Discussion: Potential of Tissue-Engineered and Artificial Dermis Grafts for Fingertip Reconstruction

2020 ◽  
Vol 146 (5) ◽  
pp. 1096-1098
Author(s):  
Steven L. Henry
2020 ◽  
Vol 146 (5) ◽  
pp. 1082-1095 ◽  
Author(s):  
Sik Namgoong ◽  
Jae Eun Jung ◽  
Seung-Kyu Han ◽  
Seong-Ho Jeong ◽  
Eun-Sang Dhong

2003 ◽  
Vol 11 (5) ◽  
pp. 368-374 ◽  
Author(s):  
Sang Bong Lee ◽  
Hyun Wook Jeon ◽  
Young Woo Lee ◽  
Seong Kwan Cho ◽  
Young Moo Lee ◽  
...  

1992 ◽  
Vol 90 (6) ◽  
pp. 1009-1021 ◽  
Author(s):  
Yuichi Hirase ◽  
Tadao Kojima ◽  
Shintaro Matsuura

2003 ◽  
Vol 33 (2) ◽  
pp. 289 ◽  
Author(s):  
Min-Jeong Kim ◽  
Hyun-Ju Chung ◽  
Ok-Su Kim ◽  
Young-Joon Kim

2020 ◽  
Vol 1 (2) ◽  
pp. 76-83
Author(s):  
Wataru Kamei ◽  
Hiroki Yago ◽  
Kousuke Morioka ◽  
Hiroyuki Sakurai

2011 ◽  
Vol 57 (7) ◽  
pp. 394-400 ◽  
Author(s):  
Junichiro TAKEUCHI ◽  
Masahiro UMEDA ◽  
Maho MURATA ◽  
Yasumasa KAKEI ◽  
Akira KIMOTO ◽  
...  

2014 ◽  
Vol 66 (1) ◽  
pp. 173-178
Author(s):  
Hongqi Liu ◽  
Yan Li ◽  
Deqian Sha

The aim of this paper was to evaluate the effect of using artificial dermis matrix plus autologous split-thickness skin (ADM and ASTS) in the treatment of deep-burns in hands of severely burned patients?We recruited a total of 58 patients with large area burns greater than 80% that were eschar-excised. Twenty-eight of them were treated with ADM and ASTS (test group); 30 were treated with autologous medium-thickness skin (AMTS) (control group). The healing time of the hand wound was noted, clinical and photographic evaluations were performed, and a Jebsen-Taylor hand function test was compared and analyzed in the two groups. The wound healing time in the test group (24.22?3.34 days) were longer than that of the control group (13.42?3.36 days) and statistically significant. The healing time of skin graft donor sites was shorter than that of the control group (7.14?1.63 vs. 14.28?2.37 days) and statistically significant (P<0.05). The 3rd and 6th month follow-up with clinical and functional evaluations revealed no differences between the two groups. In addition, there was no obvious scar formation and less pigmentation in either group. The repair of deeply burned hands with artificial dermis matrix was beneficial to both wound healing and the donor site, and was beneficial to the whole body rehabilitation of severely burned patients.


2020 ◽  
Vol 2020 ◽  
pp. 1-7
Author(s):  
Fedele Lembo ◽  
Liberato Roberto Cecchino ◽  
Domenico Parisi ◽  
Aurelio Portincasa

Radical ablative surgery is the gold standard treatment of head skin cancer. The authors expose their experience with a new artificial dermis (Pelnac®), analyzing retrospectively the overall morbidity and aesthetic outcomes. 16 consecutive patients underwent two surgical procedures under local anesthesia. The first involved the tumor removal and application of the ADM. In the second, the exposed tissue was covered with a split-thickness skin graft. On follow-up (6 months), tumor recurrences, quality of scars (using the Vancouver Scar Scale), and patient reported outcomes (using FACE-Q Skin Cancer Module) were evaluated. 10 were males and 6 females, with a mean age of 73 years (61–89). The follow-up ranged from 12 to 48 months (mean: 30). The sites of skin tumor were scalp (12 cases), forehead (2), cheek (1), and zygomatic area (1). Nine patients underwent previous local surgery; two received radiotherapy. The average length of hospital stay was 3.2 days. The mean surface area of the defect was 59.15 cm2 (16.9–89.5). In three cases, the surgical bed was bone without periosteum. The malignant tumors excised were basal cell carcinoma (68.75%), squamous cell carcinoma (18.75%), malignant melanoma (6.25%), and sarcoma (6.25%). The mean operating time was 41 minutes for the first operation (25–55) and 34 for the second (25–48). No significant problems were observed and 15 patients (93.75%) had 100 percent intake of graft. The mean time of healing was 39 days (32–45). At 6 months post-op, no tumor recurrence. Satisfactory cosmetic and functional results were obtained in all patients as shown by the VSS Scale and FACEQ skin cancer module mean scores. We believe that the artificial dermis is a reliable alternative to flaps and should be considered an excellent option in head reconstruction for skin cancer, especially in critical patients (old, with large and deep defects, with recurrent tumors, required radiotherapy).


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