High Single-dose Vancomycin Loading Is Not Associated With Increased Nephrotoxicity in Emergency Department Sepsis Patients

2016 ◽  
Vol 23 (6) ◽  
pp. 744-746 ◽  
Author(s):  
Jamie M. Rosini ◽  
Joshua J. Davis ◽  
Jeffrey Muenzer ◽  
Brian J. Levine ◽  
Mia A. Papas ◽  
...  
Keyword(s):  
Emergency Department ◽  
Single Dose ◽  
High Single Dose

Effect of a single dose of i.v. ondansetron on QTc interval in emergency department patients

2018 ◽  
Vol 75 (5) ◽  
pp. 276-282 ◽  
Author(s):  
Kai Li ◽  
Kathy Vo ◽  
Byron K. Lee ◽  
Newton Addo ◽  
Zlatan Coralic
Keyword(s):  
Emergency Department ◽  
Single Dose ◽  
Qtc Interval ◽  
Emergency Department Patients

Comparison of Oral Ibuprofen at Three Single-Dose Regimens for Treating Acute Pain in the Emergency Department: A Randomized Controlled Trial

2019 ◽  
Vol 74 (4) ◽  
pp. 530-537 ◽  
Author(s):  
Sergey Motov ◽  
Aidin Masoudi ◽  
Jefferson Drapkin ◽  
Cecily Sotomayor ◽  
Samuel Kim ◽  
...  
Keyword(s):  
Emergency Department ◽  
Randomized Controlled Trial ◽  
Single Dose ◽  
Acute Pain ◽  
Controlled Trial ◽  
Randomized Controlled ◽  
Oral Ibuprofen

Safety and tolerability of i.v. push piperacillin/tazobactam within an emergency department

2020 ◽  
Vol 77 (13) ◽  
pp. 1051-1053
Author(s):  
William Blake Hays ◽  
Tara Flack
Keyword(s):  
Emergency Department ◽  
Single Dose ◽  
Allergic Reaction ◽  
Broad Spectrum ◽  
Chart Review ◽  
Retrospective Chart Review ◽  
Primary Objective ◽  
Drug Reactions ◽  
Broad Spectrum Antibiotic ◽  
Peripheral Site

Abstract Purpose Piperacillin/tazobactam is a broad-spectrum antibiotic that is widely used and commonly administered via the intravenous (i.v.) piggyback route over 0.5 to 4.0 hours. Recommendations for i.v. push (IVP) administration of piperacillin/tazobactam are lacking due to the high osmolality of the solution. The primary objective of this study was to retrospectively assess the safety and tolerability of piperacillin/tazobactam administered peripherally by IVP. Methods. A retrospective chart review was conducted to evaluate adverse drug reactions after administration of a single dose of IVP piperacillin/tazobactam through a peripheral line in an emergency department from August 2016 through November 2017. Results A total of 1,813 patients received 1 dose of IVP piperacillin/tazobactam during the study timeframe. Three hundred patients were randomly selected for assessment of safety and tolerability. Two hundred ninety-nine patients (99.7%) tolerated IVP piperacillin/tazobactam. One patient had an allergic reaction that included itching and hives. No infusion-related reactions were documented. Conclusion IVP administration of piperacillin/tazobactam through a peripheral site is safe and tolerable for adult patients.

scholarly journals Re-Treatment of Recurrent Bulky Lesions with High Single Dose Partial Irradiation Targeting the Hypoxic Tumor Segment (PITH): A Case Series

2019 ◽  
Vol 105 (1) ◽  
pp. E578 ◽  
Author(s):  
M. Massaccesi ◽  
N. Dinapoli ◽  
L. Boldrini ◽  
L. Cervone ◽  
L. Placidi ◽  
...  
Keyword(s):  
Single Dose ◽  
Case Series ◽  
High Single Dose ◽  
Hypoxic Tumor

Adverse Reactions to Metoclopramide in Young Children: A 6-Year Retrospective Study and Review of the Literature

2002 ◽  
Vol 18 (3) ◽  
pp. 125-127 ◽  
Author(s):  
Matityahu Lifshitz ◽  
Vladimir Gavrilov
Keyword(s):  
Emergency Department ◽  
Single Dose ◽  
Young Children ◽  
Medical Records ◽  
Adverse Reactions ◽  
Review Of The Literature ◽  
Great Caution ◽  
Single Intravenous Injection ◽  
Patients Âgés ◽  
Oculogyric Crisis

Objective To report our experience with children admitted to the emergency department between the years 1994 and 1999 for adverse reactions to metoclopramide. Patients and Methods The medical records of 52 children admitted for adverse reactions to metoclopramide were analyzed retrospectively. All the patients had been prescribed metoclopramide for the treatment of nausea and vomiting. Results The patients' ages ranged from 1.5 to 4.5 years (median 2.4 y). All had manifested various dystonic symptoms that occurred several hours after ingestion of 1 or 2, rarely more, doses of metoclopramide. Thirty-two patients had received metoclopramide 0.1 mg/kg/dose, 11 children 0.2 mg/kg/dose, 7 pateints 0.3 mg/kg/dose; for the remaining 2 children, the dosage was not known. The prominent clinical sign in all the children was oculogyric crisis. All the patients who had received a two- to threefold overdose, as well as those infants for whom the dosage was not known, experienced drowsiness. All 52 children were treated intravenously with a single dose of procyclidine hydrochloride 0.1 mg/kg. Extrapyramidal symptoms were abolished 15–30 minutes after treatment, and the children were discharged home 2–3 hours after treatment, free of symptoms. Conclusions Young children are especially susceptible to adverse reactions from metoclopramide, particularly oculogyric crisis. Therefore, physicians should use this drug with great caution. Our study indicates that it is fairly safe to treat oculogyric crisis in children with a single intravenous injection of procyclidine hydrochloride 0.1 mg/kg.

High single-dose alternate-day corticosteroid regimens in treatment of polymyositis

1985 ◽  
Vol 232 (3) ◽  
pp. 175-178 ◽  
Author(s):  
Makoto Uchino ◽  
Shukuro Araki ◽  
Osamu Yoshida ◽  
Kazutoshi Uekawa ◽  
Jinro Nagata
Keyword(s):  
Single Dose ◽  
High Single Dose

High Single Dose of Mitoxantrone and Cytarabine in Acute Non-Lymphocytic Leukemia: A Pharmacokinetic and Clinical Study

1998 ◽  
Vol 20 (6) ◽  
pp. 640-645 ◽  
Author(s):  
Lars Möllgård ◽  
Ulf Tidefelt ◽  
Britt Sundman-Engberg ◽  
Christina Löfgren ◽  
Sören Lehman ◽  
...  
Keyword(s):  
Single Dose ◽  
Clinical Study ◽  
Lymphocytic Leukemia ◽  
High Single Dose

Stereotactic, high single-dose irradiation of stage I non-small cell lung cancer (NSCLC) using four-dimensional CT scans for treatment planning

Lung Cancer ◽  
2008 ◽  
Vol 60 (2) ◽  
pp. 193-199 ◽  
Author(s):  
Peter Fritz ◽  
Hans-Jörg Kraus ◽  
Thomas Blaschke ◽  
Werner Mühlnickel ◽  
Konstantin Strauch ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Single Dose ◽  
Small Cell Lung Cancer ◽  
Treatment Planning ◽  
Cell Lung Cancer ◽  
Small Cell ◽  
Ct Scans ◽  
Small Cell Lung ◽  
Dose Irradiation ◽  
High Single Dose
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