scholarly journals Healthy Volunteers in First in Human Oncology Drug Development for Small Molecules

2021 ◽  
Author(s):  
Begoña Heras ◽  
Dalila Bouyoucef‐Cherchalli ◽  
Lesley Reeve ◽  
Andreas Reichl ◽  
Debra Mandarino ◽  
...  
Keyword(s):  
Drug Development ◽  
Healthy Volunteers ◽  
Small Molecules ◽  
Oncology Drug ◽  
Oncology Drug Development

scholarly journals Pivotal Considerations for Optimal Deployment of Healthy Volunteers in Oncology Drug Development

2019 ◽  
Vol 13 (1) ◽  
pp. 31-40
Author(s):  
Mariam A. Ahmed ◽  
Chirag Patel ◽  
Nicole Drezner ◽  
Whitney Helms ◽  
Weiwei Tan ◽  
...  
Keyword(s):  
Drug Development ◽  
Healthy Volunteers ◽  
Oncology Drug ◽  
Optimal Deployment ◽  
Oncology Drug Development

scholarly journals Next generation oncology drug development: opportunities and challenges

2009 ◽  
Vol 6 (5) ◽  
pp. 259-265 ◽  
Author(s):  
Martin E. Gutierrez ◽  
Shivaani Kummar ◽  
Giuseppe Giaccone
Keyword(s):  
Drug Development ◽  
Next Generation ◽  
Oncology Drug ◽  
Oncology Drug Development

scholarly journals Patient-derived tumour xenografts as models for oncology drug development

2012 ◽  
Vol 9 (6) ◽  
pp. 338-350 ◽  
Author(s):  
John J. Tentler ◽  
Aik Choon Tan ◽  
Colin D. Weekes ◽  
Antonio Jimeno ◽  
Stephen Leong ◽  
...  
Keyword(s):  
Drug Development ◽  
Oncology Drug ◽  
Oncology Drug Development ◽  
Tumour Xenografts

Cardiovascular Safety Monitoring During Oncology Drug Development and Therapy

2014 ◽  
Vol 21 (6) ◽  
pp. 512-522 ◽  
Author(s):  
J. Rick Turner ◽  
Gopi Krishna Panicker ◽  
Dilip R. Karnad ◽  
Christopher H. Cabell ◽  
Ronald Lieberman ◽  
...  
Keyword(s):  
Drug Development ◽  
Safety Monitoring ◽  
Cardiovascular Safety ◽  
Oncology Drug ◽  
Oncology Drug Development

Abstract 529: Characterization of a humanized TLR8 mouse model and its application in immuno-oncology drug development

2021 ◽  
Author(s):  
Hongjuan Zhang ◽  
Ruilin Sun ◽  
Annie X. An ◽  
Henry Q.x Li ◽  
Davy Xuesong Ouyang
Keyword(s):  
Mouse Model ◽  
Drug Development ◽  
Oncology Drug ◽  
Oncology Drug Development

Opportunities posed by novel patient selection biomarker approaches in oncology drug development: going beyond the cytotoxics

2008 ◽  
Vol 2 (2) ◽  
pp. 147-153 ◽  
Author(s):  
Grant Sellar ◽  
John D Alvarez ◽  
Frank Loganzo ◽  
Richat Abbas ◽  
Fred Immermann ◽  
...  
Keyword(s):  
Drug Development ◽  
Patient Selection ◽  
Oncology Drug ◽  
Oncology Drug Development
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