A SUPPLEMENTARY LIST OF AMINO-ACID DERIVATIVES WHICH ARE USEFUL IN PEPTIDE SYNTHESIS

Author(s):  
G. A. Fletcher ◽  
J. H. Jones
2001 ◽  
Vol 637-639 ◽  
pp. 349-355 ◽  
Author(s):  
Jan Sehnert ◽  
Alexandra Hess ◽  
Nils Metzler-Nolte

1977 ◽  
Vol 55 (5) ◽  
pp. 906-910 ◽  
Author(s):  
S. T. Cheung ◽  
N. Leo Benoiton

The preparation of enantiomerically pure N-tert-butyloxycarbonyl,N-methylamino acids by N-methylation of the parent amino acid derivatives using sodium hydride and methyl iodide in tetrahydrofuran at room temperature is described for neutral amino acids including O-benzyl-protected threonine and tyrosine. Methylation of the O-benzylserine derivative under these conditions gives the N-methyldehydroalanine derivative. The β-elimination is completely suppressed, giving the corresponding N-methylserine derivative when the reaction is carried out at 5 °C. Other related data on N-methylation and N-methylamino acid derivatives are presented.


ChemInform ◽  
2010 ◽  
Vol 26 (8) ◽  
pp. no-no
Author(s):  
L. LANKIEWICZ ◽  
B. NYASSE ◽  
B. FRANSSON ◽  
L. GREHN ◽  
U. RAGNARSSON

1994 ◽  
Vol 17 (13) ◽  
pp. 2759-2775 ◽  
Author(s):  
Gy. Szókán ◽  
Sz. Hadfi ◽  
K. Krizsán ◽  
A. Liembeck ◽  
I. Krecz ◽  
...  

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