Bone Tuberculous Granulomatous Inflammation Mimicking Malignancy on 68Ga-FAPI PET/CT

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Weidong Gong ◽  
Xiao Yang ◽  
Chunru Mou ◽  
Huipan Liu ◽  
Chunyin Zhang
Keyword(s):  
Granulomatous Inflammation ◽  
Pet Ct

Sarcoidosis and Sarcoid Reactions in Endometrial Cancer Cases Masquerading Advanced Stage Malignancy

2021 ◽  
Vol 17 ◽  
Author(s):  
Serkan Akis ◽  
Canan Kabaca ◽  
Esra Keles ◽  
Handan Cetiner ◽  
Hatice Akay
Keyword(s):  
Endometrial Cancer ◽  
Lymph Nodes ◽  
Inflammatory Diseases ◽  
Uterine Cavity ◽  
Standardized Uptake Value ◽  
Granulomatous Inflammation ◽  
Pathological Examination ◽  
Pet Ct ◽  
Granulomatous Lesions ◽  
Granulomatous Lymphadenitis

Background: Sarcoidosis is usually diagnosed by ruling out other granulomatous inflammatory diseases. Rarely, it may be suspected with a pathological examination after surgical intervention for another disease. The sarcoid reaction is noninfectious granulomatous lymphadenitis which can occur at nodes draining a neoplasm. We demonstrated granulomatous lesions masquerading metastasis by Positron Emission Tomography/Computed Tomography (PET/CT) in endometrial cancer. We presented two cases of endometrial cancer with sarcoidosis and sarcoid-like reactions because of their challenging clinical and radiological findings. Cases: In case 1, there was diffuse granulomatous inflammation (no metastasis) in lymph nodes (n=92) and giant cells containing calcifications (Schaumann bodies). In case 2, PET/CT revealed hypermetabolism with malignancy suspicion in the pelvic lymph nodes (maximum standardized uptake value= 13) and pathological evaluation reported a 4.5 cm tumor within the uterine cavity without any nodal metastasis. Results: PET/CT has no role in the evaluation of differential diagnosis between granulomatous lymphadenitis and metastatic disease. Conclusions: Granulomatous lesions might mimic the metastasis of coexisting malignant diseases.

scholarly journals Simultaneous use of FDG-18 and 68Ga-citrate PET/CT for the differential diagnosis of sarcoidosis and malignant disease

2020 ◽  
Vol 90 (3) ◽  
Author(s):  
Cuneyt Tetikkurt ◽  
Haluk Sayman ◽  
Selin Ece Dedeoglu ◽  
Bahar Kubat ◽  
Seza Tetikkurt
Keyword(s):  
Fdg Pet ◽  
Malignant Disease ◽  
Pulmonary Function Tests ◽  
Granulomatous Inflammation ◽  
Final Diagnosis ◽  
Middle Lobe ◽  
Pet Ct ◽  
18F Fdg ◽  
Simultaneous Use ◽  
The Right

A 67-year-old male presented with cutaneous rash, lassitude and fatigue of three weeks. Personal history included psoriasis and sarcoidosis. Physical examination revealed macular rash on the anterior chest wall. Laboratory results were within normal limits. Chest X-ray showed normal findings. Pulmonary function tests demonstrated a mild obstructive pattern and a mild decrease in DLCO/VA. Thorax CT revealed two nodules in the right upper and middle lobe. 68Ga-citrate PET/CT did not demonstrate any active inflammatory reaction associated with sarcoidosis while 18F-FDG PET/CT revealed increased FDG uptake in the right middle lobe, upper division bronchus and in the left lower abdominal quadrant. Histopathologic examination of the colon biopsy was compatible with adenocarcinoma and bronchoscopic biopsy of the lung lesions revealed nonspecific granulomatous inflammation. BAL cytology was normal while BAL culture did not grow any pathologic organisms. Simultaneous use of 18F-FDG and 68Ga-citrate PET/CT was the hallmark for the final diagnosis in our patient. While FDG/PET has detected the pulmonary and colonic malignant foci in our patient, 68Ga-citrate PET/CT excluded the presence of active granulomatous inflammation of sarcoidosis. Simultaneous utility of these two imaging modalities in patients with sarcoidosis is of great importance in terms of guiding the clinician towards the accurate diagnostic pathway which is the hallmark for final diagnosis, especially in the presence of concomitant malignant disease.

