Characterization of Herpes Simplex Virus type 1 thymidine kinase mutants engineered for improved ganciclovir or acyclovir activity

Protein Science ◽

10.1110/ps.2460102 ◽

2009 ◽

Vol 11 (9) ◽

pp. 2267-2272 ◽

Author(s):

Mark S. Kokoris ◽

Margaret E. Black

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

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Characterization of Multiple Nuclear Localization Signals in Herpes Simplex Virus Type 1 Thymidine Kinase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1999.1485 ◽

1999 ◽

Vol 264 (2) ◽

pp. 338-342 ◽

Author(s):

Bart Degrève ◽

Robert Esnouf ◽

Erik De Clercq ◽

Jan Balzarini

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Nuclear Localization ◽

Herpes Simplex Virus Type ◽

Nuclear Localization Signals ◽

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Characterization of Eukaryotic Transcriptional Control Signals by Assay of Herpes Simplex Virus Type 1 Thymidine Kinase

Journal of General Virology ◽

10.1099/0022-1317-64-12-2679 ◽

1983 ◽

Vol 64 (12) ◽

pp. 2679-2696 ◽

Author(s):

J. C. Lang ◽

N. M. Wilkie ◽

D. A. Spandidos

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Transcriptional Control ◽

Control Signals ◽

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Biochemical and Structural Characterization of (South)-Methanocarbathymidine That Specifically Inhibits Growth of Herpes Simplex Virus Type 1 Thymidine Kinase-transduced Osteosarcoma Cells

Journal of Biological Chemistry ◽

10.1074/jbc.m313343200 ◽

2004 ◽

Vol 279 (31) ◽

pp. 32832-32838 ◽

Author(s):

Pierre Schelling ◽

Michael T. Claus ◽

Regula Johner ◽

Victor E. Marquez ◽

Georg E. Schulz ◽

...

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Structural Characterization ◽

Herpes Simplex Virus Type ◽

Osteosarcoma Cells ◽

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Genotypic and phenotypic characterization of the thymidine kinase of ACV-resistant HSV-1 derived from an acyclovir-sensitive herpes simplex virus type 1 strain1

Antiviral Research ◽

10.1016/s0166-3542(02)00131-6 ◽

2002 ◽

Vol 56 (3) ◽

pp. 253-262 ◽

Author(s):

M SAIJO ◽

T SUZUTANI ◽

E DECLERCQ ◽

M NIIKURA ◽

A MAEDA ◽

...

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Phenotypic Characterization ◽

Simplex Virus ◽

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Characterization of pyrimidine deoxyribonucleoside kinase (thymidine kinase) and thymidylate kinase as a multifunctional enzyme in cells transformed by herpes simplex virus type 1 and in cells infected with mutant strains of herpes simplex virus.

Journal of Virology ◽

10.1128/jvi.30.3.942-945.1979 ◽

1979 ◽

Vol 30 (3) ◽

pp. 942-945 ◽

Author(s):

M S Chen ◽

W P Summers ◽

J Walker ◽

W C Summers ◽

W H Prusoff

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Thymidine Kinase ◽

Herpes Simplex Virus Type ◽

Mutant Strains ◽

Simplex Virus ◽

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Detailed Characterization of an Apparently Unspliced Herpes Simplex Virus Type 1 Gene Mapping in the Interior of Another

Journal of Virology ◽

10.1128/jvi.45.2.899-899.1983 ◽

1983 ◽

Vol 45 (2) ◽

pp. 899-899 ◽

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Gene Mapping ◽

Herpes Simplex Virus Type ◽

Detailed Characterization ◽

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Purification and characterization of UL9, the herpes simplex virus type 1 origin-binding protein.

Journal of Virology ◽

10.1128/jvi.66.7.3986-3995.1992 ◽

1992 ◽

Vol 66 (7) ◽

pp. 3986-3995 ◽

Author(s):

D S Fierer ◽

M D Challberg

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Herpes Simplex Virus Type ◽

Binding Protein ◽

Purification And Characterization ◽

Origin Binding Protein ◽

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Expression, Purification, and Functional Characterization of the DNA-Binding Domain of the Herpes Simplex Virus Type 1 UL9 Protein

Protein Expression and Purification ◽

10.1006/prep.1993.1005 ◽

1993 ◽

Vol 4 (1) ◽

pp. 32-37 ◽

Author(s):

R. Martinez ◽

C.A. Edwards

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Dna Binding ◽

Herpes Simplex Virus Type ◽

Functional Characterization ◽

Dna Binding Domain ◽

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Further characterization of ts1–8, a mutant of herpes simplex virus type 1

Virus Research ◽

10.1016/0168-1702(91)90062-z ◽

1991 ◽

Vol 20 (1) ◽

pp. 71-83

Author(s):

Edward F. Arko ◽

Jasmine I. Daksis ◽

Voon-Loong Chan

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Herpes Simplex Virus Type ◽

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Generation and Characterization of UL21-Null Herpes Simplex Virus Type 1

Frontiers in Microbiology ◽

10.3389/fmicb.2012.00394 ◽

2012 ◽

Vol 3 ◽

Author(s):

Yoshifumi Muto ◽

Fumi Goshima ◽

Yoko Ushijima ◽

Hiroshi Kimura ◽

Yukihiro Nishiyama

Keyword(s):

Herpes Simplex Virus ◽

Herpes Simplex ◽

Herpes Simplex Virus Type ◽

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