Mediation and graph data models for medical data integration

The Operational Data Model (ODM) is a data standard for interchanging clinical trial data. ODM contains the metadata definition of a study, i.e., case report forms, as well as the clinical data, i.e., the answers of the participants. The portal of medical data models is an infrastructure for creation, exchange, and analysis of medical metadata models. There, over 23000 metadata definitions can be downloaded in ODM format. Due to data protection law and privacy issues, clinical data is not contained in these files. Access to exemplary clinical test data in the desired metadata definition is necessary in order to evaluate systems claiming to support ODM or to evaluate if a planned statistical analysis can be performed with the defined data types. In this work, we present a web application, which generates syntactically correct clinical data in ODM format based on an uploaded ODM metadata definition. Data types and range constraints are taken into account. Data for up to one million participants can be generated in a reasonable amount of time. Thus, in combination with the portal of medical data models, a large number of ODM files including metadata definition and clinical data can be provided for testing of any ODM supporting system. The current version of the application can be tested at https://cdgen.uni-muenster.de and source code is available, under MIT license, at https://imigitlab.uni-muenster.de/published/odm-clinical-data-generator.

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Graph Data Models

Encyclopedia of Big Data Technologies ◽

10.1007/978-3-319-63962-8_81-1 ◽

2018 ◽

pp. 1-6

Author(s):

Claudio Gutierrez ◽

Jan Hidders ◽

Peter T. Wood

Keyword(s):

Data Models ◽

Graph Data

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XML-Based Toolkits for the Interoperability of Web Information Systems

Web-Enabled Systems Integration ◽

10.4018/978-1-59140-041-7.ch005 ◽

2011 ◽

pp. 91-110

Author(s):

Christophe Nicolle ◽

Kokou Yetongnon

Keyword(s):

Information Systems ◽

Data Integration ◽

Web Sites ◽

Data Models ◽

Data Sources ◽

On Demand ◽

Web Information ◽

Meta Level ◽

Web Information Systems ◽

Translation Scheme

This chapter presents a methodology and tools framework, called X-TIME, to support data integration via web sites. It is a data model translator toolkit based on a metamodel and XML technology that is aimed at facilitating the design of wrappers, semantic reconciliators or mediators. X-TIME is an adaptable semantics-oriented metamodel approach that takes into account important characteristics of interoperable information systems, including extensibility and composability. Extensibility requires a translation scheme that can easily integrate new data models while composability, which is the ability of an application to define dynamically the subset of data sources it needs, requires on-demand translation among a subset of data models. To meet these requirements, X-TIME is based on an extensible metamodel that defines a set of metatypes for representing meta-level semantic descriptors of data models that can be found in web sites. The metatypes are organized in a generalization hierarchy to capture semantic similarities between modeling concepts and correlate constituent data models of interoperable systems.

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