Phenobarbital rheumatism—A fresh look at an old malady: Case report and systematic review of literature

2020 ◽  
Vol 23 (4) ◽  
pp. 589-594 ◽  
Author(s):  
Saket Jha ◽  
Amal Basnet ◽  
Rajiv Ranjan Kumar ◽  
Aadhaar Dhooria ◽  
Venkata Subramanian Krishnaraju ◽  
...  
2016 ◽  
Vol 14 (4) ◽  
pp. e435-e439 ◽  
Author(s):  
Wei Keith Tan ◽  
Mae-Yen Tan ◽  
Wei Shen Tan ◽  
Soon Ching Gan ◽  
Rajadurai Pathmanathan ◽  
...  

2021 ◽  
Vol 14 (12) ◽  
pp. e246005
Author(s):  
Louise Gurowich ◽  
Gabriel Yiin ◽  
Adam Maxwell ◽  
Alexandra Rice

Myasthenia gravis (MG) is an autoimmune condition affecting the neuromuscular junction characterised by weakness and fatiguability, carrying a high morbidity if treatment is delayed. A clear association with thymoma has led to management with thymectomy as a common practice, but MG presenting post-thymectomy has rarely been reported. We present a case of an 82- year-old woman developing fatigue, ptosis and dysarthria 3 months after thymectomy. After a clinical diagnosis of MG was made, she responded well to prompt treatment with prednisolone and pyridostigmine. Her anti-acetylcholine receptor antibody (anti-AChR) subsequently came back positive. Our systematic review reveals that post-thymectomy MG can be categorised as early-onset or late-onset form with differing aetiology, and demonstrated correlation between preoperative anti-AChR titres and post-thymectomy MG. The postulated mechanisms for post-thymectomy MG centre around long-lasting peripheral autoantibodies. Clinicians should actively look for MG symptoms in thymoma patients and measure anti-AChR preoperatively to aid prognostication.


2019 ◽  
Vol 20 (11) ◽  
pp. 15-20 ◽  
Author(s):  
Zain Ul Abideen Asad ◽  
Sardar Hassan Ijaz ◽  
Amna Mohyud Din Chaudhary ◽  
Safi U. Khan ◽  
Aneesh Pakala

2014 ◽  
Vol 45 (S1) ◽  
pp. 129-131 ◽  
Author(s):  
N. Michot ◽  
P-E. Robert ◽  
A De Muret ◽  
F. Marques ◽  
L. de Calan ◽  
...  

2018 ◽  
Vol 42 (6) ◽  
pp. 604-609 ◽  
Author(s):  
A. Zullo ◽  
R. Manta ◽  
V. De Francesco ◽  
G. Fiorini ◽  
E. Lahner ◽  
...  

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