Associations between metformin use and vitamin B 12 levels, anemia, and neuropathy in patients with diabetes: a meta‐analysis

2019 ◽  
Vol 11 (9) ◽  
pp. 729-743 ◽  
Author(s):  
Wenjia Yang ◽  
Xiaoling Cai ◽  
Haiya Wu ◽  
Linong Ji
Keyword(s):  
Meta Analysis ◽  
Vitamin B ◽  
Patients With Diabetes ◽  
Vitamin B 12

scholarly journals Dietary Intake of Homocysteine Metabolism-Related B-Vitamins and the Risk of Stroke: A Dose-Response Meta-Analysis of Prospective Studies

2020 ◽  
Author(s):  
Liyun Chen ◽  
Qianwen Li ◽  
Xuexian Fang ◽  
Xinhui Wang ◽  
Junxia Min ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Dose Response ◽  
Prospective Studies ◽  
Meta Analysis ◽  
B Vitamins ◽  
Dietary Vitamin ◽  
Vitamin B ◽  
Inverse Association ◽  
Vitamin B 12 ◽  
Reduced Risk

ABSTRACT Observational studies regarding the putative associations between dietary intake of homocysteine metabolism-related B-vitamins (vitamin B-6, folate, and vitamin B-12) and stroke risk have yielded inconsistent results. Thus, we conducted a systematic meta-analysis of prospective studies in order to examine the relation between the dietary (from diet and supplements) intake of these B-vitamins and the risk of stroke. PubMed and Web of Science were searched for relevant articles published through to 25 February, 2020, and RR of stroke in relation to dietary intake of vitamin B-6, folate, and vitamin B-12 were pooled using a random-effects model. Eleven publications of 12 prospective studies comprising 389,938 participants and 10,749 cases were included in the final analysis. We found that dietary intake of vitamin B-6 and folate were associated with a reduced risk of stroke, and this inverse association remained significant in studies with >10 y of follow-up periods and among participants without a pre-existing stroke event. A dose-response analysis revealed a linear inverse association between folate and vitamin B-6 intake and the risk of stroke, with a pooled RR of 0.94 (95% CI: 0.90–0.98) and 0.94 (95% CI: 0.89–0.99) for each 100 μg/d increment in folate intake and 0.5 mg/d increment in vitamin B-6 intake, respectively. In contrast, we found no significant association between dietary vitamin B-12 intake and the risk of stroke, with an RR of 1.01 (95% CI: 0.97–1.06) per 3 μg/d increase. In conclusion, our findings suggest that increased intake of vitamin B-6 and folate is associated with a reduced risk of stroke, supporting the notion that increasing habitual folate and vitamin B-6 intake may provide a small but beneficial effect with respect to stroke.

scholarly journals Prevalence of vitamin B-12 insufficiency during pregnancy and its effect on offspring birth weight: a systematic review and meta-analysis

2016 ◽  
Vol 103 (5) ◽  
pp. 1232-1251 ◽  
Author(s):  
Nithya Sukumar ◽  
Snorri B Rafnsson ◽  
Ngianga-Bakwin Kandala ◽  
Raj Bhopal ◽  
Chittaranjan S Yajnik ◽  
...  
Keyword(s):  
Systematic Review ◽  
Birth Weight ◽  
Meta Analysis ◽  
Vitamin B ◽  
Vitamin B 12

A randomized controlled trial on the effects of adding vitamin B 12 and folate

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
N Haiden ◽  
K Klebermass ◽  
F Cardona ◽  
J Schwindt ◽  
A Berger ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Vitamin B ◽  
Randomized Controlled ◽  
Vitamin B 12

A randomized controlled trial on the effects of adding vitamin B 12 and folate

2006 ◽  
Vol 210 (S 5) ◽  
Author(s):  
N Haiden ◽  
K Klebermass ◽  
F Cardona ◽  
J Schwindt ◽  
A Berger ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Vitamin B ◽  
Randomized Controlled ◽  
Vitamin B 12

Effects of wearable technology on patients with diabetes: A systematic review and meta-analysis (Preprint)

2020 ◽  
Author(s):  
Dongjun Wu ◽  
Nicholas Buys ◽  
Guandong Xu ◽  
Jing Sun
Keyword(s):  
Systematic Review ◽  
Blood Pressure ◽  
Relapse Prevention ◽  
Diabetes Management ◽  
Meta Analysis ◽  
Intervention Group ◽  
Wearable Technologies ◽  
Patients With Diabetes ◽  
Hba1c Levels

UNSTRUCTURED Aims: This systematic review and meta-analysis aimed to evaluate the effects of wearable technologies on HbA1c, blood pressure, body mass index (BMI), and fastening blood glucose (FBG) in patients with diabetes. Methods: We searched PubMed, Scopus, Embase, the Cochrane database, and the Chinese CNKI database from last 15 years until August 2021. The quality of the 16 included studies was assessed using the PEDro scale, and random effect models were used to estimate outcomes, with I2 used for heterogeneity testing. Results: A significant reduction in HbA1c (-0.475% [95% CI -0.692 to -0.257, P<0.001]) was found following telemonitoring. However, the results of the meta-analysis did not show significant changes in blood pressure, BMI, and glucose, in the intervention group (P>0.05), although the effect size for systolic blood pressure (0.389) and diastolic blood pressure may indicate a significant effect. Subgroup analysis revealed statistically significant effects of wearable technologies on HbA1c when supported by dietetic interventions (P<0.001), medication monitoring (P<0.001), and relapse prevention (P<0.001). Online messages and telephone interventions significantly affected HbA1c levels (P<0.001). Trials with additional online face-to-face interventions showed greater reductions in HbA1c levels. Remote interventions including dietetic advice (P<0.001), medication (P<0.001), and relapse prevention (P<0.001) during telemonitoring showed a significant effect on HbA1c, particularly in patients attending ten or more intervention sessions (P<0.001). Conclusion: Wearable technologies can improve diabetes management by simplifying self-monitoring, allowing patients to upload their live measurement results frequently and thereby improving the quality of telemedicine. Wearable technologies also facilitate remote medication management, dietetic interventions, and relapse prevention.

Sign in / Sign up

Export Citation Format

Share Document