scholarly journals CUT&RUNTools: a flexible pipeline for CUT&RUN processing and footprint analysis

2019 ◽  
Author(s):  
Qian Zhu ◽  
Nan Liu ◽  
Stuart H. Orkin ◽  
Guo-Cheng Yuan

AbstractWe introduce CUT&RUNTools as a flexible, general pipeline for facilitating the identification of chromatin-associated protein binding and genomic footprinting analysis from antibody-targeted CUT&RUN primary cleavage data. CUT&RUNTools extracts endonuclease cut site information from sequences of short read fragments and produces single-locus binding estimates, aggregate motif footprints, and informative visualizations to support the high-resolution mapping capability of CUT&RUN. CUT&RUNTools is available at https://bitbucket.org/qzhudfci/cutruntools/.


2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Qian Zhu ◽  
Nan Liu ◽  
Stuart H. Orkin ◽  
Guo-Cheng Yuan

Abstract We introduce CUT&RUNTools as a flexible, general pipeline for facilitating the identification of chromatin-associated protein binding and genomic footprinting analysis from antibody-targeted CUT&RUN primary cleavage data. CUT&RUNTools extracts endonuclease cut site information from sequences of short-read fragments and produces single-locus binding estimates, aggregate motif footprints, and informative visualizations to support the high-resolution mapping capability of CUT&RUN. CUT&RUNTools is available at https://bitbucket.org/qzhudfci/cutruntools/.





2018 ◽  
Author(s):  
Paul M. Schenk ◽  
◽  
Britney E. Schmidt ◽  
Hanna G. Sizemore ◽  
Carle M. Pieters ◽  
...  


2019 ◽  
Vol 5 (7) ◽  
pp. 351-353 ◽  
Author(s):  
Kathryn Lauren Hong ◽  
Damien Redfearn ◽  
Sanoj Chacko ◽  
Jason Baley ◽  
Adrian Baranchuk ◽  
...  


2019 ◽  
Vol 112 ◽  
pp. 36-49 ◽  
Author(s):  
D. Nyolei ◽  
M. Nsaali ◽  
V. Minaya ◽  
A. van Griensven ◽  
B. Mbilinyi ◽  
...  


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