Second supplementary list of amino-acid derivatives useful in peptide synthesis

2009 ◽  
Vol 25 (2) ◽  
pp. 213-223 ◽  
Author(s):  
DAVID W. THOMAS ◽  
JOHN H. JONES
Keyword(s):  
Amino Acid ◽  
Peptide Synthesis ◽  
Amino Acid Derivatives ◽  
Supplementary List

Solution phase peptide synthesis with ferrocenyl amino acid derivatives

2001 ◽  
Vol 637-639 ◽  
pp. 349-355 ◽  
Author(s):  
Jan Sehnert ◽  
Alexandra Hess ◽  
Nils Metzler-Nolte
Keyword(s):  
Amino Acid ◽  
Peptide Synthesis ◽  
Solution Phase ◽  
Amino Acid Derivatives

N-Methylamino acids in peptide synthesis. V. The synthesis of N-tert-butyloxycarbonyl, N-methylamino acids by N-methylation

1977 ◽  
Vol 55 (5) ◽  
pp. 906-910 ◽  
Author(s):  
S. T. Cheung ◽  
N. Leo Benoiton
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Methyl Iodide ◽  
Peptide Synthesis ◽  
Room Temperature ◽  
Sodium Hydride ◽  
Amino Acid Derivatives ◽  
Enantiomerically Pure ◽  
Neutral Amino Acids ◽  
Related Data

The preparation of enantiomerically pure N-tert-butyloxycarbonyl,N-methylamino acids by N-methylation of the parent amino acid derivatives using sodium hydride and methyl iodide in tetrahydrofuran at room temperature is described for neutral amino acids including O-benzyl-protected threonine and tyrosine. Methylation of the O-benzylserine derivative under these conditions gives the N-methyldehydroalanine derivative. The β-elimination is completely suppressed, giving the corresponding N-methylserine derivative when the reaction is carried out at 5 °C. Other related data on N-methylation and N-methylamino acid derivatives are presented.

ChemInform Abstract: Synthesis of Amino Acid Derivatives Substituted in the Backbone with Stable Isotopes for Application in Peptide Synthesis.

ChemInform ◽  
2010 ◽  
Vol 26 (8) ◽  
pp. no-no
Author(s):  
L. LANKIEWICZ ◽  
B. NYASSE ◽  
B. FRANSSON ◽  
L. GREHN ◽  
U. RAGNARSSON
Keyword(s):  
Stable Isotopes ◽  
Amino Acid ◽  
Peptide Synthesis ◽  
Amino Acid Derivatives

HPLC Determination of Enantiomeric Purity of Protected Amino Acid Derivatives Used in Peptide Synthesis

1994 ◽  
Vol 17 (13) ◽  
pp. 2759-2775 ◽  
Author(s):  
Gy. Szókán ◽  
Sz. Hadfi ◽  
K. Krizsán ◽  
A. Liembeck ◽  
I. Krecz ◽  
...  
Keyword(s):  
Amino Acid ◽  
Peptide Synthesis ◽  
Enantiomeric Purity ◽  
Hplc Determination ◽  
Amino Acid Derivatives ◽  
Protected Amino Acid
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