Off-the-shelf convolutional neural network features for pulmonary nodule detection in computed tomography scans

Author(s):  
Bram van Ginneken ◽  
Arnaud A. A. Setio ◽  
Colin Jacobs ◽  
Francesco Ciompi
2021 ◽  
Vol 11 (6) ◽  
pp. 1551-1559
Author(s):  
Yudu Zhao ◽  
Jun Ma ◽  
Zhenwei Peng ◽  
Hao Xia ◽  
Honglin Wan

Early screening for pulmonary nodules is currently an important means for reducing lung cancer mortality. In recent years, three-dimensional convolutional neural networks have achieved great success in the field of pulmonary nodule detection. This paper proposes a pulmonary nodule detection method based on a threedimensional multiscale convolutional neural network with channel and spatial attention. First, a multiscale module is designed to extract the image features at different scales. Second, a channel and spatial attention module is designed to mine the correlation information between features from the perspective of space and channel. Then the extracted features are sent to a pyramid-like fusion mechanism, so that the features contain both deep semantic information and shallow position information, which is conducive to object positioning and bounding box regression. In general, the experiments on the LUng Nodule Analysis 2016 (LUNA16) dataset show that the average free-response receiver operating characteristic (FROC) score is 0.846. Compared with other current advanced methods, the method is competitive and effective.


2020 ◽  
Vol 134 (4) ◽  
pp. 328-331 ◽  
Author(s):  
P Parmar ◽  
A-R Habib ◽  
D Mendis ◽  
A Daniel ◽  
M Duvnjak ◽  
...  

AbstractObjectiveConvolutional neural networks are a subclass of deep learning or artificial intelligence that are predominantly used for image analysis and classification. This proof-of-concept study attempts to train a convolutional neural network algorithm that can reliably determine if the middle turbinate is pneumatised (concha bullosa) on coronal sinus computed tomography images.MethodConsecutive high-resolution computed tomography scans of the paranasal sinuses were retrospectively collected between January 2016 and December 2018 at a tertiary rhinology hospital in Australia. The classification layer of Inception-V3 was retrained in Python using a transfer learning method to interpret the computed tomography images. Segmentation analysis was also performed in an attempt to increase diagnostic accuracy.ResultsThe trained convolutional neural network was found to have diagnostic accuracy of 81 per cent (95 per cent confidence interval: 73.0–89.0 per cent) with an area under the curve of 0.93.ConclusionA trained convolutional neural network algorithm appears to successfully identify pneumatisation of the middle turbinate with high accuracy. Further studies can be pursued to test its ability in other clinically important anatomical variants in otolaryngology and rhinology.


2019 ◽  
Vol 134 (1) ◽  
pp. 52-55 ◽  
Author(s):  
J Huang ◽  
A-R Habib ◽  
D Mendis ◽  
J Chong ◽  
M Smith ◽  
...  

AbstractObjectiveDeep learning using convolutional neural networks represents a form of artificial intelligence where computers recognise patterns and make predictions based upon provided datasets. This study aimed to determine if a convolutional neural network could be trained to differentiate the location of the anterior ethmoidal artery as either adhered to the skull base or within a bone ‘mesentery’ on sinus computed tomography scans.MethodsCoronal sinus computed tomography scans were reviewed by two otolaryngology residents for anterior ethmoidal artery location and used as data for the Google Inception-V3 convolutional neural network base. The classification layer of Inception-V3 was retrained in Python (programming language software) using a transfer learning method to interpret the computed tomography images.ResultsA total of 675 images from 388 patients were used to train the convolutional neural network. A further 197 unique images were used to test the algorithm; this yielded a total accuracy of 82.7 per cent (95 per cent confidence interval = 77.7–87.8), kappa statistic of 0.62 and area under the curve of 0.86.ConclusionConvolutional neural networks demonstrate promise in identifying clinically important structures in functional endoscopic sinus surgery, such as anterior ethmoidal artery location on pre-operative sinus computed tomography.


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