What's new in dermoscopy of Bowen's disease: two new dermoscopic signs and its differential diagnosis

Circumscribed palmoplantar hypokeratosis is a recently recognized dermatosis and rarely reported. It was first described in 2002 and is characterized by localized loss of the horny layer in the palmoplantar area. This dermatosis is clinically presented with a sharply circumscribed, reddish and asymptomatic plaque with slightly depressed surface localized on the palms or the soles. The clinical differential diagnosis includes mainly porokeratosis and Bowen's disease. Its pathogenesis remains unknown, but studies have proposed a human papillomavirus induced disease or a localized keratinization disorder in the palmoplantar area. We report herein two cases of patients with lesions clinically and microscopically compatible with the diagnosis of circumscribed palmoplantar hypokeratosis. We also present a brief literature review of the etiopathogenic hyphoteses of this dermatosis.

Download Full-text

A challenging case of pigmented Bowen’s disease and differential diagnosis of pagetoid pigmented skin lesions

Pathologica ◽

10.32074/1591-951x-21-19 ◽

2019 ◽

Vol 111 (3) ◽

pp. 98-104

Author(s):

V. Caputo ◽

E. Caselli ◽

M. Ribotta ◽

E. Bonoldi

Keyword(s):

Differential Diagnosis ◽

Skin Lesions ◽

Bowen’S Disease ◽

Bowen's Disease ◽

Pigmented Skin Lesions

Download Full-text

Phasor–FLIM as a Screening Tool for the Differential Diagnosis of Actinic Keratosis, Bowen’s Disease, and Basal Cell Carcinoma

Analytical Chemistry ◽

10.1021/acs.analchem.7b01681 ◽

2017 ◽

Vol 89 (15) ◽

pp. 8104-8111 ◽

Cited By ~ 15

Author(s):

Teng Luo ◽

Yuan Lu ◽

Shaoxiong Liu ◽

Danying Lin ◽

Junle Qu

Keyword(s):

Differential Diagnosis ◽

Basal Cell Carcinoma ◽

Cell Carcinoma ◽

Basal Cell ◽

Actinic Keratosis ◽

Screening Tool ◽

Bowen’S Disease ◽

Bowen's Disease

Download Full-text

Dermoscopy Clues in Pigmented Bowen's Disease

Dermatology Research and Practice ◽

10.1155/2010/464821 ◽

2010 ◽

Vol 2010 ◽

pp. 1-9 ◽

Cited By ~ 17

Author(s):

Daniela Gutiérrez-Mendoza ◽

Roberto Narro-Llorente ◽

Marcia Karam-Orantes ◽

Verónica Fonte-Avalos ◽

Eduwiges Martínez-Luna ◽

...

Keyword(s):

Differential Diagnosis ◽

Basal Cell Carcinoma ◽

Diagnostic Accuracy ◽

Cell Carcinoma ◽

Clinical Features ◽

Melanocytic Lesion ◽

Bowen’S Disease ◽

Bowen's Disease ◽

Pigmented Lesions ◽

Melanocytic Lesions

Pigmented tumors have similar clinical features that overlap and hamper diagnosis. Dermoscopy increases the diagnostic accuracy of doubtful melanocytic lesions and has been used as a noninvasive tool in the detection of pigmented lesions (PLs) like melanoma, basal cell carcinoma, and pigmented Bowen's disease (pBD). Our objective was to show the dermoscopic features of 2 cases of pBD and compare with the findings reported in the literature. Two dermoscopic images of biopsy proven pBD were retrospectively analyzed for dermoscopic patterns. Both cases showed brown regular globules, structureless brown and blue pigmentation, glomerular vessels, hypopigmented regression-like areas, and keratosis. These findings were similar to the cases reported previously. The dermoscopic diagnosis of pBD is based on the absence of criteria for a melanocytic lesion in the presence of glomerular vessels, regular brown globules and keratosis. Although pBD is rare, it should be included in the differential diagnosis of PLs, especially melanoma.

Download Full-text