Reliability of Quantitative 18F-FDG PET/CT Imaging Biomarkers for Classifying Early Response to Chemoradiotherapy in Patients With Locally Advanced Non–Small Cell Lung Cancer

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Kevin P. Horn ◽  
Hannah M.T. Thomas ◽  
Hubert J. Vesselle ◽  
Paul E. Kinahan ◽  
Robert S. Miyaoka ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Fdg Pet ◽  
Locally Advanced ◽  
Early Response ◽  
Small Cell ◽  
Imaging Biomarkers ◽  
Small Cell Lung ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Early Response Assessment to Targeted Therapy Using 3′-deoxy-3′[(18)F]-Fluorothymidine (18F-FLT) PET/CT in Lung Cancer

Diagnostics ◽  
2020 ◽  
Vol 10 (1) ◽  
pp. 26 ◽  
Author(s):  
Kalevi Kairemo ◽  
Elmer B. Santos ◽  
Homer A. Macapinlac ◽  
Vivek Subbiah
Keyword(s):  
Lung Cancer ◽  
Targeted Therapy ◽  
Fdg Pet ◽  
Early Response ◽  
Small Cell ◽  
Small Cell Lung ◽  
Flt Pet ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

Although 2-deoxy-2-[18F]-fluoro-D-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) is a sensitive nuclear medicine modality, specificity for characterizing lung cancer is limited. Tumor proliferation and early response to molecularly targeted therapy could be visualized using 3′-deoxy-3′[(18)F]-fluorothymidine (18F-FLT) PET/CT. The superiority of 18F-FLT PET/CT over 18F-FDG PET/CT in early therapeutic monitoring has been well described in patients after chemotherapy, radiotherapy, and/or chemo/radiotherapy. In thispilot study, we explorethe use of 18F-FLT PET/CT as an early response evaluation modality in patients with lung cancerand provide specific case studies of patients with small cell lung cancer and non-small cell lung cancer who received novel targeted therapies. Early response for c-MET inhibitor was observed in four weeks and for MDM2 inhibitor in nine days.

Impact of preoperative 18F-FDG PET/CT on survival of resected mono-metastatic non-small cell lung cancer

Lung Cancer ◽  
2016 ◽  
Vol 93 ◽  
pp. 28-34 ◽  
Author(s):  
Simone Tönnies ◽  
Mario Tönnies ◽  
Jens Kollmeier ◽  
Torsten T. Bauer ◽  
Gregor J. Förster ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Small Cell ◽  
Small Cell Lung ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Comparison of 18F-FDG PET/CT and MDCT for staging/restaging of non-small cell lung cancer

Neoplasma ◽  
2015 ◽  
Vol 62 (02) ◽  
pp. 295-301 ◽  
Author(s):  
D. SOBIC-SARANOVIC ◽  
I. PETRUSIC ◽  
V. ARTIKO ◽  
S. PAVLOVIC ◽  
D. SUBOTIC ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Small Cell ◽  
Small Cell Lung ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Multifunctional Profiling of Non-Small Cell Lung Cancer Using 18F-FDG PET/CT and Volume Perfusion CT

2012 ◽  
Vol 53 (4) ◽  
pp. 521-529 ◽  
Author(s):  
A. W. Sauter ◽  
S. Winterstein ◽  
D. Spira ◽  
J. Hetzel ◽  
M. Schulze ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Small Cell ◽  
Perfusion Ct ◽  
Small Cell Lung ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct

scholarly journals Correlation between Semi-Quantitative 18F-FDG PET/CT Parameters and Ki-67 Expression in Small Cell Lung Cancer

2016 ◽  
Vol 50 (1) ◽  
pp. 24-30 ◽  
Author(s):  
Soyeon Park ◽  
Eunsub Lee ◽  
Seunghong Rhee ◽  
Jaehyuk Cho ◽  
Sunju Choi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Fdg Pet ◽  
Small Cell ◽  
Small Cell Lung ◽  
Ki 67 ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct
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