Expression and Role of Integrin Receptors in Sézary Syndrome

1992 ◽  
Vol 99 (2) ◽  
pp. 151-159 ◽  
Author(s):  
Paola Savoia ◽  
Mauro Novelli ◽  
Maria Teresa Fierro ◽  
Ottavio Cremona ◽  
Pier Carlo Marchisio ◽  
...  
Keyword(s):  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Integrin Receptors

scholarly journals The Role of Tumor Microenvironment in the Pathogenesis of Sézary Syndrome

2022 ◽  
Vol 23 (2) ◽  
pp. 936
Author(s):  
Denis Miyashiro ◽  
Bruno de Castro e Souza ◽  
Marina Passos Torrealba ◽  
Kelly Cristina Gomes Manfrere ◽  
Maria Notomi Sato ◽  
...  
Keyword(s):  
Tumor Microenvironment ◽  
Immune Dysregulation ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Immunologic Response ◽  
T Cell Lymphomas ◽  
Sézary Cells ◽  
Peripheral Blood Involvement ◽  
Malignant T Cells

Sézary syndrome is an aggressive leukemic variant of cutaneous T-cell lymphomas, characterized by erythroderma, lymphadenopathy, and peripheral blood involvement by CD4+ malignant T-cells. The pathogenesis of Sézary syndrome is not fully understood. However, the course of the disease is strongly influenced by the tumor microenvironment, which is altered by a combination of cytokines, chemokines, and growth factors. The crosstalk between malignant and reactive cells affects the immunologic response against tumor cells causing immune dysregulation. This review focuses on the interaction of malignant Sézary cells and the tumor microenvironment.

scholarly journals The current management of mycosis fungoides and Sézary syndrome and the role of radiotherapy: Principles and indications

2014 ◽  
Vol 19 (2) ◽  
pp. 77-91 ◽  
Author(s):  
Ercole Mazzeo ◽  
Laura Rubino ◽  
Michela Buglione ◽  
Paolo Antognoni ◽  
Stefano Maria Magrini ◽  
...  
Keyword(s):  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Current Management

scholarly journals The role of 9-O-acetylated ganglioside D3 (CD60) and  4 1 (CD49d) expression in predicting the survival of patients with Sezary syndrome

Haematologica ◽  
2010 ◽  
Vol 95 (11) ◽  
pp. 1905-1912 ◽  
Author(s):  
E. Scala ◽  
D. Abeni ◽  
D. Pomponi ◽  
M. G. Narducci ◽  
G. A. Lombardo ◽  
...  
Keyword(s):  
Sézary Syndrome ◽  
Sezary Syndrome

The role of versican on the pathogenesis of Sèzary syndrome

2016 ◽  
Vol 84 (1) ◽  
pp. e19-e20
Author(s):  
Kazuyasu Fujii ◽  
Maria Karpova ◽  
Phil Cheng ◽  
Takuro Kanekura ◽  
Keiji Iwatsuki ◽  
...  
Keyword(s):  
Sézary Syndrome ◽  
Sezary Syndrome

Abstract 761: The role of PI3 kinase pathway in the the skin of Sezary syndrome

2018 ◽  
Author(s):  
Cristina Cristofoletti ◽  
Antonella Bresin ◽  
Mario Picozza ◽  
Maria Cristina Picchio ◽  
Francesca Passarelli ◽  
...  
Keyword(s):  
Pi3 Kinase ◽  
Sézary Syndrome ◽  
Sezary Syndrome ◽  
Pi3 Kinase Pathway ◽  
Kinase Pathway

scholarly journals The Role of Tumor Microenvironment in Mycosis Fungoides and Sézary Syndrome

2021 ◽  
Vol 33 (6) ◽  
pp. 487
Author(s):  
Zhaorui Liu ◽  
Xuesong Wu ◽  
Sam T. Hwang ◽  
Jie Liu
Keyword(s):  
Tumor Microenvironment ◽  
Mycosis Fungoides ◽  
Sézary Syndrome ◽  
Sezary Syndrome
Sign in / Sign up

Export Citation Format

Share Document