scholarly journals Localisation of function in the lemur’s brain

The brain of the Lemur, the lowest of the ape-like animals, does not appear to have been subjected previously to a thorough examination. Page May and Elliott Smith brought a brief communication on the subject before the Cambridge Meeting of the British Association in 1904. Their experiments were apparently limited to stimulation of the cerebral cortex, and they have never published a full account of their work. Brodmann has worked out some of the histological details of the structure of the cortex cerebri, and Max Volsch has performed a stimulation experiment upon one Lemur. The work of these investigators will be referred to again in the course of this paper. Our own investigation has in the main dealt with the motor centres, and the experimental methods adopted have been the usual ones of stimulation and extirpation. In animals so low in the scale, stimulation is to be regarded as the more decisive of the two methods for the purpose of localisation. The extirpation experiments have, however, confirmed the results of stimulation, and in these experiments the course of the resulting degeneration was followed by histological examination of the brain and spinal cord. The results, moreover, agree remarkably closely with those obtained by a study of the histological structure of the various regions of the cortex cerebri.

1895 ◽  
Vol 58 (347-352) ◽  
pp. 206-214 ◽  

The object of this investigation was to trace by the so-called anatomical method the degeneration resulting from minute lesions of the motor area of the cortex cerebri through the brain and spinal cord, to locate the path of the conducting fibres in the internal capsule and elsewhere, to follow them as far as possible to their destinations, and by such control observations to check off the results obtained by previous excitation experiments.


1970 ◽  
Vol 32 (5) ◽  
pp. 553-559 ◽  
Author(s):  
J. Thomas Mortimer ◽  
C. Norman Shealy ◽  
Connie Wheeler

2002 ◽  
Vol 30 (02n03) ◽  
pp. 369-378 ◽  
Author(s):  
Ching-Liang Hsieh ◽  
Chin-Hsin Wu ◽  
Jaung-Geng Lin ◽  
Chuang-Chien Chiu ◽  
Mike Chen ◽  
...  

Our previous studies have shown that the cerebral cortex modulates the physiological mechanisms of acupuncture. However, the role of the brain stem and spinal cord in acupuncture remains unclear. The present study investigated the action of the brain stem and spinal cord in acupuncture. A total of eight healthy adult volunteers were studied. Electrical stimulation of the supraorbital nerve in the supraorbital foramen was used to evoke the blink reflex. Electrical stimulation of the posterior tibial nerve in the right popliteal fossa was used to evoke the H reflex. Electroacupuncture (EA) of 2 Hz was applied to the Zusanli acupoint in the right or left leg. The area of the R1 and R2 components of the blink reflex, and the greatest H/M ratio and H-M interval of the H reflex were measured before EA, during EA and at various post-EA periods. These data were analyzed quantitatively by a computerized electromyographic examination system. The results indicate that EA did not change the R1 and ipsilateral R2 components of the blink reflex. EA depressed the contralateral R2 component of the blink reflex 10 minutes and 40 minutes after the start of EA, but not after 5 minutes. EA applied to the Zusanli acupoint did not change the H/M ratio or the H-M interval of the H reflex. The results of this study indicate that 2 Hz EA of the Zusanli acupoint does not change the R1 component of the blink reflex, and the H/M ratio and the H-M interval of the H reflex, suggesting that 2 Hz EA does not change the monosynaptic reflex in the brain stem and spinal cord in humans. We also found that EA at 2-Hz depressed the contralateral but not the ipsilateral R2 component of the blink reflex, suggesting that longer pathways, perhaps including the cerebral cortex, may play a role in the physiological mechanisms responsible for the effectiveness of acupuncture.


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