Comparison of Heart Rate Variability Parameters to the Autonomic Reflex Screen in Postural Orthostatic Tachycardia Syndrome and Neurogenic Orthostatic Hypotension

Significant initial orthostatic hypotension (IOH) occurs in ~50% of postural tachycardia syndrome (POTS) patients and 13% of controls. Heart rate and blood pressure recovery are prolonged in IOH sustaining lightheadedness; IOH is more prevalent and severe in POTS. Altered cerebral blood flow and cardiorespiratory regulation are more prevalent in POTS. Altered heart rate variability and baroreflex gain may cause nearly instantaneous lightheadedness in POTS. IOH alone fails to confer a strong probability of POTS.

Download Full-text

Spectral analysis of blood pressure and heart rate, catecholamine and neuropeptide Y plasma levels in a new model of neurogenic orthostatic hypotension in dog

Clinical Autonomic Research ◽

10.1007/bf02291227 ◽

1996 ◽

Vol 6 (2) ◽

pp. 75-82 ◽

Cited By ~ 10

Author(s):

P. Verwaerde ◽

J. -M. Senard ◽

M. Mazerolles ◽

M. -A. Tran ◽

C. Damase-Michel ◽

...

Keyword(s):

Blood Pressure ◽

Heart Rate ◽

Spectral Analysis ◽

Orthostatic Hypotension ◽

Neuropeptide Y ◽

Plasma Levels ◽

Neurogenic Orthostatic Hypotension ◽

New Model

Download Full-text

Analysis of Heart Rate Variability During Head-Up Tilt Testing in a Patient With Idiopathic Postural Orthostatic Tachycardia Syndrome (POTS)

Japanese Circulation Journal ◽

10.1253/jcj.63.496 ◽

1999 ◽

Vol 63 (6) ◽

pp. 496-498 ◽

Cited By ~ 3

Author(s):

Masataka Sumiyoshi ◽

Yasuro Nakata ◽

Yoriaki Mineda ◽

Masayuki Yasuda ◽

Yuji Nakazato ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Postural Orthostatic Tachycardia Syndrome ◽

Tilt Testing ◽

Head Up Tilt

Download Full-text

Hemodynamic profile and heart rate variability in hyperadrenergic versus non-hyperadrenergic postural orthostatic tachycardia syndrome

Clinical Neurophysiology ◽

10.1016/j.clinph.2015.08.015 ◽

2016 ◽

Vol 127 (2) ◽

pp. 1639-1644 ◽

Cited By ~ 3

Author(s):

Luka Crnošija ◽

Magdalena Krbot Skorić ◽

Ivan Adamec ◽

Mila Lovrić ◽

Anamari Junaković ◽

...

Keyword(s):

Heart Rate ◽

Heart Rate Variability ◽

Postural Orthostatic Tachycardia Syndrome ◽

Hemodynamic Profile

Download Full-text

Cardiac denervation occurs independent of orthostatic hypotension and impaired heart rate variability in Parkinson's disease

Aktuelle Neurologie ◽

10.1055/s-0028-1086777 ◽

2008 ◽

Vol 35 (S 01) ◽

Author(s):

C.A Haensch ◽

H Lerch ◽

J Jörg ◽

S Isenmann

Keyword(s):

Parkinson’S Disease ◽

Heart Rate ◽

Parkinson's Disease ◽

Heart Rate Variability ◽

Orthostatic Hypotension ◽

Cardiac Denervation

Download Full-text

Symbolic dynamics of heart rate variability in Parkinson's disease patients with orthostatic hypotension

International Journal of Cardiology ◽

10.1016/j.ijcard.2016.09.091 ◽

2016 ◽

Vol 225 ◽

pp. 144-146 ◽

Cited By ~ 3

Author(s):

Lauro C. Vianna ◽

André L. Teixeira ◽

Tácio S. Santos ◽

Gabriel D. Rodrigues ◽

Lidia A. Bezerra ◽

...

Keyword(s):

Parkinson’S Disease ◽

Heart Rate ◽

Parkinson's Disease ◽

Heart Rate Variability ◽

Orthostatic Hypotension ◽

Symbolic Dynamics

Download Full-text

Utility of autonomic testing for the efficient diagnosis and effective pharmacological management of neurogenic orthostatic hypotension

BMJ Case Reports ◽

10.1136/bcr-2018-228423 ◽

2019 ◽

Vol 12 (8) ◽

pp. e228423

Author(s):

Sami bin Alam ◽

Waiel Almardini ◽

Amer Suleman

Keyword(s):

Heart Rate ◽

Orthostatic Hypotension ◽

Symptomatic Relief ◽

Neurogenic Orthostatic Hypotension ◽

Pharmacological Management ◽

Autonomic Testing ◽

History Of ◽

Head Up Tilt ◽

Deep Breathing Test

A 62-year-old man presented with a 2-year history of syncope, collapse and fluctuating blood pressure (BP). His medications included midodrine (10 mg, three times per day) and fludrocortisone (0.1 mg, two times per day), but neither treatment afforded symptomatic relief. Autonomic testing was performed. Head-up tilt table testing revealed a supine BP of 112/68 mm Hg (heart rate, 74 beats per minute (bpm)) after 6 min, which dropped to 76/60 mm Hg (83 bpm) within 2 min of 80° head-up tilt. Findings from a heart rate with deep breathing test and a Valsalva test were consistent with autonomic dysfunction. The patient was diagnosed with neurogenic orthostatic hypotension and treated with droxidopa (100 mg, two times per day; titrated to 100 mg, one time per day). After initiating treatment with droxidopa, the patient no longer reported losing consciousness on standing and experienced improvement in activities of daily living. These improvements were maintained through 1 year of follow-up.

Download Full-text