Sensitization/tolerance profile of betamethasone sodium phosphate in patients with contact allergy to budesonide

2020 ◽  
Vol 33 (6) ◽  
Author(s):  
Katharina Hansel ◽  
Rossella Marietti ◽  
Marta Tramontana ◽  
Leonardo Bianchi ◽  
Luigi Rigano ◽  
...  
Keyword(s):  
Sodium Phosphate ◽  
Contact Allergy ◽  
Betamethasone Sodium Phosphate

Comparison of the Particle Sizes of Different Steroids and the Effect of Dilution

2007 ◽  
Vol 106 (2) ◽  
pp. 331-338 ◽  
Author(s):  
Honorio T. Benzon ◽  
Teng-Leong Chew ◽  
Robert J. McCarthy ◽  
Hubert A. Benzon ◽  
David R. Walega
Keyword(s):  
Sodium Phosphate ◽  
Laser Scanning ◽  
Pure Liquid ◽  
Particle Sizes ◽  
Bonferroni Correction ◽  
Chi Square ◽  
Laser Scanning Confocal Microscope ◽  
Epidural Steroid Injections ◽  
Epidural Steroid ◽  
Betamethasone Sodium Phosphate

Background Central nervous system injuries after transforaminal epidural steroid injections have been ascribed to occlusion of the blood vessels supplying the spinal cord and brain by the particulate steroid. Methods The authors compared the sizes of the particles of the steroids methylprednisolone acetate, triamcinolone acetonide, dexamethasone sodium phosphate, betamethasone sodium phosphate/betamethasone acetate (both Celestone Soluspan; Schering-Plough, Kenilworth, NJ, the commercial betamethasone; and betamethasone repository, a betamethasone preparation that can be ordered from a compounding company), and betamethasone sodium phosphate. Both undiluted and diluted samples were examined. The samples were examined with a laser scanning confocal microscope, and images were analyzed and measured. The particles were categorized (or tabulated) into groups: 0-20, 21-50, 51-1000, and greater than 1000 mu. Chi-square analyses, with Bonferroni correction, were used to compare the proportion of particles among the undiluted and diluted drug formulations. Results Dexamethasone and betamethasone sodium phosphate were pure liquid. The proportion of larger particles was significantly greater in the methylprednisolone and the compounded betamethasone preparations compared with the commercial betamethasone. There was no statistical difference between the commercial betamethasone and triamcinolone, although betamethasone had a smaller percentage of the larger particles. Increased dilution of the compounded betamethasone with lidocaine decreased the percentage of the larger particles, whereas increased dilution of methylprednisolone 80 mg/ml with saline increased the proportion of larger particles. Conclusion Commercial betamethasone is the recommended preparation if a nonsoluble steroid is preferred. Dexamethasone is a nonparticulate steroid, but its routine use awaits further studies on its safety and efficacy.

Betamethasone-sodium-phosphate/dexamethasone

2020 ◽  
Vol 1830 (1) ◽  
pp. 84-84
Keyword(s):  
Sodium Phosphate ◽  
Betamethasone Sodium Phosphate

Betamethasone sodium phosphate/triamcinolone

2018 ◽  
Vol 1727 (1) ◽  
pp. 62-62
Keyword(s):  
Sodium Phosphate ◽  
Betamethasone Sodium Phosphate

Determination of Betamethasone Sodium Phosphate in Pharmaceuticals by Potentiometric Membrane Sensor Based on Its Lidocaine Ion Pair

2013 ◽  
Vol 68 (10) ◽  
pp. 995-1000
Author(s):  
M. Giahi ◽  
O. Marvi ◽  
F. Safari ◽  
B. Chahkandi
Keyword(s):  
Sodium Phosphate ◽  
Ion Pair ◽  
Membrane Sensor ◽  
Betamethasone Sodium Phosphate

Preparation and characterization of (betamethasone sodium phosphate intercalated layered double hydroxide)@liposome nanocomposites

2017 ◽  
Vol 529 ◽  
pp. 824-831 ◽  
Author(s):  
Yaping Zhang ◽  
Xiaowen Wu ◽  
Haiping Li ◽  
Na Du ◽  
Shue Song ◽  
...  
Keyword(s):  
Layered Double Hydroxide ◽  
Sodium Phosphate ◽  
Double Hydroxide ◽  
Betamethasone Sodium Phosphate
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