scholarly journals Placental pulsatility index: a new, more sensitive parameter for predicting adverse outcome in pregnancies suspected of fetal growth restriction

2017 ◽  
Vol 96 (2) ◽  
pp. 216-222 ◽  
Author(s):  
Saemundur Gudmundsson ◽  
Kari Flo ◽  
Gisela Ghosh ◽  
Tom Wilsgaard ◽  
Ganesh Acharya
2012 ◽  
Vol 2 (3) ◽  
pp. 302-303 ◽  
Author(s):  
J. Sibiude ◽  
M.-D. Dionne ◽  
J. Guibourdenche ◽  
C. Le Ray ◽  
O. Anselem ◽  
...  

2018 ◽  
Vol 218 (1) ◽  
pp. S297-S298
Author(s):  
Ofer Beharier ◽  
shani Swissa ◽  
Irit Szaingurten-Solodkin ◽  
Asnat Walfisch ◽  
shimrt Yaniv-Salem ◽  
...  

2019 ◽  
Vol 220 (1) ◽  
pp. S286
Author(s):  
Jonathan G. Steller ◽  
Diane Gumina ◽  
Allison Gillan ◽  
Shane Reeves ◽  
John Hobbins ◽  
...  

2013 ◽  
Vol 208 (1) ◽  
pp. S171
Author(s):  
Anthony Odibo ◽  
Katherine Goetzinger ◽  
Alison Cahill ◽  
Linda Odibo ◽  
George Macones

2013 ◽  
Vol 2013 ◽  
pp. 1-12 ◽  
Author(s):  
Ilona Hromadnikova ◽  
Katerina Kotlabova ◽  
Marketa Ondrackova ◽  
Andrea Kestlerova ◽  
Veronika Novotna ◽  
...  

The objective of the study was to identify the profile of circulating C19MC microRNAs (miR-516-5p, miR-517*, miR-518b, miR-520a*, miR-520h, miR-525, and miR-526a) in patients with established preeclampsia (n=63), fetal growth restriction (n=27), and gestational hypertension (n=23). We examined the correlation between plasmatic concentrations and expression levels of microRNAs and the severity of the disease with respect to clinical signs, requirements for the delivery, and Doppler ultrasound parameters. Using absolute and relative quantification approaches, increased extracellular C19MC microRNA levels (miR-516-5p,P=0.037,P=0.009; miR-517*,P=0.033,P=0.043; miR-520a*,P=0.001,P=0.009; miR-525,P=0.026,P=0.01; miR-526a,P=0.03,P=0.035) were detected in patients with preeclampsia. The association analysis pointed to no relationship between C19MC microRNA plasmatic concentrations and expression profile and identified risk factors for a poorer perinatal outcome. However, the dependence between the levels of plasmatic C19MC microRNAs and the pulsatility index in the middle cerebral artery and the values of cerebroplacental ratio was demonstrated. The study brought the interesting finding that the upregulation of miR-516-5p, miR-517*, miR-520a*, miR-525, and miR-526a is a characteristic phenomenon of established preeclampsia.


2002 ◽  
Vol 13 (4) ◽  
pp. 249-259 ◽  
Author(s):  
Jason Gardosi

With the ascendancy of biophysical assessment with Doppler velocimetry, and the establishment of routine scan dating in early pregnancy, there needs to be a radical re-think of the role of ultrasound biometry in the definition and assessment of fetal growth restriction (FGR).Doppler flow velocimetry of the umbilical artery has proven its value in defining the FGR fetus. It is more useful than cardiotocography (CTG) or biophysical profile scoring. However, the sensitivity of any test depends on the prevalence of the condition being looked for. While Doppler is of value in fetuses which are small-for-gestational age (SGA), it is less useful in predicting growth restriction or adverse outcome in the general population. The question is therefore, how to detect those pregnancies for which further fetal assessment is indicated.


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