Difficulties in auditory organization as a cause of reading backwardness? An auditory neuroscience perspective

The dorsal (DCIC) and lateral cortices (LCIC) of the inferior colliculus are major targets of the auditory and non-auditory cortical areas, suggesting a role in complex multimodal information processing. However, relatively little is known about their functional organization. We utilized in vivo two-photon Ca2+ imaging in awake mice expressing GCaMP6s in GABAergic or non-GABAergic neurons in the IC to investigate their spatial organization. We found different classes of temporal responses, which we confirmed with simultaneous juxtacellular electrophysiology. Both GABAergic and non-GABAergic neurons showed spatial microheterogeneity in their temporal responses. In contrast, a robust, double rostromedial-caudolateral gradient of frequency tuning was conserved between the two groups, and even among the subclasses. This, together with the existence of a subset of neurons sensitive to spontaneous movements, provides functional evidence for redefining the border between DCIC and LCIC.

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Auditory Neuroscience: Unravelling How the Brain Gives Sound Meaning

Current Biology ◽

10.1016/j.cub.2020.03.041 ◽

2020 ◽

Vol 30 (9) ◽

pp. R400-R402

Author(s):

Jennifer K. Bizley

Keyword(s):

Auditory Neuroscience ◽

The Brain

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Translational Perspectives in Auditory Neuroscience: Normal Aspects of Hearing

International Journal of Audiology ◽

10.3109/14992027.2014.956902 ◽

2014 ◽

Vol 53 (11) ◽

pp. 839-839

Author(s):

Anthony T. Cacace

Keyword(s):

Auditory Neuroscience

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Evolving perspectives on the sources of the frequency-following response

Nature Communications ◽

10.1038/s41467-019-13003-w ◽

2019 ◽

Vol 10 (1) ◽

Cited By ~ 15

Author(s):

Emily B. J. Coffey ◽

Trent Nicol ◽

Travis White-Schwoch ◽

Bharath Chandrasekaran ◽

Jennifer Krizman ◽

...

Keyword(s):

Neural Encoding ◽

Complex Sounds ◽

Frequency Following Response ◽

Auditory Neuroscience ◽

Non Invasive ◽

Auditory Processes ◽

The Brain

Abstract The auditory frequency-following response (FFR) is a non-invasive index of the fidelity of sound encoding in the brain, and is used to study the integrity, plasticity, and behavioral relevance of the neural encoding of sound. In this Perspective, we review recent evidence suggesting that, in humans, the FFR arises from multiple cortical and subcortical sources, not just subcortically as previously believed, and we illustrate how the FFR to complex sounds can enhance the wider field of auditory neuroscience. Far from being of use only to study basic auditory processes, the FFR is an uncommonly multifaceted response yielding a wealth of information, with much yet to be tapped.

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Advances in auditory neuroscience

International Journal of Psychophysiology ◽

10.1016/j.ijpsycho.2015.01.008 ◽

2015 ◽

Vol 95 (2) ◽

pp. 63-64 ◽

Cited By ~ 1

Author(s):

Elyse S. Sussman ◽

Mitchell Steinschneider

Keyword(s):

Auditory Neuroscience

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Why otoliths? Insights from inner ear physiology and fisheries biology

Marine and Freshwater Research ◽

10.1071/mf04267 ◽

2005 ◽

Vol 56 (5) ◽

pp. 497 ◽

Cited By ~ 134

Author(s):

Arthur N. Popper ◽

John Ramcharitar ◽

Steven E. Campana

Keyword(s):

Inner Ear ◽

Functional Significance ◽

Basic Structure ◽

Sensory Epithelium ◽

Teleost Fishes ◽

Major Purpose ◽

Auditory Neuroscience ◽

Otolith Morphology ◽

Fisheries Biology ◽

Otolith Size

Otoliths are of interest to investigators from several disciplines including systematics, auditory neuroscience, and fisheries. However, there is often very little sharing of information or ideas about otoliths across disciplines despite similarities in the questions raised by different groups of investigators. A major purpose of this paper is to present otolith-related questions common to all disciplines and then demonstrate that the issues are not only similar but also that more frequent interactions would be mutually beneficial. Because otoliths evolved as part of the inner ear to serve the senses of balance and hearing, we first discuss the basic structure of the ear. We then raise several questions that deal with the structure and patterns of otolith morphology and how changes in otoliths with fish age affect hearing and balance. More specifically, we ask about the significance of otolith size and how this might affect ear function; the growth of otoliths and how hearing and balance may or may not change with growth; the significance of different otolith shapes with respect to ear function; the functional significance of otoliths that do not contact the complete sensory epithelium; and why teleost fishes have otoliths and not the otoconia found in virtually all other extant vertebrates.

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