The efficacy of greater occipital nerve blockade in chronic migraine: A placebo-controlled study

2016 ◽  
Vol 136 (2) ◽  
pp. 138-144 ◽  
Author(s):  
H. L. Gul ◽  
A. O. Ozon ◽  
O. Karadas ◽  
G. Koc ◽  
L. E. Inan
2015 ◽  
Vol 132 (4) ◽  
pp. 270-277 ◽  
Author(s):  
L. E. Inan ◽  
N. Inan ◽  
Ö. Karadaş ◽  
H. L. Gül ◽  
A. K. Erdemoğlu ◽  
...  

Cephalalgia ◽  
2016 ◽  
Vol 36 (11) ◽  
pp. 1095-1095 ◽  
Author(s):  
Levent Ertugrul Inan

2021 ◽  
Vol 26 (4) ◽  
pp. 731-736
Author(s):  
Tülin Aktürk ◽  
Hikmet Saçmacı ◽  
Hanzade Aybüke Ünal Artık ◽  
Nermin Tanık ◽  
Levent Ertuğrul İnan

Objectives: The aim of this study was to compare greater occipital nerve blockade (GONB) alone and GONB combined with lesser occipital nerve blockade (LONB) in chronic migraine patients. Methods: Patients were randomly divided into two groups: Group A consisted of 22 patients who received only GONB; while Group B consisted of 20 patients who underwent GONB and LONB. The demographics and clinical characteristics of the patients were evaluated. The injections were given unilaterally and to the side where the subjects experienced greater pain. GONB with or without LONB was performed on each patient once a week for 4 weeks and then two more times a month apart; 6 times in total. The number of headache days, severity of attacks and duration of headache episodes was recorded from headache diaries before treatment and the on the first, second and third month following the start of treatment. Treatment efficiencies were evaluated within and between the groups. Results: The duration of pretreatment headaches was significantly longer in Group B (p=0.032). There were no differences between the groups in terms of other demographic and clinical characteristics. When the treatments applied in group A and group B were evaluated separately compared to the control group, there was a statistically significant decrease in the number of headache days, VAS scores and headache duration (p <0.05). When the results of treatment between groups were compared, there was no difference in terms of the number of headache days and VAS scores. Although the duration of headache was longer in the pretreatment period in group B, this difference disappeared on posttreatment follow-up (p>0.05). Conclusions: This study suggests that there is no difference in the number of headache days or headache intensity between GONB alone or in combination with LONB in chronic migraine patients. GONB combined with LONB in patients may be more effective than GONB alone when headaches of longer duration are present.


Cephalalgia ◽  
2014 ◽  
Vol 35 (11) ◽  
pp. 959-968 ◽  
Author(s):  
Esma Dilli ◽  
Rashmi Halker ◽  
Bert Vargas ◽  
Joseph Hentz ◽  
Teresa Radam ◽  
...  

Background Occipital nerve (ON) injections with corticosteroids and/or local anesthetics have been employed for the acute and preventive treatment of migraine for decades. However, to date there is no randomized, placebo-controlled evidence to support the use of occipital nerve block (ONB) for the prevention of migraine. Objective The objective of this article is to determine the efficacy of ONB with local anesthetic and corticosteroid for the preventive treatment of migraine. Participants and methods Patients between 18 and 75 years old with ICHD-II-defined episodic (> 1 attack per week) or chronic migraine (modified ICHD-II as patients with > 10 days with consumption of acute medications were permitted into the study) were randomized to receive either 2.5 ml 0.5% bupivacaine plus 0.5 ml (20 mg) methylprednisolone over the ipsilateral (unilateral headache) or bilateral (bilateral headache) ON or 2.75 ml normal saline plus 0.25 ml 1% lidocaine without epinephrine (placebo). Patients completed a one-month headache diary prior to and after the double-blind injection. The primary outcome measure was defined as a 50% or greater reduction in the frequency of days with moderate or severe migraine headache in the four-week post-injection compared to the four-week pre-injection baseline period. Results Thirty-four patients received active and 35 patients received placebo treatment. Because of missing data, the full analysis of 33 patients in the active and 30 patients in the placebo group was analyzed for efficacy. In the active and placebo groups respectively, the mean frequency of at least moderate (mean 9.8 versus 9.5) and severe (3.6 versus 4.3) migraine days and acute medication days (7.9 versus 10.0) were not substantially different at baseline. The percentage of patients with at least a 50% reduction in the frequency of moderate or severe headache days was 30% for both groups (10/30 vs nine of 30, Δ 0.00, 95% CI –0.22 to 0.23). Conclusions Greater ONB does not reduce the frequency of moderate to severe migraine days in patients with episodic or chronic migraine compared to placebo. The study was registered with ClinicalTrial.gov (NCT00915473).


2008 ◽  
Vol 66 (1) ◽  
pp. 74-76 ◽  
Author(s):  
Fabrizio Di Stani ◽  
Elcio Juliato Piovesan ◽  
Lorena Scattoni ◽  
Gianluca Bruti ◽  
Lineu Cesar Werneck

2018 ◽  
Vol 138 (3) ◽  
pp. 212-218 ◽  
Author(s):  
O. Korucu ◽  
S. Dagar ◽  
Ş. K. Çorbacioglu ◽  
E. Emektar ◽  
Y. Cevik

Sign in / Sign up

Export Citation Format

Share Document