Correlation between early neonatal diet and atopic symptoms up to 5-7 years of age in very low birth weight infants: follow-up of randomized, double-blind study

2009 ◽  
Vol 20 (5) ◽  
pp. 458-466 ◽  
Author(s):  
Przemko Kwinta ◽  
Piotr Sawiec ◽  
Malgorzata Klimek ◽  
Grzegorz Lis ◽  
Ewa Cichocka-Jarosz ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Blind Study ◽  
Double Blind Study ◽  
Low Birth Weight Infants ◽  
Double Blind

Results of Controlled Double-Blind Study of Thyroid Replacement in Very Low-Birth-Weight Premature Infants with Hypothyroxinemia

PEDIATRICS ◽  
1984 ◽  
Vol 73 (3) ◽  
pp. 301-305 ◽  
Author(s):  
Parveen Chowdhry ◽  
John W. Scanlon ◽  
Richard Auerbach ◽  
Val Abbassi
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Thyrotropin Releasing Hormone ◽  
Blind Study ◽  
Double Blind Study ◽  
Double Blind ◽  
Releasing Hormone ◽  
Serum T4

The nature of hypothyroxinemia in sick very low-birth-weight (VLBW) infants was evaluated by assessment of the hypothalamic-pituitary axis and by the clinical response to thyroxine (T4) therapy. Twenty-three very low-birth-weight infants of gestational age 26 to 28 weeks, whose serum T4 concentrations were 4 µg/dL on two occasions, and thyrotropin < 20 µU/mL, were included in a double-blind study. Following a thyrotropin-releasing hormone stimulation test, babies were given either T4 or placebo. Nine babies were thyrotropin-releasing hormone tested prior to therapy; four babies, two from each group, were tested 1 to 2 weeks after therapy. In 11 untreated babies, mean base line serum thyrotropin of 7.0 ± 1.4 rose to 23.7 ± 4.1 µU/mL in 30 minutes. This response was not significantly greater than the observed response in full-term babies, 23.7 ± 4.1 v 16.6 ± 0.97 µU/mL, respectively, P > .05. In two babies treated with T4 the thyrotropin response to thyrotropin-releasing hormone was completely suppressed. Serial serum T4 determinations showed normalization in both groups after a similar time interval. There was no beneficial effect of T4 therapy on growth of head circumference, length, or weight. Developmental data revealed no significant differences in the mental, motor, or gross neurologic outcome in the treated and nontreated infants after 1 year of follow-up. These observations imply that hypothyroxinemia in sick preterm infants is not a direct consequence of hypothyroidism. Despite the lack of demonstrable short-term beneficial effects of T4 therapy, follow-up studies are necessary to resolve the question of long-term benefits.

Primary Follow-up Care in a Multidisciplinary Setting Enhances Catch-up Growth of Very-low-birth-weight Infants

1997 ◽  
Vol 97 (4) ◽  
pp. 386-390 ◽  
Author(s):  
STEPHANIE R. BRYSON ◽  
LEA THERIOT ◽  
NELL J. RYAN ◽  
JANET POPE ◽  
NANCY TOLMAN ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Follow Up Care ◽  
Catch Up

SYSTEMIC HYPERTENSION FOLLOWING OCULAR ADMINISTRATION OF 10% PHENYLEPHRINE IN THE NEONATE

PEDIATRICS ◽  
1973 ◽  
Vol 51 (6) ◽  
pp. 1032-1036 ◽  
Author(s):  
Virginia Borromeo-McGrail ◽  
Joseph Bordiuk ◽  
Hans Keitel
Keyword(s):  
Blood Pressure ◽  
Birth Weight ◽  
Low Birth Weight ◽  
Systemic Blood Pressure ◽  
Systemic Effect ◽  
Systemic Hypertension ◽  
Double Blind Study ◽  
Eye Drops ◽  
Low Birth Weight Infants ◽  
Double Blind

The effect of ophthalmic instillation of 10% phenylephrine on systemic blood pressure in the neonate has not been previously evaluated, despite reports of adverse reactions. The effect of 10% and 2½% phenylephrine eye drops in healthy low birth weight neonates was compared in a double-blind study. Blood pressure showed a rise of 12 to 16 mm Hg in systole and 10 to 14 mm Hg in diastole following administration of 10% phenylephrine. Blood pressure remained stable in infants receiving 2½% phenylephrine. Consistent, although more variable, increases in blood pressure were noted in eight low birth weight infants given 10% phenylephrine eye drops in a nonblind study. Complete mydriasis was achieved with 2½% phenylephrine as well as with 10%. Neither concentration had an effect on pulse or respiratory rates. Cutaneous administration of either 10% or 2½% phenylephrine to abdominal skin produced local blanching but no systemic effect. To avoid potentially dangerous sequelae from iatrogenic hypertension, it is recommended that not more than one drop of 2½% phenylephrine in each eye be administered to neonates for mydriasis.

Follow-up of NICU Graduates: Why, What, and by Whom

1995 ◽  
Vol 10 (5) ◽  
pp. 213-225 ◽  
Author(s):  
Marie C. Mccormick ◽  
Jane E. Stewart ◽  
Robyn Cohen ◽  
Marsha Joselaw ◽  
Priscilla S. Osborne ◽  
...  
Keyword(s):  
Intensive Care ◽  
Birth Weight ◽  
Data Collection ◽  
Low Birth Weight ◽  
Neonatal Intensive Care ◽  
Very Low Birth Weight ◽  
Low Birth Weight Infants ◽  
Collection Strategies

Follow-up of the graduates of neonatal intensive care is an important component of the provision of such care. However, the objectives of these programs and their data-collection strategies vary widely. This report describes the potential objectives and different data-collection strategies. It then reviews briefly what is known about the outcomes of very low birth weight infants to guide the development of assessment packets: Finally, we describe the operation of our program and activities of our team to illustrate the follow-up experience in a large multi-institution program.

Two-Year Follow-up of a Randomized Controlled Nutrition Intervention Trial in Very Low-Birth-Weight Infants

2016 ◽  
pp. 014860711667819 ◽  
Author(s):  
Jorine A. Roelants ◽  
Hester Vlaardingerbroek ◽  
Chris H. P. van den Akker ◽  
Rogier C. J. de Jonge ◽  
Johannes B. van Goudoever ◽  
...  
Keyword(s):  
Birth Weight ◽  
Low Birth Weight ◽  
Very Low Birth Weight ◽  
Nutrition Intervention ◽  
Intervention Trial ◽  
Low Birth Weight Infants ◽  
Randomized Controlled
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