An unusual case of clear cell sarcoma arising in the jejunum highlights the diagnostic value of molecular genetic techniques in establishing a correct diagnosis

2005 ◽  
Vol 46 (4) ◽  
pp. 472-474 ◽  
Author(s):  
R Achten ◽  
M Debiec-Rychter ◽  
I De Wever ◽  
R Sciot
2019 ◽  
Vol 144 (1) ◽  
pp. 119-123 ◽  
Author(s):  
Alessandro Pietro Aldera ◽  
Komala Pillay

Clear cell sarcoma of the kidney is an uncommon malignant pediatric renal neoplasm that typically presents in the 2- to 3-year age group and has a propensity for aggressive behavior and late relapses. Histologically, this tumor exhibits a great diversity of morphologic patterns that can mimic most other pediatric renal neoplasms, often leading to confusion and misdiagnosis. Until recently, adjunct immunohistochemical and molecular genetic tests to support the diagnosis were lacking. The presence of internal tandem duplications in BCL-6 coreceptor (BCOR) and a translocation t(10;17) creating the fusion gene YWHAE-NUTM2B/E have now been well accepted. Immunohistochemistry for BCOR has also been shown to be a sensitive and specific marker for clear cell sarcoma of the kidney in the context of pediatric renal tumors. Improved intensive chemotherapy regimens have influenced the clinical course of the disease, with late relapses now being less frequent and the brain having overtaken bone as the most common site of relapse.


1998 ◽  
Vol 88 (9) ◽  
pp. 457-461 ◽  
Author(s):  
MK Brekke ◽  
K Northcote ◽  
WE Temple

Clear cell sarcoma is an uncommon malignant neoplasm that, on rare occasion, invades osseous structures. The authors present a case of clear cell sarcoma that appears to have an osseous origin and that was discovered on a routine radiograph of the foot.


2018 ◽  
Vol 61 (2) ◽  
pp. 245
Author(s):  
Ranjan Agrawal ◽  
Prabal Deb ◽  
Jagdamba Sharan ◽  
Parbodh Kumar

2013 ◽  
Vol 2 (3) ◽  
pp. 152
Author(s):  
Shantveer Uppin ◽  
Jay Mehta ◽  
Kalpathi Krishnamani ◽  
LingaVijay Gandhi ◽  
Monalisa Hui

2012 ◽  
Vol 2 (4) ◽  
pp. 284-285
Author(s):  
Juhi Singhala ◽  
◽  
Avanish Saxena ◽  
Pallav Agrawal ◽  
Manish Budhiraja ◽  
...  

2002 ◽  
Vol 99 (4) ◽  
pp. 560-567 ◽  
Author(s):  
Ioannis Panagopoulos ◽  
Fredrik Mertens ◽  
Maria Dêbiec-Rychter ◽  
Margareth Isaksson ◽  
Janusz Limon ◽  
...  

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