STIMULATION OF GROWTH HORMONE RELEASE BY LUTEINIZING HORMONE-RELEASING HORMONE AND MELANOCYTE-STIMULATING HORMONE-RELEASE INHIBITING HORMONE IN THE HYPOPHYSECTOMIZED RAT BEARING AN ECTOPIC PITUITARY

1976 ◽  
Vol 5 (6) ◽  
pp. 717-722 ◽  
Author(s):  
A. E. PANERAI ◽  
D. COCCHI ◽  
I. GIL-AD ◽  
V. LOCATELLI ◽  
G. L. ROSSI ◽  
...  
1977 ◽  
Vol 75 (1) ◽  
pp. 175-176 ◽  
Author(s):  
R. GOLDSTEIN ◽  
S. PAVEL

Institute of Endocrinology, Bucharest, Rumania (Received 29 March 1977) The mammalian pineal gland contains (Pavel, 1965) and synthesizes (Pavel, Goldstein, Ghinea & Calb, 1977) the nonapeptide arginine-vasotocin (AVT). Since luteinizing hormone releasing hormone (LH–RH), thyrotrophin releasing hormone (TRH) and growth hormone release-inhibiting hormone (somatostatin, SRIF) have now been localized not only in the brain, but also in the pineal gland (White, Hedlund, Weber, Rippel, Johnston & Wilber, 1974; Pelletier, Le Clerc, Dube, Labrie, Puviani, Arimura & Schally, 1975), we investigated the effects of these peptides on the release of AVT into the cerebrospinal fluid (CSF) of cats. Intracarotid injections of 0·1 μg LH-RH, TRH (Hoechst, Frankfurt), SRIF (Serono, Rome) or oxytocin (Syntocinon, Sandoz Ltd, Basel) in 0·5 ml saline were given to urethane-anaesthetized male cats weighing 3–4 kg. Controls received an equal volume of saline only. The pineal glands were removed 60 min after the injections, quickly homogenized, and extracted


1981 ◽  
Vol 10 (1) ◽  
pp. 51-57 ◽  
Author(s):  
Mark S. Gold ◽  
A. L. C. Pottash ◽  
David M. Martin ◽  
Lawrence B. Finn ◽  
Robert K. Davies

Ten female patients who satisfied objective criteria for the diagnosis of anorexia nervosa were given 500 ug of thyrotropin releasing hormone. Thyroid stimulating hormone and growth hormone responses were measured in duplicate by radioimmunoassay. These patients had a low normal Δ thyroid stimulating hormone but a delayed peak response. In addition, these patients had pathological growth hormone release in response to thyrotropin releasing hormone infusion. Both delayed peak thyroid stimulating hormone and growth hormone response to thyrotropin releasing hormone have been reported for patients with hypothalamic disorders.


Endocrinology ◽  
1976 ◽  
Vol 98 (3) ◽  
pp. 807-814 ◽  
Author(s):  
KENNETH A. UDESCHINI ◽  
DANIELA COCCHI ◽  
ALBERTO E. PANERA ◽  
IRIT GIL-AD ◽  
GIOVANNI L. ROSS ◽  
...  

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