Addition of forelimb training reduces gains from robotic gait training in a rat model of spinal cord injury

2017 ◽  
Author(s):  
Nathan D. Neckel ◽  
Haining Dai ◽  
Olga C. Rodriguez
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Rat Model ◽  
Gait Training ◽  
Cord Injury ◽  
Robotic Gait

Skilled Reach Training Enhances Robotic Gait Training To Restore Overground Locomotion Following Spinal Cord Injury In Rats

2021 ◽  
pp. 113490
Author(s):  
Nathan D. Neckel ◽  
Haining Dai ◽  
John Hanckel ◽  
Yichien Lee ◽  
Christopher Albanese ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Gait Training ◽  
Cord Injury ◽  
Robotic Gait

scholarly journals 8B12 Effect of robotic gait training on gait pattern in patients with incomplete spinal cord injury

2012 ◽  
Vol 2012.24 (0) ◽  
pp. _8B12-1_-_8B12-2_
Author(s):  
Tomohiro TAKAHASHI ◽  
Tetuya OGAWA ◽  
Noritaka KAWASHIMA ◽  
Shin-ichiro YAMAMOTO ◽  
Toru OGATA
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Gait Training ◽  
Gait Pattern ◽  
Incomplete Spinal Cord Injury ◽  
Cord Injury ◽  
Robotic Gait

scholarly journals Effect of robotic gait training on cardiorespiratory system in incomplete spinal cord injury

2013 ◽  
Vol 50 (10) ◽  
pp. 1411-1422 ◽  
Author(s):  
Femke Hoekstra ◽  
Michiel P. M. van Nunen ◽  
Karin H. L. Gerrits ◽  
Janneke M. Stolwijk-Swüste ◽  
Martine H. P. Crins ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Gait Training ◽  
Incomplete Spinal Cord Injury ◽  
Cardiorespiratory System ◽  
Cord Injury ◽  
Robotic Gait

scholarly journals Usefulness of robotic gait training plus neuromodulation in chronic spinal cord injury: a case report

2016 ◽  
Vol 40 (1) ◽  
pp. 118-121 ◽  
Author(s):  
Rocco Salvatore Calabrò ◽  
Antonino Naro ◽  
Antonino Leo ◽  
Placido Bramanti
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Case Report ◽  
Gait Training ◽  
Chronic Spinal Cord Injury ◽  
Cord Injury ◽  
Robotic Gait

scholarly journals Multi-pronged neuromodulation intervention engages the residual motor circuitry to facilitate walking in a rat model of spinal cord injury

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Marco Bonizzato ◽  
Nicholas D. James ◽  
Galyna Pidpruzhnykova ◽  
Natalia Pavlova ◽  
Polina Shkorbatova ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Rat Model ◽  
Stress Responses ◽  
Learning Algorithm ◽  
Lumbar Spinal Cord ◽  
Cord Injury ◽  
Potential Synergy ◽  
Lumbar Spinal ◽  
Deep Brain

AbstractA spinal cord injury usually spares some components of the locomotor circuitry. Deep brain stimulation (DBS) of the midbrain locomotor region and epidural electrical stimulation of the lumbar spinal cord (EES) are being used to tap into this spared circuitry to enable locomotion in humans with spinal cord injury. While appealing, the potential synergy between DBS and EES remains unknown. Here, we report the synergistic facilitation of locomotion when DBS is combined with EES in a rat model of severe contusion spinal cord injury leading to leg paralysis. However, this synergy requires high amplitudes of DBS, which triggers forced locomotion associated with stress responses. To suppress these undesired responses, we link DBS to the intention to walk, decoded from cortical activity using a robust, rapidly calibrated unsupervised learning algorithm. This contingency amplifies the supraspinal descending command while empowering the rats into volitional walking. However, the resulting improvements may not outweigh the complex technological framework necessary to establish viable therapeutic conditions.

Sign in / Sign up

Export Citation Format

Share Document