scholarly journals Is the combined application of both drain-clamping and tranexamic acid superior to the single use of either application in patients with total-knee arthroplasty?

Medicine ◽  
2018 ◽  
Vol 97 (36) ◽  
pp. e11573 ◽  
Author(s):  
Yan-hong Han ◽  
He-tao Huang ◽  
Jian-ke Pan ◽  
Ling-feng Zeng ◽  
Gui-hong Liang ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Knee Arthroplasty ◽  
Combined Application ◽  
Total Knee ◽  
Single Use ◽  
Drain Clamping

scholarly journals Effects of Tranexamic Acid and Drain Clamping Method on Post-operative Blood Loss in Total Knee Arthroplasty

2010 ◽  
Vol 59 (1) ◽  
pp. 187-190
Author(s):  
Tateki Segata ◽  
Takeshi Yamashita ◽  
Katsuya Iwamoto ◽  
Kensuke Yonemura ◽  
Issei Ishii
Keyword(s):  
Total Knee Arthroplasty ◽  
Blood Loss ◽  
Tranexamic Acid ◽  
Knee Arthroplasty ◽  
Operative Blood Loss ◽  
Total Knee ◽  
Drain Clamping

Risk of Deep Venous Thrombosis in Drain Clamping With Tranexamic Acid and Carbazochrome Sodium Sulfonate Hydrate in Total Knee Arthroplasty

2012 ◽  
Vol 27 (1) ◽  
pp. 105-108 ◽  
Author(s):  
Tomohiro Onodera ◽  
Tokifumi Majima ◽  
Naohiro Sawaguchi ◽  
Yasuhiko Kasahara ◽  
Takayuki Ishigaki ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Venous Thrombosis ◽  
Deep Venous Thrombosis ◽  
Knee Arthroplasty ◽  
Sodium Sulfonate ◽  
Total Knee ◽  
Drain Clamping

scholarly journals Optimal Release Timing of Temporary Drain Clamping to Reduce Postoperative Bleeding After Total Knee Arthroplasty With an Intraarticular Injection of Tranexamic Acid

2021 ◽  
Author(s):  
Myung Ku Kim ◽  
Sang Hyun Ko ◽  
Yoon Cheol Nam ◽  
Yoon Sang Jeon ◽  
Won Hwan Kwon ◽  
...  
Keyword(s):  
Total Knee Arthroplasty ◽  
Tranexamic Acid ◽  
Knee Arthroplasty ◽  
Postoperative Bleeding ◽  
Intraarticular Injection ◽  
Wound Complications ◽  
Transfusion Rate ◽  
Vein Thrombosis ◽  
Total Knee ◽  
Drain Clamping

Abstract Background: Intraarticular injection of tranexamic acid (IA-TXA) plus drain-clamping is a preferred method of reducing bleeding after total knee arthroplasty (TKA). However, no consensus had been reached regarding the timing of clamping. The purpose of this study was to determine the optimum duration of drain-clamping after TKA with IA-TXA.Methods: We retrospectively reviewed 151 patients that underwent unilateral TKA with IA-TXA plus drain-clamping for 30 minutes (Group A, 60 patients), 2 hours (Group B, 42 patients), or 3 hours (Group C, 49 patients). Total drained volumes, hematocrit (Hct) reductions, estimated blood losses (EBLs), transfusion rates, and wound complications were reviewed.Results: Mean total drained volume, Hct reduction, EBL, and transfusion rate were significantly less in group C than in groups A or B (p < 0.01). No significant intergroup difference was found for wound-related complications. No surgical site infection or deep vein thrombosis was observed.Conclusion: IA-TXA plus drain-clamping for 3 hours is optimal for reducing blood loss with minimal complications after TKA.

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