Clinical, radiological, and pathological features of idiopathic and secondary interstitial pneumonia cases with pleuroparenchymal fibroelastosis undergoing lung transplantation

2021 ◽  
Author(s):  
Naoya Ikegami ◽  
Naoki Nakajima ◽  
Akihiko Yoshizawa ◽  
Tomohiro Handa ◽  
Toyofumi Chen‐Yoshikawa ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Interstitial Pneumonia ◽  
Pathological Features ◽  
Pleuroparenchymal Fibroelastosis

scholarly journals Pleuroparenchymal fibroelastosis: report of two cases in Brazil

2017 ◽  
Vol 43 (1) ◽  
pp. 72-75 ◽  
Author(s):  
Paula Silva Gomes ◽  
Christina Shiang ◽  
Gilberto Szarf ◽  
Ester Nei Aparecida Martins Coletta ◽  
Carlos Alberto de Castro Pereira
Keyword(s):  
Lung Transplantation ◽  
Lung Disease ◽  
Interstitial Pneumonia ◽  
Lung Biopsy ◽  
Hypersensitivity Pneumonitis ◽  
Lower Lobe ◽  
Pleuroparenchymal Fibroelastosis ◽  
Reticular Pattern ◽  
Domestic Birds ◽  
History Of

ABSTRACT Pleuroparenchymal fibroelastosis (PPFE) is a rare lung disease. It can be idiopathic or associated with any one of various conditions. To our knowledge, this is the first report of two cases of PPFE in Brazil. Our first patient presented with pleural and subpleural fibrosis in the upper lobes; a spiculated nodule in the left upper lobe; and a mild reticular pattern in the lower lobes. Surgical lung biopsy revealed PPFE in the upper lobes, including the nodule, and unclassified interstitial pneumonia in the left lower lobe. Our second patient had a history of exposure to domestic birds, indicating a risk of hypersensitivity pneumonitis, and presented with advanced lung disease, predominantly in the upper lobes, together with subpleural fibrosis.That patient underwent lung transplantation. In the explant specimen, PPFE and granulomas were identified, suggesting hypersensitivity pneumonitis as an associated cause.

Clinical and pathological features of idiopathic and secondary pleuroparenchymal fibroelastosis in patients undergoing lung transplantation

2019 ◽  
Author(s):  
Naoya Ikegami ◽  
Naoki Nakajima ◽  
Kiminobu Tanizawa ◽  
Akihiko Yoshizawa ◽  
Tomohiro Handa ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Pathological Features ◽  
Pleuroparenchymal Fibroelastosis ◽  
Clinical And Pathological Features

Predicting Survival of Lung Transplantation Candidates With Idiopathic Interstitial Pneumonia

CHEST Journal ◽  
2002 ◽  
Vol 122 (3) ◽  
pp. 779-784 ◽  
Author(s):  
Suzanne J. Timmer ◽  
Amir M. Karamzadeh ◽  
G.L. Yung ◽  
Jolene Kriett ◽  
Stewart W. Jamieson ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Interstitial Pneumonia ◽  
Idiopathic Interstitial Pneumonia

Usual Interstitial Pneumonia Pattern in the Lower Lung Lobes as a Prognostic Factor in Idiopathic Pleuroparenchymal Fibroelastosis

Respiration ◽  
2018 ◽  
Vol 97 (4) ◽  
pp. 319-328 ◽  
Author(s):  
Motoyasu Kato ◽  
Shinichi Sasaki ◽  
Kana Kurokawa ◽  
Takahiro Nakamura ◽  
Tomoko Yamada ◽  
...  
Keyword(s):  
Prognostic Factor ◽  
Interstitial Pneumonia ◽  
Usual Interstitial Pneumonia ◽  
Pleuroparenchymal Fibroelastosis ◽  
Lower Lung ◽  
Lung Lobes

scholarly journals The Pathological Features of Bronchoscopic Lung Volume Reduction Using Sealant Treatment Assessed in Lung Explants of Patients Who Underwent Lung Transplantation

Respiration ◽  
2013 ◽  
Vol 86 (2) ◽  
pp. 143-144 ◽  
Author(s):  
Oren Fruchter ◽  
Ludmila Fridel ◽  
Mordechai R. Kramer
Keyword(s):  
Lung Transplantation ◽  
Lung Volume ◽  
Volume Reduction ◽  
Pathological Features ◽  
Lung Volume Reduction

scholarly journals Idiopathic pleuroparenchymal fibroelastosis – A rare idiopathic interstitial pneumonia

2016 ◽  
Vol 17 ◽  
pp. 8-11 ◽  
Author(s):  
Balamugesh Thangakunam ◽  
Barney T.J. Isaac ◽  
Devasahayam Jesudas Christopher ◽  
Deepak Burad
Keyword(s):  
Interstitial Pneumonia ◽  
Idiopathic Interstitial Pneumonia ◽  
Pleuroparenchymal Fibroelastosis

The Recurrence of Desquamative Interstitial Pneumonia Post-Lung Transplantation.

2009 ◽  
Author(s):  
E Kluka ◽  
J Jessurun ◽  
M Hertz ◽  
S Shumway ◽  
T Whelan
Keyword(s):  
Lung Transplantation ◽  
Interstitial Pneumonia

Pleuroparenchymal fibroelastosis and non-specific interstitial pneumonia: frequent pulmonary sequelae of haematopoietic stem cell transplantation

2014 ◽  
Vol 66 (4) ◽  
pp. 536-544 ◽  
Author(s):  
Yasuhide Takeuchi ◽  
Aya Miyagawa-Hayashino ◽  
Fengshi Chen ◽  
Takeshi Kubo ◽  
Tomohiro Handa ◽  
...  
Keyword(s):  
Stem Cell ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Interstitial Pneumonia ◽  
Haematopoietic Stem Cell Transplantation ◽  
Haematopoietic Stem Cell ◽  
Pleuroparenchymal Fibroelastosis

scholarly journals Pleuroparenchymal fibroelastosis presenting with pneumothorax

2018 ◽  
Vol 6 ◽  
pp. 2050313X1876285 ◽  
Author(s):  
Yen-Yu Lin ◽  
Wen-Hu Hsu ◽  
Mei-Han Wu ◽  
Teh-Ying Chou
Keyword(s):  
Interstitial Pneumonia ◽  
Progressive Disease ◽  
Inflammatory Cell ◽  
Clinical Presentation ◽  
Usual Interstitial Pneumonia ◽  
Distinct Type ◽  
Pleuroparenchymal Fibroelastosis ◽  
Biopsy Specimens ◽  
Wedge Biopsy ◽  
Pleural Involvement

A 47-year-old woman presented with spontaneous right side pneumothorax. Image studies showed consolidations and reticular opacities involving the pleural and subpleural regions of bilateral lungs. Wedge biopsy specimens of right upper, middle and lower lobes showed fibrosis of the visceral pleura and subpleural area in all three lobes, more significant in the upper lobe. Elastic Van Gieson stain showed a pattern of alveolar septal elastosis with intra-alveolar fibrosis. The clinical presentation and pathological findings are compatible with pleuroparenchymal fibroelastosis, a rare and distinct type of interstitial lung disease. This entity is different from usual interstitial pneumonia by its relationship to pleura, upper lobe predominance and temporal homogeneity. It is different from non-specific interstitial pneumonia by its pleural involvement and scanty inflammatory cell infiltration. Pleuroparenchymal fibroelastosis is a slowly progressive disease; about half of the patients die in 10 years. No curative treatment is available at present time.

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