scholarly journals Male‐female ratios in autism spectrum disorders by age, intellectual disability and attention deficit/hyperactivity disorder

2021 ◽  
Author(s):  
Maj‐Britt Posserud ◽  
Berit Skretting Solberg ◽  
Anders Engeland ◽  
Jan Haavik ◽  
Kari Klungsøyr
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Attention Deficit ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders

scholarly journals Association of maternal diabetes with neurodevelopmental disorders: autism spectrum disorders, attention-deficit/hyperactivity disorder and intellectual disability

2020 ◽  
Author(s):  
Shuyun Chen ◽  
Sixian Zhao ◽  
Christina Dalman ◽  
Håkan Karlsson ◽  
Renee Gardner
Keyword(s):  
Diabetes Mellitus ◽  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Intellectual Disability ◽  
Attention Deficit ◽  
Neurodevelopmental Disorders ◽  
Maternal Diabetes ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders

Abstract Background Maternal diabetes has been associated with a risk of neurodevelopmental disorders (NDDs) in offspring, though the common co-occurrence of autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) and intellectual disability (ID) is rarely considered, nor is the potential for confounding by shared familial factors (e.g. genetics). Methods This population-based cohort study used data from Psychiatry Sweden, a linkage of Swedish national registers, to follow 2 369 680 individuals born from 1987 to 2010. We used population-averaged logit models to examine the association between exposure to maternal type 1 diabetes mellitus (T1DM), pre-gestational type 2 diabetes mellitus (T2DM) or gestational diabetes mellitus (GDM), and odds of NDDs in offspring. Subgroup analysis was then performed to investigate the timings of GDM diagnosis during pregnancy and its effect on the odds of NDDs in offspring. We compared these results to models considering paternal lifetime T1DM and T2DM as exposures. Results Overall, 45 678 individuals (1.93%) were diagnosed with ASD, 20 823 (0.88%) with ID and 102 018 (4.31%) with ADHD. All types of maternal diabetes were associated with odds of NDDs, with T2DM most strongly associated with any diagnosis of ASD (odds ratioadjusted 1.37, 95% confidence interval 1.03–1.84), ID (2.09, 1.53–2.87) and ADHD (1.43, 1.16–1.77). Considering common co-morbid groups, the associations were strongest between maternal diabetes and diagnostic combinations that included ID. Paternal T1DM and T2DM diagnoses were also associated with offspring NDDs, but these associations were weaker than those with maternal diabetes. Diagnosis of GDM between 27 and 30 weeks of gestation was generally associated with the greatest risk of NDDs in offspring, with the strongest associations for outcomes that included ID. Conclusion The association of maternal diabetes with NDDs in offspring varies depending on the co-morbid presentation of the NDDs, with the greatest odds associated with outcomes that included ID. Results of paternal-comparison studies suggest that the above associations are likely to be partly confounded by shared familial factors, such as genetic liability.

scholarly journals Attention deficit/hyperactivity disorder symptoms moderate cognition and behavior in children with autism spectrum disorders

2009 ◽  
pp. n/a-n/a ◽  
Author(s):  
Benjamin E. Yerys ◽  
Gregory L. Wallace ◽  
Jennifer L. Sokoloff ◽  
Devon A. Shook ◽  
Joette D. James ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Attention Deficit ◽  
Children With Autism ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders ◽  
And Behavior

scholarly journals Socioemotional profiles of autism spectrum disorders, attention deficit hyperactivity disorder, and disinhibited and reactive attachment disorders: a symptom comparison and network approach

2021 ◽  
pp. 1-10
Author(s):  
Barry Coughlan ◽  
Matt Woolgar ◽  
Marinus H. van IJzendoorn ◽  
Robbie Duschinsky
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Attention Deficit ◽  
Autism Spectrum ◽  
Attachment Disorders ◽  
Hyperactivity Disorder ◽  
Children With Asd ◽  
Significant Difference ◽  
Reactive Attachment ◽  
Spectrum Disorders