Orbital Granulomatous Inflammation Mimicking Malignancy on 68Ga-FAPI PET/CT

2022 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Yong Wang ◽  
Xiao Yang ◽  
Min Tian ◽  
Hongbin Lv ◽  
Huipan Liu
Keyword(s):  
Granulomatous Inflammation ◽  
Pet Ct

scholarly journals Disseminated Bartonella henselae Infection Visualized by [18F]FDG-PET/CT and MRI

Diagnostics ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 25 ◽  
Author(s):  
Marie Norredam ◽  
Andreas Knudsen ◽  
Carsten Thomsen ◽  
Lothar Wiese
Keyword(s):  
Fdg Pet ◽  
Bartonella Henselae ◽  
Granulomatous Inflammation ◽  
Unknown Origin ◽  
Complete Recovery ◽  
Intravenous Contrast ◽  
Pet Ct ◽  
18F Fdg ◽  
Fdg Pet Ct ◽  
Ct And Mri

We describe the clinical course of a 24-year old male with Crohn’s disease in immunosuppressive therapy admitted with a 6-week history of fever, weight loss, night sweat, and general malaise. The patient received extensive workup for a fever of unknown origin and received empiric antibiotics. Workup with Fluorine-18 fluoro-2-deoxy-d-glucose ([18F]FDG) positron-emission tomography (PET/CT), and magnetic resonance imaging (MRI) with intravenous contrast showed multifocal ostitis of the columna and os sacrum, as well as abscesses in m. iliopsoas and m. iliacus and affection of the retroperitoneum, liver, and spleen. Initially, malignancy was suspected, but a subsequent liver biopsy showed necrotizing granulomatous inflammation and a later polymerase chain reaction (PCR) showed Bartonella henselae. The patient had relevant exposure from housecats. He was treated with Doxycycline and Rifampicin for 12 weeks resulting in complete recovery. This case is, to our knowledge, a rare example of disseminated infection with Bartonella henselae visualized on both [18F]FDG-PET/CT and MRI.

Chronic Nonspecific Granulomatous Inflammation of the Stomach, Duodenum and Intestine

1955 ◽  
Vol 29 (3) ◽  
pp. 358-369 ◽  
Author(s):  
Alexander Richman ◽  
Herman D. Zeifer ◽  
Asher Winkelstein ◽  
Paul A. Kirsciiner ◽  
Roger D. Steinhardt
Keyword(s):  
Granulomatous Inflammation

1596: Lymph Node Staging in Prostate Cancer by the use of 11C-CHOLIN-PET/CT Scan Imaging

2005 ◽  
Vol 173 (4S) ◽  
pp. 432-432
Author(s):  
Georg C. Bartsch ◽  
Norbert Blumstein ◽  
Ludwig J. Rinnab ◽  
Richard E. Hautmann ◽  
Peter M. Messer ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Lymph Node ◽  
Ct Scan ◽  
Lymph Node Staging ◽  
Pet Ct ◽  
Pet Ct Scan

Diese unglaubliche Müdigkeit und immer wieder abends Fieber und Kopfschmerzen

Praxis ◽  
2017 ◽  
Vol 106 (19) ◽  
pp. 1061-1064
Author(s):  
Katharina Brodsky ◽  
Dominique Oberlin ◽  
Reto Nüesch
Keyword(s):  
Sich Eine ◽  
Pet Ct

Zusammenfassung. Wir berichten über einen 58-jährigen Patienten mit seit Monaten bestehender B-Symptomatik, rezidivierenden Fieberschüben begleitet von Kopfschmerzen und erhöhten Entzündungsparametern. In der Erstlinienabklärung ergaben sich keine eindeutigen Hinweise auf eine infektiologische oder rheumatologische Ursache, auffällig war lediglich eine mediastinale und hiläre Lymphadenopathie. Zum Ausschluss eines Malignoms wurde eine PET-CT durchgeführt, in der sich eine FDG-Aufnahme im Bereich der grossen Gefässe zeigte, passend zu einer Riesenzellarteritis. Bei eindeutigem Befund konnte auf einen Temporalarterienbiopsie verzichtet und eine Therapie mit Glukokortikoiden begonnen werden.

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