-SCCHN patients were treated with 3 cycles of ICT (docetaxel, cisplatin, and 5-fluorouracil) followed by CRT (70 Gy in 35 fractions with weekly cisplatin). Pre- and post-ICT PET/CT examinations were acquired. Planning CT was co-registered with post-ICT PET/CT and RT target volumes were contoured according to post-ICT PET. Post-ICT percentage decrease of SUVmax, MTV and TLG in primary tumor and metastatic regional lymphnodes (LN) was counted. Loco-regional failure patterns, 3-year progression free (PFS) and overall survival (OS) were evaluated. Results: 3-year PFS and OS rates for study population were 67% and 61% respectively. 31.9% of patients progressed loco-regionally. All progress was localized in high-to-intermediate dose (60–70 Gy) RT volumes and none in low dose (50 Gy) volumes. Decrease of SUVmax ≥ 74% (p = 0.04), MTV ≥ 68% (p = 0.03), TLG ≥ 76% (p = 0.03) in primary tumor, and LN TLG decrease ≥ 74% (p = 0.03) were associated with PFS. Decrease of primary tumor SUVmax ≥ 74% (p = 0.04), MTV ≥ 69% (p = 0.03), TLG ≥ 74% (p = 0.02) and LN TLG ≥ 73% (p = 0.02) were prognostic factors for OS. Conclusions: According to our results, 18F-FDG PET/CT-based post-ICT GTV delineation is feasible strategy without negative impacts on loco-regional control and survival. Percentage decrease of metabolic PET parameters SUVmax, MTV and TLG has a prognostic value in LA-SCCHN.

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