Transcatheter Aortic Valve Implantation in Surgically Repaired Double Outlet Right Ventricle

2013 ◽  
Vol 9 (5) ◽  
pp. E153-E157 ◽  
Author(s):  
Amit Keswani ◽  
Anil Verma ◽  
Kristen Dann ◽  
Laurie Ventura ◽  
Victor Lucas ◽  
...  

2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
A Calin ◽  
D Cadil ◽  
C.A Parasca ◽  
A.D Mateescu ◽  
M Rosca ◽  
...  

Abstract Background Transcatheter aortic valve implantation (TAVI) improves not only left heart remodeling but also has an upstream effect on the right ventricle and pulmonary vasculature. Right ventricle (RV) to pulmonary artery (PA) coupling, a parameter which integrates RV systolic performance at a given degree of afterload, was associated with all-cause mortality in these patients (pts). Our aim was to evaluate the short-term effect of TAVI on RV-PA coupling and the main determinants of RV-PA coupling in pts with aortic stenosis (AS) undergoing transfemoral TAVI. Methods We have prospectively enrolled 102 consecutive pts (76±8 years, 57 men) with severe AS undergoing TAVI. All pts underwent a comprehensive echocardiogram both before and 30 days after TAVI, including speckle tracking echocardiography (STE) for myocardial deformation analysis. Peak values of global longitudinal left ventricular strain (GLS), left atrial strain (LAε, reservoir function), and late diastolic LA strain rate (ASr, contractile function) were measured. The ratio of tricuspid annular plane systolic excursion (TAPSE) to PA systolic pressure (PASP) was used as an estimate of RV-PA coupling. Results Compared with baseline, there was a significant increase in LV ejection fraction after TAVI (54±12% vs 50±13%, p=0.04), a significant reduction in LV mass (147±35 vs 171±44 g/m2, p<0.001) and increase in absolute GLS values (14±3% vs 12±5%, p=0.007). Indexed LA volumes decreased (49±19 vs 55±19 ml/m2, p=0.03) while both global LAε and ASr improved significantly after TAVI (16±8% vs 13±7%, p=0.01 and −1.2±0.6 vs −0.9±0.6%, p=0.01). A significant improvement of TAPSE/PASP values (0.069±0.026 vs 0.057±0.025 cm/mm Hg, p<0.001) was found after TAVI, indicating an enhanced RV-PA coupling. In multivariable regression analysis global LAε was independently related to RV-PA coupling, both before and after TAVI (R=0.54, p=0.003 and R= 0.39, p<0.001). The increase in RV-PA coupling was significantly related to the increase in LAε (p=0.005). Conclusions Our results confirm that relief of aortic valve obstruction by TAVI has beneficial effects on the RV-PA coupling, that occur early after intervention. This is accompanied by a significant improvement in LV and LA deformation. Moreover, there is a significant correlation between LA function and RV-PA coupling both before and after TAVI. Enhanced RV-PA coupling after TAVI is related to improved LA strain, suggesting the contribution of LA function in modulating right heart function in this setting. Funding Acknowledgement Type of funding source: None



2020 ◽  
Vol 37 (4) ◽  
pp. 586-591
Author(s):  
Ana Pardo Sanz ◽  
Ciro Santoro ◽  
Rocío Hinojar ◽  
Luisa Salido ◽  
Ez‐Alddin Rajjoub ◽  
...  




2020 ◽  
pp. 79-86
Author(s):  
А.Е. Комлев ◽  
Т.Э. Имаев ◽  
М.А. Саидова ◽  
Д.В. Певзнер ◽  
Э.В. Курилина

В статье представлен клинический случай транскатетерной имплантации аортального клапана (ТИАК) пациенту 71 года с критическим аортальным стенозом в стадии систолической дисфункции с развитием истинного кардиогенного шока. Операция была выполнена в условиях продолжающейся внутриаортальной баллонной контрпульсации. Несмотря на технический успех ТИАК, пациент скончался в раннем послеоперационном периоде при явлениях острой правожелудочковой недостаточности. Авторами проводится анализ особенностей лечения пациента и причин, повлиявших на неблагоприятный исход, а также обсуждается влияние патологии правого желудочка на результаты транс катетерной коррекции аортального стеноза. Clinical case of transcatheter aortic valve implantation (TAVI) in 71 years old male with decompensated critical aortic stenosis in the setting of cardiogenic shock is presented in the paper. The procedure was performed under use of continuous intra-aortic balloon pump. Despite of technical success of TAVI the patient passed away early after procedure with clinical signs of right ventricle failure. The authors analyze the treatment strategy in the context of unfavorable outcome as well as the impact of right ventricle disease on results of TAVI







2010 ◽  
Vol 58 (S 01) ◽  
Author(s):  
D Wendt ◽  
P Tossios ◽  
M Thielmann ◽  
P Kahlert ◽  
H Eggebrecht ◽  
...  


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