Assessment of left ventricular dyssynchrony in patients with coronary artery disease during adenosine stress using ECG-gated myocardial perfusion single-photon emission computed tomography

2010 ◽  
Vol 31 (10) ◽  
pp. 864-873 ◽  
Author(s):  
Miki Horigome ◽  
Kyohei Yamazaki ◽  
Uichi Ikeda
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Left Ventricular Dyssynchrony ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Myocardial Perfusion Single Photon ◽  
Single Photon Emission Computed ◽  
Artery Disease ◽  
Photon Emission Computed Tomography

P606High intermodality variability in ejection fraction measured by echocardiography, cardiac magnetic resonance and single photon emission computed tomography in chronic coronary artery disease patients

2019 ◽  
Vol 40 (Supplement_1) ◽  
Author(s):  
T M Stokke ◽  
S I Sarvari ◽  
A W Bjerring ◽  
K H Haugaa ◽  
M T Elahi ◽  
...  
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Left Ventricular ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Chronic Coronary Artery Disease ◽  
Single Photon Emission Computed ◽  
Artery Disease ◽  
Dimensional Echocardiography ◽  
Photon Emission Computed Tomography

Abstract Background Clinical treatment strategies are often based on measurement of left ventricular ejection fraction (LVEF). There is limited evidence about variations in LVEF when measured by different imaging modalities. Purpose To investigate the intermodality variability of LVEF measured by two-dimensional echocardiography (2DE), three-dimensional echocardiography (3DE), cardiac magnetic resonance (CMR), and single photon emission computed tomography (SPECT) in patients with chronic coronary artery disease (CAD). Methods Patients from a multicenter study (DOPPLER-CIP – Determining optimal noninvasive parameters for the prediction of left ventricular remodeling in chronic ischemic patients) with chronic CAD were included. LVEF was measured by CMR and at least one additional modality. In each modality, LVEF was measured by a core laboratory independently of the other modalities. Measurements of LVEF by CMR were compared to 2DE, 3DE and SPECT using correlation and Bland-Altman plots. Results A total of 343 patients were included. Mean age was 63.9±8.3 years and 253 (74%) were males. Mean LVEF by CMR was 61.8±11.6%. Correlations between CMR LVEF and other modalities were moderate for 2DE and 3DE, and good for SPECT (Figure A-C). CMR had significantly greater correlation to SPECT, compared to 2DE and 3DE. Bland-Altman plots indicated relatively wide limits of agreement between all modalities, ranging from 31% to 42% (Figure, D-F). Mean absolute difference of LVEF between CMR and other modalities were 8.5% for 2DE, 9.0% for 3DE, and 8.3% for SPECT. The percentage of measurements that fell within a range of 5% difference compared to CMR LVEF was 41% for 2DE, 34% for 3DE and 37% for SPECT (all p>0.05). Conclusions In a multicenter study with chronic CAD patients, LVEF assessed by CMR had better correlation to SPECT, compared to 2DE and 3DE. However, there was considerable variability among all three modalities that were compared to CMR. Awareness of these variations are important in clinical management.

Image Artifacts

2015 ◽  
Author(s):  
E. Gordon DePuey
Keyword(s):  
Single Photon ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Single Photon Emission ◽  
Normal Variants ◽  
Myocardial Perfusion Single Photon ◽  
Test Specificity ◽  
Single Photon Emission Computed ◽  
Artery Disease ◽  
Photon Emission Computed Tomography

Artifacts and normal variants are a significant source of false-positive interpretations of myocardial perfusion single-photon emission computed tomography (SPECT). This chapter discusses how, by anticipating and recognizing such findings, the astute technologist and interpreting physician can increase test specificity in the diagnosis of coronary artery disease and avoid unnecessary catheterization of normal patients.

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