Efficacy of a 0.0584% hydrocortisone aceponate spray in the management of canine atopic dermatitis: a randomised, double blind, placebo-controlled trial

2009 ◽  
Vol 20 (3) ◽  
pp. 191-198 ◽  
Author(s):  
Tim Nuttall ◽  
Ralf Mueller ◽  
Emmanuel Bensignor ◽  
Maite Verde ◽  
Chiara Noli ◽  
...  
2014 ◽  
Vol 70 (6) ◽  
pp. 1076-1082 ◽  
Author(s):  
Sherief R. Janmohamed ◽  
Arnold P. Oranje ◽  
Arjan C. Devillers ◽  
Dimitris Rizopoulos ◽  
Marinus C.G. van Praag ◽  
...  

2014 ◽  
Vol 17 (2) ◽  
pp. 371-373 ◽  
Author(s):  
M. Fujimura ◽  
H. Ishimaru ◽  
Y. Nakatsuji

Abstract This study investigated effects of a fluoxetine (selective serotonin reuptake inhibitors; SSRI, 1 mg/kg) on pruritus in canine atopic dermatitis (CAD). After 4-weeks of base-line observation, 8 dogs with CAD entered a 2-months randomized, double-blind, placebo-controlled, crossover trial comparing fluoxetine with placebo. Clinical efficacy was evaluated using a Canine Atopic Dermatitis Extent and Severity Index (CADESI-03) and Pruritus Visual Analog Scale (PVAS). Six dogs completed the study [two out of eight dogs (both of them were Shiba Inu) dropped out from the study due to a depression]. CADESI-03 and PVAS between fluoxetine and placebo showed no significant difference statistically (P>0.05 and P>0.05 respectively). Fluoxetine showed no efficacy on pruritus in CAD. Further researches are needed for the treatment on pruritus of CAD


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