Long‐acting antipsychotic medication as first‐line treatment of first‐episode psychosis with comorbid substance use disorder

2019 ◽  
Vol 14 (1) ◽  
pp. 69-79 ◽  
Author(s):  
Amal Abdel‐Baki ◽  
Dominic Thibault ◽  
Sofia Medrano ◽  
Emmanuel Stip ◽  
Martin Ladouceur ◽  
...  
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Antipsychotic Medication ◽  
First Episode Psychosis ◽  
First Episode ◽  
Line Treatment ◽  
First Line ◽  
Episode Psychosis ◽  
Long Acting ◽  
First Line Treatment

scholarly journals 4.2 Striatal Glutamate as Biomarker of Clinical Response to First-Line Treatment in Antipsychotic-naïve, First-Episode Psychosis Patients

2017 ◽  
Vol 43 (suppl_1) ◽  
pp. S5-S5
Author(s):  
Camilo de la Fuente-Sandoval ◽  
Francisco Reyes-Madrigal ◽  
Pablo León-Ortiz ◽  
Ariel Graff-Guerrero
Keyword(s):  
Clinical Response ◽  
First Episode Psychosis ◽  
First Episode ◽  
Line Treatment ◽  
First Line ◽  
Episode Psychosis ◽  
First Line Treatment

Specialized assertive community treatment intervention for homeless youth with first episode psychosis and substance use disorder: A 2‐year follow‐up study

2019 ◽  
Vol 14 (2) ◽  
pp. 203-210 ◽  
Author(s):  
Virginie Doré‐Gauthier ◽  
Jean‐Philippe Miron ◽  
Dider Jutras‐Aswad ◽  
Clairélaine Ouellet‐Plamondon ◽  
Amal Abdel‐Baki
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Homeless Youth ◽  
First Episode Psychosis ◽  
Community Treatment ◽  
First Episode ◽  
Treatment Intervention ◽  
Follow Up Study ◽  
Episode Psychosis

Symptomatic and functional outcomes of substance use disorder persistence 2 years after admission to a first-episode psychosis program

2017 ◽  
Vol 247 ◽  
pp. 113-119 ◽  
Author(s):  
Amal Abdel-Baki ◽  
Clairélaine Ouellet-Plamondon ◽  
Émilie Salvat ◽  
Kawthar Grar ◽  
Stéphane Potvin
Keyword(s):  
Substance Use ◽  
Substance Use Disorder ◽  
Functional Outcomes ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

IMPACT OF SUBSTANCE USE DISORDER ON FUNCTIONAL OUTCOME IN FIRST-EPISODE PSYCHOSIS: A 2 YEARS PROSPECTIVE STUDY WITHIN THE UNIVERSITé DE MONTRéAL NETWORK

2010 ◽  
Vol 117 (2-3) ◽  
pp. 424
Author(s):  
Emilie Salvat ◽  
Amal Abdel-Baki ◽  
Luc Nicole ◽  
Stéphane Potvin ◽  
Clairélaine Ouellet-Plamondon ◽  
...  
Keyword(s):  
Substance Use ◽  
Prospective Study ◽  
Functional Outcome ◽  
Substance Use Disorder ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis

scholarly journals First episode psychosis and comorbid ADHD, autism and intellectual disability

2019 ◽  
Vol 55 ◽  
pp. 18-22 ◽  
Author(s):  
Pontus Strålin ◽  
Jerker Hetta
Keyword(s):  
Substance Use ◽  
Intellectual Disability ◽  
Substance Use Disorders ◽  
Antipsychotic Medication ◽  
Neurodevelopmental Disorders ◽  
First Episode Psychosis ◽  
First Episode ◽  
Episode Psychosis ◽  
Self Harm ◽  
Comorbid Adhd

AbstractBackground:Comorbidity between neurodevelopmental disorders and psychotic disorders is common, but little is known about how neurodevelopmental disorders influence the presentation and outcome of first episode psychosis.Methods:A nation-wide cohort (n = 2091) with a first hospitalization for psychosis between 2007–2011 and at ages between 16–25 at intake was identified from Swedish population registries. Comorbid diagnoses of neurodevelopmental disorders were identified at first psychosis hospitalization and for ADHD also by dispensations of psychostimulants before the first psychosis hospitalization.Data from the registers on hospitalizations and dispensations of antipsychotic and psychostimulant medications during the year before and 2 years after the first psychosis hospitalization were analysed. Self-harm and substance use disorders were identified by ICD10 codes at hospitalizations.Results:2.5% of the cohort was identified with a diagnosis of intellectual disability, 5.0% with autism and 8.1% with ADHD. A larger proportion of cases with Autism (OR = 1.8, p < 0.05) and intellectual disability (OR = 3.1, p < 0.01) were using antipsychotic medication year 2 compared to the rest of the cohort. Delusional disorder was more common in the autism group (OR = 2.3, p < 0.05) at first psychosis hospitalization. ADHD was associated with higher risks for substance use disorders and self-harm both before and after the first psychosis hospitalization. Year 2 substance use disorder had a OR = 2.6 (p < 0.001) and self-harm OR = 4.1 (p < 0.001).Conclusions:Psychosis with comorbid ADHD is associated with high risks for substance use disorders and for self-harm, while psychosis with comorbid autism and intellectual disability is associated with longer treatment and higher doses of antipsychotic medication.

Sign in / Sign up

Export Citation Format

Share Document