scholarly journals Novel renal biomarkers of acute kidney injury and their implications

2021 ◽  
Vol 51 (3) ◽  
pp. 316-318
Author(s):  
Rinaldo Bellomo ◽  
Emily J. See

2020 ◽  
Vol 25 (44) ◽  
pp. 4695-4701 ◽  
Author(s):  
Georgios Karaolanis ◽  
Zachary F. Williams ◽  
Chris Bakoyiannis ◽  
Dimitrios Hadjis ◽  
Mitchell W. Cox ◽  
...  

: The widespread adoption of endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAA) is due to the obvious advantages of the procedure compared to the traditional open repair. However, these advantages have to be weighed against the increased risk of renal dysfunction with EVAR. The evaluation of the perioperative renal function after EVAR has been hampered by the lack of sensitive and specific biochemical markers of acute kidney injury (AKI). The purpose of this study was to summarize all novel renal biomarkers and to evaluate their clinical utility for the assessment of the kidney function after EVAR. A systematic review of the current literature, as the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement guidelines, was performed to identify relevant studies with novel renal biomarkers and EVAR. Pubmed and Scopus databases were systemically searched. Studies reporting on thoracic endovascular aortic repair (TEVAR), case reports, case series, letters to the editor, and systematic reviews were excluded. Neutrophil-Gelatinase-Associated Lipocalin, Cystatin C, Liver-type fatty-acid-binding protein were the most common among the eligible studies while Interleukin-18, Retinol binding protein, N-acetyle-b-D-glucosaminidase and microalbumin have a sparse appearance in the literature. These biomarkers have been assessed in plasma as well as urine samples with each sample material having its own advantages and drawbacks. Which of these biomarkers has the most potential for assessing postoperative renal failure after EVAR, remains to be proved. The few studies presented in the literature show the potential clinical utility of these biomarkers, but larger studies with longer follow-up are required to determine the precise relationship between these biomarkers and postoperative acute kidney injury.



2013 ◽  
Vol 22 (2) ◽  
pp. 234-241 ◽  
Author(s):  
Ravi Ghatanatti ◽  
Anita Teli ◽  
Sundeep Sanjivan Tirkey ◽  
Subhankar Bhattacharya ◽  
Gautam Sengupta ◽  
...  


2017 ◽  
Vol 43 (6) ◽  
pp. 883-886 ◽  
Author(s):  
Jill Vanmassenhove ◽  
Jan T. Kielstein ◽  
Marlies Ostermann




2017 ◽  
Vol 39 ◽  
pp. 1-8 ◽  
Author(s):  
Michele Andreucci ◽  
Teresa Faga ◽  
Antonio Pisani ◽  
Maria Perticone ◽  
Ashour Michael


Renal Failure ◽  
2012 ◽  
Vol 34 (9) ◽  
pp. 1100-1108 ◽  
Author(s):  
Stelios Kokkoris ◽  
Maria Parisi ◽  
Sofia Ioannidou ◽  
Evangelia Douka ◽  
Chrysoula Pipili ◽  
...  




2019 ◽  
Vol 13 (7) ◽  
pp. e0007486 ◽  
Author(s):  
Indira Ratnayake ◽  
Fahim Mohamed ◽  
Nicholas A. Buckley ◽  
Indika B. Gawarammana ◽  
Dhammika M. Dissanayake ◽  
...  


Critical Care ◽  
2011 ◽  
Vol 15 (S3) ◽  
Author(s):  
N Glassford ◽  
A Schneider ◽  
G Eastwood ◽  
L Peck ◽  
H Young ◽  
...  


2020 ◽  
Vol 6 (6) ◽  
pp. 1240-1247 ◽  
Author(s):  
Brian R. Lane ◽  
Stephen K. Babitz ◽  
Katerina Vlasakova ◽  
Allen Wong ◽  
Sabrina L. Noyes ◽  
...  


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