In vitro antifungal activity of the flavonoid baicalein against Candida species

2012 ◽  
Vol 61 (12) ◽  
pp. 1704-1708 ◽  
Author(s):  
Rosana Serpa ◽  
Emanuele J. G. França ◽  
Luciana Furlaneto-Maia ◽  
Célia G. T. J. Andrade ◽  
Andréa Diniz ◽  
...  
2017 ◽  
Vol 5 (2) ◽  
pp. 66-69 ◽  
Author(s):  
Wanigasekara Daya Ratnasooriya ◽  
◽  
Sachitra Gayanthi Ratnasooriya ◽  
Chatura Dayendra Tissa Ratnasooriya ◽  
Ranga Dissanayake ◽  
...  

Mycoses ◽  
2011 ◽  
Vol 54 (6) ◽  
pp. e737-e743 ◽  
Author(s):  
László Galgóczy ◽  
Andrea Bácsi ◽  
Mónika Homa ◽  
Máté Virágh ◽  
Tamás Papp ◽  
...  

2019 ◽  
Vol In Press (In Press) ◽  
Author(s):  
Gonca Erkose Genc ◽  
Ozcan Sahinkaya ◽  
Candan Demir ◽  
Ozgul Kisa ◽  
Dilek Satana

2015 ◽  
Vol 31 (11) ◽  
pp. 1801-1809 ◽  
Author(s):  
Jhon J. Artunduaga Bonilla ◽  
Daissy J. Paredes Guerrero ◽  
Clara I. Sánchez Suárez ◽  
Claudia C. Ortiz López ◽  
Rodrigo G. Torres Sáez

2021 ◽  
Vol 14 (4) ◽  
Author(s):  
Gholamreza Shokoohi ◽  
Reza Rouhi ◽  
Mohammad Etehadnezhad ◽  
Bahram Ahmadi ◽  
Javad Javidnia ◽  
...  

Background: Aspergillus and Candida species are the most commonly identified fungal pathogens in otomycosis. However, we usually encounter some difficulties in its treatment because many patients show resistance to antifungal agents and present a high recurrence rate. Objectives: The current research was conducted to compare the in vitro activities of luliconazole (LUL), and efinaconazole (EFN) and the nine comparators on Aspergillus and Candida strains isolated from otomycosis. Methods: The in vitro activities of nine common antifungal drugs (amphotericin B (AMB), voriconazole (VRC), fluconazole (FLU), itraconazole (ITC), ketoconazole (KTO), clotrimazole (CLO), nystatin (NYS), terbinafine (TRB), and caspofungin (CAS)) and two novel new azoles (LUL and EFN) against of 108 clinical isolates of Aspergillus and Candida species obtained from otomycosis were assessed according to the CLSI broth microdilution document. Results: The LUL and EFN had the geometric mean minimum inhibitory concentrations (GM MICs) of 0.098 and 0.109 μg/mL against all Aspergillus strains, respectively. Furthermore, the GM MICs of all Candida isolates for LUL, EFN, CAS, CLO, VRC, AMB, ITC, KTO, FLU, NYS, and TRB were calculated to be 0.133, 0.144, 0.194, 0.219, 0.475, 0.537, 0.655, 1.277, 4.905, 9.372, and 13.592 μg/mL, respectively. Additionally, 6 (35.29%), 2 (11.7%), and 1 (5.88%) Candida isolates were resistant to FLU, CAS, and VRC, respectively. Conclusions: As the findings indicated, LUL and EFN showed the lowest GM MIC values against the examined species. Accordingly, these novel imidazole and triazole antifungal agents can be regarded as proper candidates for the treatment of otomycosis caused by Aspergillus and Candida strains.


2017 ◽  
Vol 89 (3 suppl) ◽  
pp. 2423-2432 ◽  
Author(s):  
FERNANDO A. DE OLIVEIRA ◽  
VANESSA C. RORATO ◽  
ADRIANA A. ALMEIDA-APOLONIO ◽  
ALLAN B. RODRIGUES ◽  
ALINE L. DE BARROS ◽  
...  

Author(s):  
Shahindokht Bassiri-Jahromi ◽  
Farzad Katiraee ◽  
Mannan Hajimahmoodi ◽  
Ehsan Mostafavi ◽  
Malihe Talebi. ◽  
...  

2014 ◽  
Vol 55 (4) ◽  
pp. J157-J163 ◽  
Author(s):  
Hideyo Yamaguchi ◽  
Fumiaki Ikeda ◽  
Takako Iyoda ◽  
Makoto Suzuki ◽  
Takashi Mikawa

Author(s):  
A. Silva-Dias ◽  
I. M. Miranda ◽  
J. Branco ◽  
L. Cobrado ◽  
M. Monteiro-Soares ◽  
...  

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