Traditional studies suggest oil & gas resources clusters lack effective demand for innovation and resource endowments play the most important role in their development. In this paper, we analyzed the correlation of regional innovation networks and oil & gas resources clusters. Based on identification of oil & gas resources clusters in China by calculating location entropy, we did an empirical analysis on the correlation by using related panel data. It shows that resource-based clusters demand for innovation doesnt diminish at all. With oil and gas resources deep exploration, the demand for technology innovation increases, thus forming a strong and active regional innovation networks. In turn, effective regional innovation networks contribute to these clusters sustainable development.