From Ag phenotyping to molecular genetics: apolipoprotein B, serum lipid levels and coronary artery disease in Finland

2008 ◽  
Vol 46 (1) ◽  
pp. 71-76 ◽  
Author(s):  
Matti J. Tikkanen ◽  
Tiina Heliö
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Molecular Genetics ◽  
Apolipoprotein B ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Artery Disease

Non-fasting samples for estimation of serum lipid levels in patients with coronary artery disease

2014 ◽  
Vol 3 (3) ◽  
pp. 206
Author(s):  
P Srilakshmi ◽  
MF Gopinath ◽  
MVijaya Bhaskar ◽  
K Rambabu ◽  
GSrinivasa Reddy
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Lipid ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Artery Disease

scholarly journals USF1 Contributes to High Serum Lipid Levels in Dutch FCHL Families and U.S. Whites With Coronary Artery Disease

2007 ◽  
Vol 27 (10) ◽  
pp. 2222-2227 ◽  
Author(s):  
Jenny C. Lee ◽  
Daphna Weissglas-Volkov ◽  
Mira Kyttälä ◽  
Janet S. Sinsheimer ◽  
Anne Jokiaho ◽  
...  
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Lipid ◽  
High Serum ◽  
Lipid Levels ◽  
Serum Lipid Levels ◽  
Artery Disease

scholarly journals Preliminary Analysis of PON3 rs2375003 Polymorphism in Pakistani Patients with Coronary Artery Disease

2019 ◽  
Vol 67 (3) ◽  
pp. 141-148
Author(s):  
Maryam Sameem ◽  
Muhammad Arshad
Keyword(s):  
Coronary Artery Disease ◽  
Coronary Artery ◽  
Serum Lipid ◽  
Density Lipoprotein ◽  
Lipoprotein Cholesterol ◽  
Lipid Levels ◽  
Pakistani Population ◽  
Serum Lipid Levels ◽  
Genotype Frequencies ◽  
Artery Disease

Coronary artery disease (CAD) is an inflammatory heart disease characterized by the narrowing of coronary arteries. Paraoxonase 3 (PON3) is a candidate gene for protection against CAD development as it reduces oxidative stress and lipid peroxidation. The present study aimed to explore the association of PON3 rs2375003 polymorphism with CAD development and serum lipid levels in the Pakistani population. Study subjects included 300 CAD patients and 300 age and sex matched healthy individuals. The genotyping of rs2375003 polymorphism was done using an allele specific polymerase chain reaction and serum lipid levels were determined. In this study, the genotype frequencies of rs2375003 polymorphismin in CAD patients were TT (2%), CT (8%), CC (90%) as compared to TT (3%), CT (6%), CC (91%) in the healthy subjects. No association was observed between rs2375003 polymorphism and CAD risk (p>0.05). The CT genotype of rs2375003 polymorphism marginally increased the risk for CAD development (OR: 1.36; 95% CI 0.72-2.56) by causing a marginal rise in total cholesterol, low density lipoprotein cholesterol and triglyceride levels, and a marginal drop in high density lipoprotein cholesterol levels. The CT genotype of rs2375003 polymorphism and altered lipid levels might act as potential risk factors in the etiology of CAD in the Pakistani population.

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