Consideration of KRAS Mutational Status May Enhance the Prognostic Impact of Indeterminate Extrahepatic Disease in the Lungs, as Identified by 18FDG-PET Scan, in Patients With Colorectal Liver Metastases

2018 ◽  
Vol 268 (1) ◽  
pp. e8-e9
Author(s):  
Georgios A. Margonis ◽  
Nikolaos Andreatos ◽  
Timothy M. Pawlik ◽  
Matthew J. Weiss
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Pet Scan ◽  
Extrahepatic Disease ◽  
Prognostic Impact ◽  
18Fdg Pet ◽  
Mutational Status

scholarly journals In Colorectal Liver Metastases, the Presence of Extrahepatic Disease Correlates with the Pathology of the Primary Tumour

ISRN Oncology ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-5
Author(s):  
Saleh Abbas ◽  
Vincent Lam
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Primary Tumour ◽  
False Negative ◽  
Pet Scan ◽  
Colorectal Metastases ◽  
Extrahepatic Disease ◽  
Westmead Hospital ◽  
Fdg Pet Scan ◽  
Extrahepatic Metastases

Background. FDG-PET scan detects extrahepatic metastases in 20% of patients with colorectal liver metastases but it is reported to have approximately 16% false negative rates. Patients and Methods. Patients who had PET scan for metastatic colorectal cancer at Westmead Hospital between March 2006 and March 2010 were reviewed retrospectively. The results of PET scan were correlated with tumour characteristics that were thought to affect the overall prognosis. Results. Degree of tumour differentiation and vascular invasion were significantly predictive for the presence of extrahepatic disease on PET scan, also did the level of CEA. Conclusion. The detection of extrahepatic disease in colorectal liver metastases correlates with the biologic behaviour of the primary tumour. Poorly differentiated tumours and those with lymphovascular invasion behave in aggressive fashion and likely to have wide-spread metastases. This should be considered when contemplating liver resection for colorectal metastases.

Prognostic Relevance of KRAS Mutational Status in Patients with Resectable Colorectal Liver Metastases and Concurrent Extrahepatic Disease

2017 ◽  
Vol 225 (4) ◽  
pp. e126-e127
Author(s):  
Georgios Antonios Margonis ◽  
Neda Amini ◽  
Nikolaos Andreatos ◽  
Amar Deshwar ◽  
Neda Rezaee ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease ◽  
Prognostic Relevance ◽  
Mutational Status

Results of R0 Resection for Colorectal Liver Metastases Associated With Extrahepatic Disease

2004 ◽  
Vol 11 (3) ◽  
pp. 274-280 ◽  
Author(s):  
Dominique Elias ◽  
Lucas Sideris ◽  
Marc Pocard ◽  
Jean-Francois Ouellet ◽  
Val�rie Boige ◽  
...  
Keyword(s):  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease ◽  
R0 Resection

scholarly journals Colorectal liver metastases and concomitant extrahepatic disease: is resection justified? Single center survival analysis on 84 patients

HPB ◽  
2019 ◽  
Vol 21 ◽  
pp. S581
Author(s):  
E. Panettieri ◽  
F. Ardito ◽  
A. De Rose ◽  
A. Coppola ◽  
M. Vellone ◽  
...  
Keyword(s):  
Survival Analysis ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease ◽  
Single Center

scholarly journals Liver resection is beneficial for patients with colorectal liver metastases and extrahepatic disease

2020 ◽  
Vol 8 (4) ◽  
pp. 109-109
Author(s):  
Kristina Hasselgren ◽  
Bengt Isaksson ◽  
Bjarne Ardnor ◽  
Gert Lindell ◽  
Magnus Rizell ◽  
...  
Keyword(s):  
Liver Resection ◽  
Liver Metastases ◽  
Colorectal Liver Metastases ◽  
Extrahepatic Disease
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