Abstract Children with autism spectrum disorders (ASDs), attention deficit hyperactivity disorder (ADHD) and disinhibited and reactive attachment disorders (RAD/DAD) often experience socioemotional problems. Elucidating a clear picture of these profiles is essential. Strengths and Difficulties Questionnaires (SDQs) were analysed from cohort of children with ASD (n = 1430), ADHD (n = 1193), and RAD/DAD (n = 39). Kruskal–Wallis Tests and network analytic techniques were used to investigate symptom profiles. Children with ASD experienced more emotional problems, peer problems and fewer prosocial behaviours. Children with ADHD and RAD/DAD had higher levels of hyperactivity and conduct problems. Overall, ASD and ADHD networks were highly correlated (rs = 0.82), and we did not observe a statistically significant difference in terms of global Strength.

scholarly journals Human Plasma Glycome in Attention-Deficit Hyperactivity Disorder and Autism Spectrum Disorders

2010 ◽  
Vol 10 (1) ◽  
pp. M110.004200 ◽  
Author(s):  
Nela Pivac ◽  
Ana Knežević ◽  
Olga Gornik ◽  
Maja Pučić ◽  
Wilmar Igl ◽  
...  
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Human Plasma ◽  
Attention Deficit ◽  
Autism Spectrum ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders

762 Burn Mechanisms in Pediatric Patients with Autism Spectrum Disorders and Attention Deficit/hyperactivity Disorder: A Multisite Retrospective Study

2020 ◽  
Vol 41 (Supplement_1) ◽  
pp. S214-S215
Author(s):  
Elena Maria S Munoz ◽  
Farzin Sadeq ◽  
Atilla Ceranoglu ◽  
Robert Sheridan
Keyword(s):  
Attention Deficit Hyperactivity Disorder ◽  
Autism Spectrum Disorders ◽  
Attention Deficit ◽  
Pediatric Patients ◽  
Burn Injury ◽  
Reference Group ◽  
Autism Spectrum ◽  
Burn Patients ◽  
Hyperactivity Disorder ◽  
Spectrum Disorders

Abstract Introduction Although autism spectrum disorders (ASD) and attention deficit/hyperactivity disorder (ADHD) have been associated with higher risk of specific types of burns, mechanisms and circumstances of injury should be investigated for prevention and education. Methods A multisite retrospective review of 841 patients treated at pediatric burns hospitals assessed a subsample of Burn Outcomes Questionnaire (BOQ) data collected from years 2001 to 2010. Demographic and clinical characteristics of burn injury were compared. The current study evaluates burn mechanisms and patients diagnosed with ASD/ADHD as indicated in the co-morbid conditions field of the BOQ through logistic regression analyses. Results Of the 841 patients who completed the BOQ, there were 227 patients with diagnoses of ASD/ADHD. Age is not statistically significant when considering burn injury due to Play, which includes match play, fire play, and similar behaviors (P=0.36). However, patients with ASD/ADHD were older than the reference group (10.2 years, 8.32 years, P< .0001) and the same pattern is observed when considering burn injury due to Self-Infliction (10.7 years, 8.04 years, P< .001), Play (10.7 years, 8.27 years, P< .01), and Self-Infliction Not Play (10.7 years, 4.40 years, P=.03). Pediatric burn patients with ASD/ADHD are 1.80 times as likely to have sustained burn injury due to Play than the reference group and have 2 times the odds (odds ratio [OR]: 2, [95% confidence interval (CI): 1.32, 3.03], P< .001). Additionally, pediatric patients with ASD/ADHD are 4.06 times as likely to have sustained burn injury due to Self-Infliction Not Play and have 4.18 times the odds (OR: 4.18, 95% CI (1.47,11.89), P< .01). Conclusions The research suggests that pediatric burn patients with ASD/ADHD are more likely to sustain burn injury through Play and other methods of Self-Infliction. Pediatric patients with ASD/ADHD are older than the reference group. Difference in age is partly due to older patients who sustained burn injury secondary to seizure. Though more research is needed for burn circumstances, these secondary injuries mostly present as contact and scald burns occurring in outdoor settings or kitchens. Patients without ASD/ADHD and burn injury due to Self-Infliction Not Play were predominantly toddler and preschool aged, and presented with scald and contact burns related to bathing and feeding. Applicability of Research to Practice Further research is needed to better understand ASD/ADHD and burns, with particular emphasis on differentiating the 2 diagnoses and burn circumstances. Patients with ASD/ADHD and caregivers may benefit from research in burn injury risk for prevention and counseling.

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