Recent work has proposed an exergy-based strategy to achieve optimal system-wide performance via localized control of individual data center thermal management components. This paper presents the results of a case study where the proposed approach is applied to a data center with two rows of computing racks and two Computer Room Air-Conditioning (CRAC) units. The formulated model is used to predict the optimal data center configuration in terms of supply temperatures, flowrates, and rack heat load configurations. Two extreme cases are chosen: one with the maximum experimental heat load in the data center, and one with a minimal experimental heat load. For each case, the optimal settings for each CRAC unit were predicted using the model and using temperature + flow measurements in the data center. The setpoints predicted by the model for optimal CRAC flow and supply temperature were within 25% of the experimentally determined optima.