The degeneration of upper and lower motor neuron from the perspective of clinical neurological examination and MRI-electromyography manifold detection in amyotrophic lateral sclerosis

Neuroreport ◽  
2020 ◽  
Vol 32 (1) ◽  
pp. 23-28
Author(s):  
Jiaoting Jin ◽  
Fangfang Hu ◽  
Qiuli Zhang ◽  
Qiaoyi Chen ◽  
Haining Li ◽  
...  
2010 ◽  
Vol 121 ◽  
pp. S145
Author(s):  
F. Baumann ◽  
R.D. Henderson ◽  
S.E. Rose ◽  
A. Pettitt ◽  
K. Pannek ◽  
...  

Neurogenetics ◽  
2012 ◽  
pp. 136-147
Author(s):  
Christopher E. Shaw ◽  
Jemeen Sreedharan ◽  
Caroline A. Vance ◽  
Ammar Al-Chalabi ◽  
Nicholas Wood

2014 ◽  
Vol 6 (3) ◽  
Author(s):  
Marco Antonio Araujo Leite ◽  
Marco Orsini ◽  
Marcos R.G. De Freitas ◽  
João Santos Pereira ◽  
Fábio Henrique Porto Gobbi ◽  
...  

Fasciculations are visible, fine and fast, sometimes vermicular contractions of fine muscle fibers that occur spontaneously and intermittently. The aim of this article is to discuss the main causes for fasciculations and their pathophysiology in different sites of the central/peripheral injury and in particular to disprove that the presence of this finding in the neurological examination is indicative of amyotrophic lateral sclerosis. Undoubtedly, most fasciculations have a distal origin in the motor nerve both in normal subjects and in patients with motor neuron disease. Most of them spread to other dendritic spines often producing an antidromic impulse in the main axon. The clinical and neurophysiological diagnosis must be thorough. It may often take long to record fasciculations with electroneuromyography. In other cases, temporal monitoring is necessary before the diagnosis. The treatment, which may be adequate in some cases, is not always necessary


Neurology ◽  
1994 ◽  
Vol 44 (6) ◽  
pp. 1101-1101 ◽  
Author(s):  
J.J.M. Kew ◽  
D. J. Brooks ◽  
R. E. Passingham ◽  
J. C. Rothwell ◽  
R. S.J. Frackowiak ◽  
...  

2020 ◽  
Vol 131 (1) ◽  
pp. 96-105 ◽  
Author(s):  
Emel Oguz Akarsu ◽  
Nermin Gorkem Sirin ◽  
Elif Kocasoy Orhan ◽  
Bahar Erbas ◽  
Hava Ozlem Dede ◽  
...  

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